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Evaluating Climate Change Impacts

1st edition, 2020

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Conformational Preferences in a Benzodiazepine Series of Potent Nonpeptide Fibrinogen Receptor Antagonists

Journal of medicinal chemistry, 1999-02, Vol.42 (4), p.545-559

1999

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Preclinical pharmacokinetics and interspecies scaling of a novel vitronectin receptor antagonist

Drug metabolism and disposition, 1999-11, Vol.27 (11), p.1232

1999

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Potent, Selective, Orally Active 3-Oxo-1,4-benzodiazepine GPIIb/IIIa Integrin Antagonists

Journal of medicinal chemistry, 1996-12, Vol.39 (25), p.4867-4870

1996

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Genetic basis for susceptibility to noise-induced hearing loss in mice

Hearing research, 2001-05, Vol.155 (1), p.82-90

2001

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Inhibitors of bacterial enoyl acyl carrier protein reductase (FabI): 2,9-disubstituted 1,2,3,4-tetrahydropyrido[3,4- b]indoles as potential antibacterial agents

Bioorganic & medicinal chemistry letters, 2001-09, Vol.11 (17), p.2241-2244

2001

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Design and characterization of orally active Arg-Gly-Asp peptidomimetic vitronectin receptor antagonist SB 265123 for prevention of bone loss in osteoporosis

The Journal of pharmacology and experimental therapeutics, 1999-11, Vol.291 (2), p.612

1999

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A Check on Rational Drug Design: Crystal Structure of a Complex of Human Immunodeficiency Virus Type 1 Protease with a Novel .gamma.-Turn Mimetic Inhibitor

Journal of medicinal chemistry, 1995-08, Vol.38 (17), p.3246-3252

1995

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Orally bioavailable nonpeptide vitronectin receptor antagonists with efficacy in an osteoporosis model

Bioorganic & medicinal chemistry letters, 1999-07, Vol.9 (13), p.1807-1812

1999

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A novel constrained reduced-amide inhibitor of HIV-1 protease derived from the sequential incorporation of .gamma.-turn mimetics into a model substrate

Journal of medicinal chemistry, 1993-08, Vol.36 (16), p.2321-2331

1993

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Density profile of blue-sensitive cones along the horizontal meridian of macaque retina

Investigative ophthalmology & visual science, 1985-03, Vol.26 (3), p.289-302

1985

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Conformational energy studies and in vitro and in vivo activity data on growth hormone-releasing peptides

Endocrinology (Philadelphia), 1984-05, Vol.114 (5), p.1531-1536

1984

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Indole Naphthyridinones as Inhibitors of Bacterial Enoyl-ACP Reductases FabI and FabK

Journal of medicinal chemistry, 2003-04, Vol.46 (9), p.1627-1635

2003

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Design, synthesis, and biological activity of peptides which release growth hormone in vitro

Endocrinology (Philadelphia), 1981-01, Vol.108 (1), p.31-39

1981

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Defining and Combating the Mechanisms of Triclosan Resistance in Clinical Isolates of Staphylococcus aureus

Antimicrobial Agents and Chemotherapy, 2002-11, Vol.46 (11), p.3343-3347

2002

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Discovery of Aminopyridine-Based Inhibitors of Bacterial Enoyl-ACP Reductase (FabI)

Journal of medicinal chemistry, 2002-07, Vol.45 (15), p.3246-3256

2002

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Dicarbavasopressin antagonist analogs exhibit reduced in vivo agonist activity

Journal of medicinal chemistry, 1988-08, Vol.31 (8), p.1487-1489

1988

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A minor modification of residue 1 in potent vasopressin antagonists dramatically reduces agonist activity

Journal of medicinal chemistry, 1989-04, Vol.32 (4), p.880-884

1989

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Direct design of a potent non-peptide fibrinogen receptor antagonist based on the structure and conformation of a highly constrained cyclic RGD peptide

Journal of the American Chemical Society, 1993-09, Vol.115 (19), p.8861-8862

1993

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A Facile and Versatile Synthesis of 2-Substituted Tryptophans as Nα-tert- Butyloxycarbonyl Derivatives

Synthesis (Stuttgart), 1988, Vol.1988 (1), p.73-76

1988

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Simple Silyl Linker for the Solid Phase Organic Synthesis of Aryl- Containing Molecules

Journal of organic chemistry, 1997-10, Vol.62 (20), p.6726-6732

1997

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Synthesis of 6,6-pentamethylene-2-aminosuberic acid. A key intermediate in the synthesis of dicarba analogs of vasopressin antagonists

Journal of organic chemistry, 1988-04, Vol.53 (7), p.1527-1530

1988

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Enantiospecific synthesis of SB 214857, a potent, orally active, nonpeptide fibrinogen receptor antagonist

Tetrahedron letters, 1995-12, Vol.36 (52), p.9433-9436

1995

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Effect of Bicarbonate-free Balanced Salt Solutions on Fluid Pump and Endothelial Morphology of Rabbit Corneas In-vitro

Journal of pharmacy and pharmacology, 1993-02, Vol.45 (2), p.102-109

1993

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Evaluating Climate Change Impacts

Conformational Preferences in a Benzodiazepine Series of Potent Nonpeptide Fibrinogen Receptor Antagonists

Preclinical pharmacokinetics and interspecies scaling of a novel vitronectin receptor antagonist

Potent, Selective, Orally Active 3-Oxo-1,4-benzodiazepine GPIIb/IIIa Integrin Antagonists

Genetic basis for susceptibility to noise-induced hearing loss in mice

Inhibitors of bacterial enoyl acyl carrier protein reductase (FabI): 2,9-disubstituted 1,2,3,4-tetrahydropyrido[3,4- b]indoles as potential antibacterial agents

Design and characterization of orally active Arg-Gly-Asp peptidomimetic vitronectin receptor antagonist SB 265123 for prevention of bone loss in osteoporosis

A Check on Rational Drug Design: Crystal Structure of a Complex of Human Immunodeficiency Virus Type 1 Protease with a Novel .gamma.-Turn Mimetic Inhibitor

Orally bioavailable nonpeptide vitronectin receptor antagonists with efficacy in an osteoporosis model

A novel constrained reduced-amide inhibitor of HIV-1 protease derived from the sequential incorporation of .gamma.-turn mimetics into a model substrate

Density profile of blue-sensitive cones along the horizontal meridian of macaque retina

Discovery of Orally Active Nonpeptide Vitronectin Receptor Antagonists Based on a 2-Benzazepine Gly-Asp Mimetic

Conformational energy studies and in vitro and in vivo activity data on growth hormone-releasing peptides

Indole Naphthyridinones as Inhibitors of Bacterial Enoyl-ACP Reductases FabI and FabK

Design, synthesis, and biological activity of peptides which release growth hormone in vitro

Defining and Combating the Mechanisms of Triclosan Resistance in Clinical Isolates of Staphylococcus aureus

Discovery of Aminopyridine-Based Inhibitors of Bacterial Enoyl-ACP Reductase (FabI)

Dicarbavasopressin antagonist analogs exhibit reduced in vivo agonist activity

A minor modification of residue 1 in potent vasopressin antagonists dramatically reduces agonist activity

Direct design of a potent non-peptide fibrinogen receptor antagonist based on the structure and conformation of a highly constrained cyclic RGD peptide

A Facile and Versatile Synthesis of 2-Substituted Tryptophans as Nα-tert- Butyloxycarbonyl Derivatives

Simple Silyl Linker for the Solid Phase Organic Synthesis of Aryl- Containing Molecules

Synthesis of 6,6-pentamethylene-2-aminosuberic acid. A key intermediate in the synthesis of dicarba analogs of vasopressin antagonists

Enantiospecific synthesis of SB 214857, a potent, orally active, nonpeptide fibrinogen receptor antagonist

Effect of Bicarbonate-free Balanced Salt Solutions on Fluid Pump and Endothelial Morphology of Rabbit Corneas In-vitro

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