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Emergence of multidrug-resistant, extensively drug-resistant and untreatable gonorrhea

Future microbiology, 2012-12, Vol.7 (12), p.1401-1422

2012

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Commensal Neisseria species share immune suppressive mechanisms with Neisseria gonorrhoeae

PloS one, 2023-04, Vol.18 (4), p.e0284062-e0284062

2023

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Developing evidence-based resources for evaluating postgraduate trainees in the biomedical sciences

PloS one, 2022-12, Vol.17 (12), p.e0278297-e0278297

2022

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Molecular and Structural Analysis of Mosaic Variants of Penicillin-Binding Protein 2 Conferring Decreased Susceptibility to Expanded-Spectrum Cephalosporins in Neisseria gonorrhoeae: Role of Epistatic Mutations

Biochemistry (Easton), 2010-09, Vol.49 (37), p.8062-8070

2010

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Identification of Amino Acids Conferring High-Level Resistance to Expanded-Spectrum Cephalosporins in the penA Gene from Neisseria gonorrhoeae Strain H041

Antimicrobial Agents and Chemotherapy, 2013-07, Vol.57 (7), p.3029-3036

2013

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Genetics of Chromosomally Mediated Intermediate Resistance to Ceftriaxone and Cefixime in Neisseria gonorrhoeae

Antimicrobial Agents and Chemotherapy, 2009-09, Vol.53 (9), p.3744-3751

2009

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Commentary on ‘Identification and characterization of select oxysterols as ligands for GPR17’

British journal of pharmacology, 2023-04, Vol.180 (8), p.1186-1187

Nicholas, Robert A.

2023

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Is GPR17 a P2Y/leukotriene receptor? examination of uracil nucleotides, nucleotide sugars, and cysteinyl leukotrienes as agonists of GPR17

The Journal of pharmacology and experimental therapeutics, 2013-10, Vol.347 (1), p.38

2013

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Physiological Regulation of ATP Release at the Apical Surface of Human Airway Epithelia

The Journal of biological chemistry, 2006-08, Vol.281 (32), p.22992-23002

2006

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Porin-Mediated Antibiotic Resistance in Neisseria gonorrhoeae: Ion, Solute, and Antibiotic Permeation through PIB Proteins with penB Mutations

Journal of Bacteriology, 2006-04, Vol.188 (7), p.2300-2308

2006

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PubMLST for Antigen Allele Mining to Inform Development of Gonorrhea Protein-Based Vaccines

Frontiers in microbiology, 2018-12, Vol.9, p.2971-2971

2018

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Crystal Structures of Penicillin-binding Protein 2 from Penicillin-susceptible and -resistant Strains of Neisseria gonorrhoeae Reveal an Unexpectedly Subtle Mechanism for Antibiotic Resistance

The Journal of biological chemistry, 2009-01, Vol.284 (2), p.1202-1212

2009

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Structural Modifications of UMP, UDP, and UTP Leading to Subtype-Selective Agonists for P2Y2, P2Y4, and P2Y6 Receptors

Journal of medicinal chemistry, 2011-04, Vol.54 (8), p.2878-2890

2011

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High-Level Chromosomally Mediated Tetracycline Resistance in Neisseria gonorrhoeae Results from a Point Mutation in the rpsJ Gene Encoding Ribosomal Protein S10 in Combination with the mtrR and penB Resistance Determinants

Antimicrobial Agents and Chemotherapy, 2005-10, Vol.49 (10), p.4327-4334

2005

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High-throughput screening for novel inhibitors of Neisseria gonorrhoeae penicillin-binding protein 2

PloS one, 2012-09, Vol.7 (9), p.e44918

2012

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Key Determinants of Nucleotide-Activated G Protein-Coupled P2Y2 Receptor Function Revealed by Chemical and Pharmacological Experiments, Mutagenesis and Homology Modeling

Journal of medicinal chemistry, 2009-05, Vol.52 (9), p.2762-2775

2009

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Identification and Analysis of Amino Acid Mutations in Porin IB That Mediate Intermediate-Level Resistance to Penicillin and Tetracycline in Neisseria gonorrhoeae

Antimicrobial Agents and Chemotherapy, 2002-09, Vol.46 (9), p.2811-2820

2002

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Recognition of the β-lactam carboxylate triggers acylation of Neisseria gonorrhoeae penicillin-binding protein 2

The Journal of biological chemistry, 2019-09, Vol.294 (38), p.14020-14032

2019

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Endoplasmic Reticulum/Golgi Nucleotide Sugar Transporters Contribute to the Cellular Release of UDP-sugar Signaling Molecules

The Journal of biological chemistry, 2009-05, Vol.284 (18), p.12572-12583

2009

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Mutations in ponA, the Gene Encoding Penicillin-Binding Protein 1, and a Novel Locus, penC, Are Required for High-Level Chromosomally Mediated Penicillin Resistance in Neisseria gonorrhoeae

Antimicrobial Agents and Chemotherapy, 2002-03, Vol.46 (3), p.769-777

2002

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Voltage-dependent anion channel-1 (VDAC-1) contributes to ATP release and cell volume regulation in murine cells

The Journal of general physiology, 2004-11, Vol.124 (5), p.513-526

2004

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Overexpression of the MtrC-MtrD-MtrE Efflux Pump Due to an mtrR Mutation Is Required for Chromosomally Mediated Penicillin Resistance in Neisseria gonorrhoeae

Journal of Bacteriology, 2002-10, Vol.184 (20), p.5619-5624

2002

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Mutations in penicillin-binding protein 2 from cephalosporin-resistant Neisseria gonorrhoeae hinder ceftriaxone acylation by restricting protein dynamics

The Journal of biological chemistry, 2020-05, Vol.295 (21), p.7529-7543

2020

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Crystal Structure of Escherichia coli Penicillin-Binding Protein 5 Bound to a Tripeptide Boronic Acid Inhibitor: A Role for Ser-110 in Deacylation

Biochemistry (Easton), 2005-06, Vol.44 (23), p.8207-8217

2005

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Insights into platelet P2Y12 receptor activation

Blood, 2015-02, Vol.125 (6), p.893-895

Nicholas, Robert A.

2015

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