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Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737

Cancer research (Chicago, Ill.), 2007-02, Vol.67 (3), p.1176-1183

2007

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X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

Nature (London), 1996-05, Vol.381 (6580), p.335-341

1996

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Human Chk1 Expression Is Dispensable for Somatic Cell Death and Critical for Sustaining G2 DNA Damage Checkpoint

Molecular cancer therapeutics, 2003-06, Vol.2 (6), p.543-548

2003

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Bexarotene (LGD1069, Targretin), a selective retinoid X receptor agonist, prevents and reverses gemcitabine resistance in NSCLC cells by modulating gene amplification

Cancer research (Chicago, Ill.), 2007-05, Vol.67 (9), p.4425-4433

2007

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Survivin Enhances Aurora-B Kinase Activity and Localizes Aurora-B in Human Cells

The Journal of biological chemistry, 2003-01, Vol.278 (1), p.486-490

2003

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Highly sensitive proximity mediated immunoassay reveals HER2 status conversion in the circulating tumor cells of metastatic breast cancer patients

Proteome science, 2011-12, Vol.9 (1), p.75-75, Article 75

2011

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Identification of Chaulmoogric Acid as a Small Molecule Activator of Protein Phosphatase 5

Applied biochemistry and biotechnology, 2010-03, Vol.160 (5), p.1450-1459

2010

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Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL

Journal of medicinal chemistry, 2007-02, Vol.50 (4), p.641-662

2007

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Down-regulation of Survivin by Antisense Oligonucleotides Increases Apoptosis, Inhibits Cytokinesis and Anchorage-Independent Growth

Neoplasia (New York, N.Y.), 2000-05, Vol.2 (3), p.235-241

2000

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NMR structure and mutagenesis of the FADD (Mort1) death-effector domain

Nature (London), 1998-04, Vol.392 (6679), p.941-945

1998

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Development of a high-throughput fluorescence polarization assay for Bcl-xL

Analytical biochemistry, 2002-08, Vol.307 (1), p.70-75

2002

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Potentiating the naturally occurring process for repair of damaged heart

Current pharmaceutical design, 2014-04, Vol.20 (12), p.1950

2014

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Discovery of novel inhibitors of Bcl-xL using multiple high-throughput screening platforms

Analytical biochemistry, 2004-05, Vol.328 (2), p.131-138

2004

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Synthesis and Biological Evaluation of 2-Indolyloxazolines as a New Class of Tubulin Polymerization Inhibitors. Discovery of A-289099 as an Orally Active Antitumor Agent

Bioorganic & medicinal chemistry letters, 2002-02, Vol.12 (3), p.465-469

2002

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Distinctive Roles of PHAP Proteins and Prothymosin-α in a Death Regulatory Pathway

Science (American Association for the Advancement of Science), 2003-01, Vol.299 (5604), p.223-226

2003

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Novel One-Pot Total Syntheses of Deoxyvasicinone, Mackinazolinone, Isaindigotone, and Their Derivatives Promoted by Microwave Irradiation

Organic letters, 2005-07, Vol.7 (15), p.3363-3366

2005

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Enhanced Secretory Production of a Single-Chain Antibody Fragment from Bacillus subtilis by Coproduction of Molecular Chaperones

Journal of Bacteriology, 1998-06, Vol.180 (11), p.2830-2835

1998

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Rapid Colchicine Competition-Binding Scintillation Proximity Assay Using Biotin-Labeled Tubulin

BioTechniques, 2000-07, Vol.29 (1), p.156-160

2000

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Biological Activity of A-289099: An Orally Active Tubulin-binding Indolyloxazoline Derivative

Molecular cancer therapeutics, 2003-03, Vol.2 (3), p.227-233

2003

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Crystal structure of HsEg5 in complex with clinical candidate CK0238273 provides insight into inhibitory mechanism, potency, and specificity

Biochemical and biophysical research communications, 2008-08, Vol.372 (4), p.565-570

2008

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NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP

Nature (London), 1999-10, Vol.401 (6755), p.818-822

1999

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Identification of Polymorphisms Associated with Hypertriglyceridemia and Prolonged Survival Induced by Bexarotene in Treating Non-small Cell Lung Cancer

Anticancer research, 2011-06, Vol.31 (6), p.2303-2311

2011

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Aryl tetrahydropyridine inhibitors of farnesyltransferase: glycine, phenylalanine and histidine derivatives

Bioorganic & medicinal chemistry letters, 2003-04, Vol.13 (7), p.1359-1362

2003

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Crystal Structure and Mutagenic Analysis of the Inhibitor-of-Apoptosis Protein Survivin

Molecular cell, 2000, Vol.6 (1), p.173-182

2000

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Blocking CHK1 Expression Induces Apoptosis and Abrogates the G2 Checkpoint Mechanism

Neoplasia (New York, N.Y.), 2001, Vol.3 (5), p.411-419

2001

Volltextzugriff (PDF)

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Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

Human Chk1 Expression Is Dispensable for Somatic Cell Death and Critical for Sustaining G2 DNA Damage Checkpoint

Bexarotene (LGD1069, Targretin), a selective retinoid X receptor agonist, prevents and reverses gemcitabine resistance in NSCLC cells by modulating gene amplification

Survivin Enhances Aurora-B Kinase Activity and Localizes Aurora-B in Human Cells

Highly sensitive proximity mediated immunoassay reveals HER2 status conversion in the circulating tumor cells of metastatic breast cancer patients

Identification of Chaulmoogric Acid as a Small Molecule Activator of Protein Phosphatase 5

Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL

Down-regulation of Survivin by Antisense Oligonucleotides Increases Apoptosis, Inhibits Cytokinesis and Anchorage-Independent Growth

NMR structure and mutagenesis of the FADD (Mort1) death-effector domain

Development of a high-throughput fluorescence polarization assay for Bcl-xL

Potentiating the naturally occurring process for repair of damaged heart

Discovery of novel inhibitors of Bcl-xL using multiple high-throughput screening platforms

Synthesis and Biological Evaluation of 2-Indolyloxazolines as a New Class of Tubulin Polymerization Inhibitors. Discovery of A-289099 as an Orally Active Antitumor Agent

Distinctive Roles of PHAP Proteins and Prothymosin-α in a Death Regulatory Pathway

Novel One-Pot Total Syntheses of Deoxyvasicinone, Mackinazolinone, Isaindigotone, and Their Derivatives Promoted by Microwave Irradiation

Enhanced Secretory Production of a Single-Chain Antibody Fragment from Bacillus subtilis by Coproduction of Molecular Chaperones

Rapid Colchicine Competition-Binding Scintillation Proximity Assay Using Biotin-Labeled Tubulin

Biological Activity of A-289099: An Orally Active Tubulin-binding Indolyloxazoline Derivative

Crystal structure of HsEg5 in complex with clinical candidate CK0238273 provides insight into inhibitory mechanism, potency, and specificity

NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP

Identification of Polymorphisms Associated with Hypertriglyceridemia and Prolonged Survival Induced by Bexarotene in Treating Non-small Cell Lung Cancer

Aryl tetrahydropyridine inhibitors of farnesyltransferase: glycine, phenylalanine and histidine derivatives

Crystal Structure and Mutagenic Analysis of the Inhibitor-of-Apoptosis Protein Survivin

Blocking CHK1 Expression Induces Apoptosis and Abrogates the G2 Checkpoint Mechanism

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