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Metalloproteinase production from macrophages – a perfect storm leading to atherosclerotic plaque rupture and myocardial infarction

Experimental physiology, 2016-11, Vol.101 (11), p.1327-1337

Newby, Andrew C.

2016

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Metalloproteinase expression in monocytes and macrophages and its relationship to atherosclerotic plaque instability

Arteriosclerosis, thrombosis, and vascular biology, 2008-12, Vol.28 (12), p.2108-2114

Newby, Andrew C

2008

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Matrix metalloproteinase inhibition therapy for vascular diseases

Vascular pharmacology, 2012-05, Vol.56 (5), p.232-244

Newby, Andrew C

2012

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Dual Role of Matrix Metalloproteinases (Matrixins) in Intimal Thickening and Atherosclerotic Plaque Rupture

Physiological reviews, 2005-01, Vol.85 (1), p.1-31

Newby, Andrew C

2005

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MicroRNA-181b Controls Atherosclerosis and Aneurysms Through Regulation of TIMP-3 and Elastin

Circulation research, 2017-01, Vol.120 (1), p.49-65

2017

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Endothelial erosion of plaques as a substrate for coronary thrombosis

Thrombosis and haemostasis, 2016-03, Vol.115 (3), p.509-519

2016

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Classical macrophage activation up-regulates several matrix metalloproteinases through mitogen activated protein kinases and nuclear factor-κB

PloS one, 2012-08, Vol.7 (8), p.e42507

2012

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MicroRNA-24 regulates macrophage behavior and retards atherosclerosis

Arteriosclerosis, thrombosis, and vascular biology, 2014-09, Vol.34 (9), p.1990-2000

2014

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Antiproliferative and Antimigratory Effects of a Novel YAP–TEAD Interaction Inhibitor Identified Using in Silico Molecular Docking

Journal of medicinal chemistry, 2019-02, Vol.62 (3), p.1291-1305

2019

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The Hippo pathway mediates inhibition of vascular smooth muscle cell proliferation by cAMP

Journal of molecular and cellular cardiology, 2016-01, Vol.90, p.1-10

2016

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Vulnerable atherosclerotic plaque metalloproteinases and foam cell phenotypes

Thrombosis and haemostasis, 2009-06, Vol.101 (6), p.1006-1011

2009

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Matrix metalloproteinase (MMP)-3 activates MMP-9 mediated vascular smooth muscle cell migration and neointima formation in mice

Arteriosclerosis, thrombosis, and vascular biology, 2011-09, Vol.31 (9), p.e35

2011

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Differential effects of tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2 on atherosclerosis and monocyte/macrophage invasion

Cardiovascular research, 2016-02, Vol.109 (2), p.318-330

2016

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Ending Restenosis: Inhibition of Vascular Smooth Muscle Cell Proliferation by cAMP

Cells (Basel, Switzerland), 2019-11, Vol.8 (11), p.1447

2019

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Foam Cell Formation In Vivo Converts Macrophages to a Pro-Fibrotic Phenotype

PloS one, 2015-07, Vol.10 (7), p.e0128163-e0128163

2015

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Metalloproteinases promote plaque rupture and myocardial infarction: A persuasive concept waiting for clinical translation

Matrix biology, 2015-05, Vol.44-46, p.157-166

Newby, Andrew C.

2015

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A selective matrix metalloproteinase-12 inhibitor retards atherosclerotic plaque development in apolipoprotein E-knockout mice

Arteriosclerosis, thrombosis, and vascular biology, 2011-03, Vol.31 (3), p.528-535

2011

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Divergent Effects of Matrix Metalloproteinases 3, 7, 9, and 12 on Atherosclerotic Plaque Stability in Mouse Brachiocephalic Arteries

Proceedings of the National Academy of Sciences - PNAS, 2005-10, Vol.102 (43), p.15575-15580

2005

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PKA and Epac synergistically inhibit smooth muscle cell proliferation

Journal of molecular and cellular cardiology, 2011-01, Vol.50 (1), p.87-98

2011

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Characterization of the differential response of endothelial cells exposed to normal and elevated laminar shear stress

Journal of cellular physiology, 2011-11, Vol.226 (11), p.2841-2848

2011

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Divergent Regulation of Actin Dynamics and Megakaryoblastic Leukemia-1 and -2 (Mkl1/2) by cAMP in Endothelial and Smooth Muscle Cells

Scientific reports, 2017-06, Vol.7 (1), p.3681-13, Article 3681

2017

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Statins inhibit secretion of metalloproteinases-1, -2, -3, and -9 from vascular smooth muscle cells and macrophages

Arteriosclerosis, thrombosis, and vascular biology, 2003-05, Vol.23 (5), p.769-775

2003

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Relationship of MMP-14 and TIMP-3 Expression with Macrophage Activation and Human Atherosclerotic Plaque Vulnerability

Mediators of Inflammation, 2014-01, Vol.2014 (2), p.395-411

2014

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Effects of adenosine on lymphangiogenesis

PloS one, 2014-03, Vol.9 (3), p.e92715-e92715

2014

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Matrix metalloproteinases regulate migration, proliferation, and death of vascular smooth muscle cells by degrading matrix and non-matrix substrates

Cardiovascular research, 2006-02, Vol.69 (3), p.614-624

NEWBY, Andrew C

2006

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Metalloproteinase production from macrophages – a perfect storm leading to atherosclerotic plaque rupture and myocardial infarction

Metalloproteinase expression in monocytes and macrophages and its relationship to atherosclerotic plaque instability

Matrix metalloproteinase inhibition therapy for vascular diseases

Dual Role of Matrix Metalloproteinases (Matrixins) in Intimal Thickening and Atherosclerotic Plaque Rupture

MicroRNA-181b Controls Atherosclerosis and Aneurysms Through Regulation of TIMP-3 and Elastin

Endothelial erosion of plaques as a substrate for coronary thrombosis

Classical macrophage activation up-regulates several matrix metalloproteinases through mitogen activated protein kinases and nuclear factor-κB

MicroRNA-24 regulates macrophage behavior and retards atherosclerosis

Antiproliferative and Antimigratory Effects of a Novel YAP–TEAD Interaction Inhibitor Identified Using in Silico Molecular Docking

The Hippo pathway mediates inhibition of vascular smooth muscle cell proliferation by cAMP

Vulnerable atherosclerotic plaque metalloproteinases and foam cell phenotypes

Matrix metalloproteinase (MMP)-3 activates MMP-9 mediated vascular smooth muscle cell migration and neointima formation in mice

Differential effects of tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2 on atherosclerosis and monocyte/macrophage invasion

Ending Restenosis: Inhibition of Vascular Smooth Muscle Cell Proliferation by cAMP

Foam Cell Formation In Vivo Converts Macrophages to a Pro-Fibrotic Phenotype

Metalloproteinases promote plaque rupture and myocardial infarction: A persuasive concept waiting for clinical translation

A selective matrix metalloproteinase-12 inhibitor retards atherosclerotic plaque development in apolipoprotein E-knockout mice

Divergent Effects of Matrix Metalloproteinases 3, 7, 9, and 12 on Atherosclerotic Plaque Stability in Mouse Brachiocephalic Arteries

PKA and Epac synergistically inhibit smooth muscle cell proliferation

Characterization of the differential response of endothelial cells exposed to normal and elevated laminar shear stress

Divergent Regulation of Actin Dynamics and Megakaryoblastic Leukemia-1 and -2 (Mkl1/2) by cAMP in Endothelial and Smooth Muscle Cells

Statins inhibit secretion of metalloproteinases-1, -2, -3, and -9 from vascular smooth muscle cells and macrophages

Relationship of MMP-14 and TIMP-3 Expression with Macrophage Activation and Human Atherosclerotic Plaque Vulnerability

Effects of adenosine on lymphangiogenesis

Matrix metalloproteinases regulate migration, proliferation, and death of vascular smooth muscle cells by degrading matrix and non-matrix substrates

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