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Data-driven medicinal chemistry in the era of big data

Drug discovery today, 2014-07, Vol.19 (7), p.859-868

2014

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The presence of five cyclic nucleotide phosphodiesterase isoenzyme activities in bovine tracheal smooth muscle and the functional effects of selective inhibitors

British journal of pharmacology, 1991-10, Vol.104 (2), p.471-477

1991

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Human bronchial cyclic nucleotide phosphodiesterase isoenzymes: biochemical and pharmacological analysis using selective inhibitors

British journal of pharmacology, 1992-08, Vol.106 (4), p.1028-1034

1992

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Modulation of spasmogen‐stimulated Ins(1,4,5)P3 generation and functional responses by selective inhibitors of types 3 and 4 phosphodiesterase in airways smooth muscle

British journal of pharmacology, 1998-05, Vol.124 (1), p.47-54

1998

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Modulation of spasmogen‐stimulated Ins(1,4,5)P 3 generation and functional responses by selective inhibitors of types 3 and 4 phosphodiesterase in airways smooth muscle

British journal of pharmacology, 2009-02, Vol.124 (1), p.47-54

2009

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Differential modulation of tissue function and therapeutic potential of selective inhibitors of cyclic nucleotide phosphodiesterase isoenzymes

Trends in Pharmacological Sciences, 1991, Vol.12 (1), p.19-27

1991

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Human bronchial cyclic nucleotide phosphodiesterase isoenzymes: biochemical and pharmacological analysis using selective inhibitors

British journal of pharmacology, 1992-08, Vol.106 (4), p.1028-1034

1992

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Old antithrombotics: ready to retire?

Expert opinion on investigational drugs, 2001-05, Vol.10 (5), p.785-787

2001

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The analysis and assay of cyclic nucleotide phosphodiesterase isoenzyme activity

Methods in molecular biology (Clifton, N.J.), 1995, Vol.41, p.129

1995

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Mitiple forms of calmodulin-activated cyclic nucleotide phosphodiesterase (PDE) in rabbit veniricular myocardium

Journal of molecular and cellular cardiology, 1990-05, Vol.22, p.S6-S6

1990

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Effects of selective phosphodiesterase inhibition on cyclic AMP hydrolysis in rat cerebral cortical slices

British journal of pharmacology, 1990-01, Vol.99 (1), p.47-52

1990

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The fiftieth anniversary of the British Journal of Nutrition

British journal of nutrition, 1997-01, Vol.77 (1), p.1-2

1997

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Nootropics and metabolically active compounds in Alzheimer's disease

Biochemical Society transactions, 1989-02, Vol.17 (1), p.83-85

Nicholson, C D

1989

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The σ ligand 1,3-di-o-tolylguanidine depresses amino acid-induced excitation non-selectively in rat brain

European journal of pharmacology, 1992-04, Vol.214 (2), p.169-173

1992

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The lack of utility of the rat vas deferens as a functional bioassay for σ ligands

European journal of pharmacology, 1991-02, Vol.193 (2), p.139-143

1991

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Positive inotropism and cAMP elevation by cyclic nucleotide phosphodiesterase inhibitors in rat heart

Journal of molecular and cellular cardiology, 1990-05, Vol.22, p.S104-S104

1990

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Org 30029 stimulates cardiac myofilament force and ATPase activity

Journal of molecular and cellular cardiology, 1991-07, Vol.23, p.S85-S85

1991

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Rock-Tenn Co. announces the acquisition of Rite Paper Products Inc

Business Wire, 1997, p.1

Nicholson, David C

1997

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Rock-Tenn Company names Shuster president

Business Wire, 1995, p.1

Nicholson, David C

1995

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Rock-Tenn Company reports record year-end and fourth quarter results

Business Wire, 1994, p.1

Nicholson, David C

1994

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DISSOCIATION CONSTANTS OF ISOPRENALINE AND ORCIPRENALINE AND THEIR RELATIVE EFFICACIES ON GUINEA‐PIG ISOLATED ATRIA DETERMINED BY USE OF AN IRREVERSIBLE β‐ADRENOCEPTOR ANTAGONIST

British journal of pharmacology, 1981-04, Vol.72 (4), p.635-643

1981

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Irreversible β-adrenoceptor blockade of atrial rate and tension responses

European journal of pharmacology, 1978-12, Vol.52 (3), p.259-269

1978

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New trends in biochar pyrolysis and modification strategies: feedstock, pyrolysis conditions, sustainability concerns and implications for soil amendment

Soil use and management, 2020-07, Vol.36 (3), p.358-386

2020

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Molecular simulation of flow-enhanced nucleation in n-eicosane melts under steady shear and uniaxial extension

The Journal of chemical physics, 2016-12, Vol.145 (24), p.244903-244903

2016

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Idiopathic Pulmonary Fibrosis (an Update) and Progressive Pulmonary Fibrosis in Adults: An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline

American journal of respiratory and critical care medicine, 2022-05, Vol.205 (9), p.e18-e47

2022

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Data-driven medicinal chemistry in the era of big data

The presence of five cyclic nucleotide phosphodiesterase isoenzyme activities in bovine tracheal smooth muscle and the functional effects of selective inhibitors

Human bronchial cyclic nucleotide phosphodiesterase isoenzymes: biochemical and pharmacological analysis using selective inhibitors

Modulation of spasmogen‐stimulated Ins(1,4,5)P3 generation and functional responses by selective inhibitors of types 3 and 4 phosphodiesterase in airways smooth muscle

Modulation of spasmogen‐stimulated Ins(1,4,5)P 3 generation and functional responses by selective inhibitors of types 3 and 4 phosphodiesterase in airways smooth muscle

Differential modulation of tissue function and therapeutic potential of selective inhibitors of cyclic nucleotide phosphodiesterase isoenzymes

Human bronchial cyclic nucleotide phosphodiesterase isoenzymes: biochemical and pharmacological analysis using selective inhibitors

Old antithrombotics: ready to retire?

The analysis and assay of cyclic nucleotide phosphodiesterase isoenzyme activity

Mitiple forms of calmodulin-activated cyclic nucleotide phosphodiesterase (PDE) in rabbit veniricular myocardium

Effects of selective phosphodiesterase inhibition on cyclic AMP hydrolysis in rat cerebral cortical slices

The fiftieth anniversary of the British Journal of Nutrition

Nootropics and metabolically active compounds in Alzheimer's disease

The σ ligand 1,3-di-o-tolylguanidine depresses amino acid-induced excitation non-selectively in rat brain

The lack of utility of the rat vas deferens as a functional bioassay for σ ligands

Positive inotropism and cAMP elevation by cyclic nucleotide phosphodiesterase inhibitors in rat heart

Org 30029 stimulates cardiac myofilament force and ATPase activity

Rock-Tenn Co. announces the acquisition of Rite Paper Products Inc

Rock-Tenn Company names Shuster president

Rock-Tenn Company reports record year-end and fourth quarter results

DISSOCIATION CONSTANTS OF ISOPRENALINE AND ORCIPRENALINE AND THEIR RELATIVE EFFICACIES ON GUINEA‐PIG ISOLATED ATRIA DETERMINED BY USE OF AN IRREVERSIBLE β‐ADRENOCEPTOR ANTAGONIST

Irreversible β-adrenoceptor blockade of atrial rate and tension responses

New trends in biochar pyrolysis and modification strategies: feedstock, pyrolysis conditions, sustainability concerns and implications for soil amendment

Molecular simulation of flow-enhanced nucleation in n-eicosane melts under steady shear and uniaxial extension

Idiopathic Pulmonary Fibrosis (an Update) and Progressive Pulmonary Fibrosis in Adults: An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline

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