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Identification of a selective ERK inhibitor and structural determination of the inhibitor–ERK2 complex

Biochemical and biophysical research communications, 2005-10, Vol.336 (1), p.357-363

2005

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Identification of natural diterpenes that inhibit bacterial wilt disease in tobacco, tomato and Arabidopsis

Plant and cell physiology, 2012-08, Vol.53 (8), p.1432-1444

2012

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Sustained therapeutic benefits by transient reduction of TDP-43 using ENA-modified antisense oligonucleotides in ALS/FTD mice

Molecular therapy. Nucleic acids, 2023-03, Vol.31, p.353-366

2023

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Prevention of progressive joint destruction in collagen‐induced arthritis in rats by a novel matrix metalloproteinase inhibitor, FR255031

British journal of pharmacology, 2005-01, Vol.144 (1), p.133-143

2005

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Design and Synthesis of DDR1 Inhibitors with a Desired Pharmacophore Using Deep Generative Models

ChemMedChem, 2021-03, Vol.16 (6), p.955-958

2021

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Discovery of ASP5286: A novel non-immunosuppressive cyclophilin inhibitor for the treatment of HCV

Bioorganic & medicinal chemistry letters, 2020-08, Vol.30 (16), p.127308-127308, Article 127308

2020

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Improving quality and harvest period of protein crystals for structure-based drug design: effects of a gel and a magnetic field on bovine adenosine deaminase crystals

Acta crystallographica. Section D, Biological crystallography., 2003-07, Vol.59 (7), p.1333-1335

2003

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Molecular Basis for Allosteric Inhibition of GTP-Bound H‑Ras Protein by a Small-Molecule Compound Carrying a Naphthalene Ring

Biochemistry (Easton), 2018-09, Vol.57 (36), p.5350-5358

2018

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Synthesis and structure activity relationships of glycine amide derivatives as novel Vascular Adhesion Protein-1 inhibitors

Bioorganic & medicinal chemistry, 2017-01, Vol.25 (1), p.187-201

2017

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Crystal structure of human ERK2 complexed with a pyrazolo[3,4- c]pyridazine derivative

Bioorganic & medicinal chemistry letters, 2006, Vol.16 (1), p.55-58

2006

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Prevention of progressive joint destruction in adjuvant induced arthritis in rats by a novel matrix metalloproteinase inhibitor, FR217840

European journal of pharmacology, 2005-01, Vol.508 (1), p.239-247

2005

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Synthesis of threo-3-Methylcysteine from Threonine

Bulletin of the Chemical Society of Japan, 1982-12, Vol.55 (12), p.3878-3881

1982

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Erratum to “Prevention of progressive joint destruction in adjuvant induced arthritis in rats by a novel matrix metalloproteinase inhibitor, FR217840” [Eur. J. of Pharmacol. 508 (2005) 239–247]

European journal of pharmacology, 2005-05, Vol.515 (1-3), p.188-188

2005

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Discovery of endothelin antagonists

Pure and applied chemistry, 1997-01, Vol.69 (3), p.441-446

Neya, M.

1997

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Studies on 2-Aziridinecarboxylic Acid. V. Formation of Dehydroamino Acid Containing Peptides via the Isomerization by NaI of 2-Aziridinecarboxylic Acid Containing Peptides

Bulletin of the Chemical Society of Japan, 1982-01, Vol.55 (1), p.174-176

1982

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Studies on 2-Aziridinecarboxylic Acid. VI. Synthesis of β-Alkoxy-α-Amino Acids via Ring-opening Reaction of Aziridine

Bulletin of the Chemical Society of Japan, 1982-09, Vol.55 (9), p.3049-3050

1982

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A novel and efficient method for cleavage of phenacyl esters by zinc reduction with acetylacetone and pyridine

Tetrahedron letters, 1990, Vol.31 (45), p.6539-6542

1990

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WS-7338, NEW ENDOTHELIN RECEPTOR ANTAGONISTS ISOLATED FROM Streptomyces sp. No. 7338: III. STRUCTURES OF WS-7338 A, B, C AND D AND TOTAL SYNTHESIS OF WS-7338 B

The Journal of Antibiotics, 1992/05/25, Vol.45(5), pp.788-791

1992

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Studies on 2-Aziridinecarboxylic Acid. VIII. Total Synthesis of Actinomycin D and Its Serine Analogue via Ring-opening Reaction of 1-Benzyloxycarbonyl-2-aziridinecarboxylic Acid Moiety

Bulletin of the Chemical Society of Japan, 1982-10, Vol.55 (10), p.3237-3241

1982

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Total synthesis of urogastrone (human epidermal growth factor, h-EGF)

Journal of the Chemical Society. Chemical communications, 1984 (24), p.1676-1678

1984

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Surgical treatments for infective endocarditis involving valve annulus

Annals of thoracic and cardiovascular surgery, 2009-12, Vol.15 (6), p.378-381

2009

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MS31

Nihon Kesshō Gakkaishi, 2009, Vol.51 (1), p.59-64

2009

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Identification of a selective ERK inhibitor and structural determination of the inhibitor–ERK2 complex

Identification of natural diterpenes that inhibit bacterial wilt disease in tobacco, tomato and Arabidopsis

Sustained therapeutic benefits by transient reduction of TDP-43 using ENA-modified antisense oligonucleotides in ALS/FTD mice

Prevention of progressive joint destruction in collagen‐induced arthritis in rats by a novel matrix metalloproteinase inhibitor, FR255031

Design and Synthesis of DDR1 Inhibitors with a Desired Pharmacophore Using Deep Generative Models

Discovery of ASP5286: A novel non-immunosuppressive cyclophilin inhibitor for the treatment of HCV

Improving quality and harvest period of protein crystals for structure-based drug design: effects of a gel and a magnetic field on bovine adenosine deaminase crystals

Molecular Basis for Allosteric Inhibition of GTP-Bound H‑Ras Protein by a Small-Molecule Compound Carrying a Naphthalene Ring

Synthesis and structure activity relationships of glycine amide derivatives as novel Vascular Adhesion Protein-1 inhibitors

Crystal structure of human ERK2 complexed with a pyrazolo[3,4- c]pyridazine derivative

Prevention of progressive joint destruction in adjuvant induced arthritis in rats by a novel matrix metalloproteinase inhibitor, FR217840

Synthesis of threo-3-Methylcysteine from Threonine

Erratum to “Prevention of progressive joint destruction in adjuvant induced arthritis in rats by a novel matrix metalloproteinase inhibitor, FR217840” [Eur. J. of Pharmacol. 508 (2005) 239–247]

Discovery of endothelin antagonists

Studies on 2-Aziridinecarboxylic Acid. V. Formation of Dehydroamino Acid Containing Peptides via the Isomerization by NaI of 2-Aziridinecarboxylic Acid Containing Peptides

Studies on 2-Aziridinecarboxylic Acid. VI. Synthesis of β-Alkoxy-α-Amino Acids via Ring-opening Reaction of Aziridine

A novel and efficient method for cleavage of phenacyl esters by zinc reduction with acetylacetone and pyridine

WS-7338, NEW ENDOTHELIN RECEPTOR ANTAGONISTS ISOLATED FROM Streptomyces sp. No. 7338: III. STRUCTURES OF WS-7338 A, B, C AND D AND TOTAL SYNTHESIS OF WS-7338 B

Studies on 2-Aziridinecarboxylic Acid. VIII. Total Synthesis of Actinomycin D and Its Serine Analogue via Ring-opening Reaction of 1-Benzyloxycarbonyl-2-aziridinecarboxylic Acid Moiety

Total synthesis of urogastrone (human epidermal growth factor, h-EGF)

Surgical treatments for infective endocarditis involving valve annulus

MS31

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