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HIF-1α Regulates Radiation Resistance in Primary Sarcomas in a Tumor-Cell Autonomous Mechanism

International journal of radiation oncology, biology, physics, 2014-09, Vol.90 (1), p.S772-S772

2014

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Overexpression of hexokinase I in isolated islets of Langerhans via recombinant adenovirus. Enhancement of glucose metabolism and insulin secretion at basal but not stimulatory glucose levels

The Journal of biological chemistry, 1994-08, Vol.269 (33), p.21234-21238

1994

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Transfection of AtT-20ins cells with GLUT-2 but not GLUT-1 confers glucose-stimulated insulin secretion: relationship to glucose metabolism

The Journal of biological chemistry, 1993-07, Vol.268 (20), p.15205-15212

1993

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Unique metabolic profile in children with Prader-Willi Syndrome: Heightened insulin sensitivity relative to body mass index

Canadian journal of diabetes, 2011, Vol.35 (2), p.145-145

2011

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GLUT-2 gene transfer into insulinoma cells confers both low and high affinity glucose-stimulated insulin release: relationship to glucokinase activity

The Journal of biological chemistry, 1994-04, Vol.269 (15), p.11523-11529

1994

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Comparison of proteomic and metabolomic profiles of mutants of the mitochondrial respiratory chain in Caenorhabditis elegans

Mitochondrion, 2015-01, Vol.20, p.95-102

2015

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Direct antidiabetic effect of leptin through triglyceride depletion of tissues

Proceedings of the National Academy of Sciences - PNAS, 1997-04, Vol.94 (9), p.4637-4641

1997

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Lipoapoptosis in beta-cells of obese prediabetic fa/fa rats. Role of serine palmitoyltransferase overexpression

The Journal of biological chemistry, 1998-12, Vol.273 (49), p.32487

1998

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Reversing adipocyte differentiation: implications for treatment of obesity

Proceedings of the National Academy of Sciences - PNAS, 1999-03, Vol.96 (5), p.2391-2395

1999

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Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expression

Proceedings of the National Academy of Sciences - PNAS, 1998-08, Vol.95 (16), p.9558-9561

1998

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Disappearance of body fat in normal rats induced by adenovirus-mediated leptin gene therapy

Proceedings of the National Academy of Sciences - PNAS, 1996-12, Vol.93 (25), p.14795-14799

1996

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Perturbation of Fuel Homeostasis Caused by Overexpression of the Glucose-6-phosphatase Catalytic Subunit in Liver of Normal Rats

The Journal of biological chemistry, 1998-11, Vol.273 (47), p.31615-31620

1998

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Inflammatory mechanisms in diabetes: lessons from the β-cell

International Journal of Obesity, 2003-12, Vol.27 (3), p.S12-S16

2003

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Role of peroxisome proliferator-activated receptor alpha in disease of pancreatic beta cells

Proceedings of the National Academy of Sciences - PNAS, 1998-07, Vol.95 (15), p.8898-8903

1998

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OB-Rb gene transfer to leptin-resistant islets reverses diabetogenic phenotype

Proceedings of the National Academy of Sciences - PNAS, 1998-01, Vol.95 (2), p.714-718

1998

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Overexpression of leptin receptors in pancreatic islets of Zucker diabetic fatty rats restores GLUT-2, glucokinase, and glucose-stimulated insulin secretion

Proceedings of the National Academy of Sciences - PNAS, 1998-09, Vol.95 (20), p.11921-11926

1998

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Adenovirus-mediated transfer of the muscle glycogen phosphorylase gene into hepatocytes confers altered regulation of glycogen metabolism

The Journal of biological chemistry, 1992-12, Vol.267 (35), p.25129-25134

1992

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21 - Unique metabolic profile in children with Prader-Willi Syndrome: Heightened insulin sensitivity relative to body mass index

Canadian journal of diabetes, 2011, Vol.35 (2), p.145-145

2011

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Engineering of glycerol-stimulated insulin secretion in islet beta cells. Differential metabolic fates of glucose and glycerol provide insight into mechanisms of stimulus-secretion coupling

The Journal of biological chemistry, 1997-07, Vol.272 (30), p.18621

1997

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Glucokinase Overexpression Restores Glucose Utilization and Storage in Cultured Hepatocytes from Male Zucker Diabetic Fatty Rats

The Journal of biological chemistry, 1999-11, Vol.274 (45), p.31833-31838

1999

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Evidence that Down-Regulation of β-Cell Glucose Transporters in Non-Insulin-Dependent Diabetes May be the Cause of Diabetic Hyperglycemia

Proceedings of the National Academy of Sciences - PNAS, 1990-12, Vol.87 (24), p.9953-9957

1990

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Metabolic engineering with recombinant adenoviruses

Annual review of nutrition, 1999-01, Vol.19 (1), p.511-544

1999

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Sparing effect of leptin on liver glycogen stores in rats during the fed-to-fasted transition

American journal of physiology: endocrinology and metabolism, 1999-09, Vol.277 (3), p.E544-E550

1999

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Regulation of β-Cell Glucose Transporter Gene Expression

Proceedings of the National Academy of Sciences - PNAS, 1990-06, Vol.87 (11), p.4088-4092

1990

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Cellular Engineering for the Treatment of Metabolic Disorders: Prospects for Therapy in Diabetes

Bio/technology (New York, N.Y. 1983), 1992-10, Vol.10 (10), p.1112-1120

Newgard, Christopher B

1992

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HIF-1α Regulates Radiation Resistance in Primary Sarcomas in a Tumor-Cell Autonomous Mechanism

Overexpression of hexokinase I in isolated islets of Langerhans via recombinant adenovirus. Enhancement of glucose metabolism and insulin secretion at basal but not stimulatory glucose levels

Transfection of AtT-20ins cells with GLUT-2 but not GLUT-1 confers glucose-stimulated insulin secretion: relationship to glucose metabolism

Unique metabolic profile in children with Prader-Willi Syndrome: Heightened insulin sensitivity relative to body mass index

GLUT-2 gene transfer into insulinoma cells confers both low and high affinity glucose-stimulated insulin release: relationship to glucokinase activity

Comparison of proteomic and metabolomic profiles of mutants of the mitochondrial respiratory chain in Caenorhabditis elegans

Direct antidiabetic effect of leptin through triglyceride depletion of tissues

Lipoapoptosis in beta-cells of obese prediabetic fa/fa rats. Role of serine palmitoyltransferase overexpression

Reversing adipocyte differentiation: implications for treatment of obesity

Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expression

Disappearance of body fat in normal rats induced by adenovirus-mediated leptin gene therapy

Perturbation of Fuel Homeostasis Caused by Overexpression of the Glucose-6-phosphatase Catalytic Subunit in Liver of Normal Rats

Inflammatory mechanisms in diabetes: lessons from the β-cell

Role of peroxisome proliferator-activated receptor alpha in disease of pancreatic beta cells

OB-Rb gene transfer to leptin-resistant islets reverses diabetogenic phenotype

Overexpression of leptin receptors in pancreatic islets of Zucker diabetic fatty rats restores GLUT-2, glucokinase, and glucose-stimulated insulin secretion

Adenovirus-mediated transfer of the muscle glycogen phosphorylase gene into hepatocytes confers altered regulation of glycogen metabolism

21 - Unique metabolic profile in children with Prader-Willi Syndrome: Heightened insulin sensitivity relative to body mass index

Engineering of glycerol-stimulated insulin secretion in islet beta cells. Differential metabolic fates of glucose and glycerol provide insight into mechanisms of stimulus-secretion coupling

Glucokinase Overexpression Restores Glucose Utilization and Storage in Cultured Hepatocytes from Male Zucker Diabetic Fatty Rats

Evidence that Down-Regulation of β-Cell Glucose Transporters in Non-Insulin-Dependent Diabetes May be the Cause of Diabetic Hyperglycemia

Metabolic engineering with recombinant adenoviruses

Sparing effect of leptin on liver glycogen stores in rats during the fed-to-fasted transition

Regulation of β-Cell Glucose Transporter Gene Expression

Cellular Engineering for the Treatment of Metabolic Disorders: Prospects for Therapy in Diabetes

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