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Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activity

Molecular cancer therapeutics, 2005-10, Vol.4 (10), p.1521-1532

2005

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Structure of the Epigenetic Oncogene MMSET and Inhibition by N‑Alkyl Sinefungin Derivatives

ACS chemical biology, 2016-11, Vol.11 (11), p.3093-3105

2016

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The phosphoinositide-specific phospholipase C inhibitor U73122 (1-(6-((17beta-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione) spontaneously forms conjugates with common components of cell culture medium

Drug metabolism and disposition, 2007-07, Vol.35 (7), p.1017-1022

2007

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Identification of autophosphorylation inhibitors of the inositol-requiring enzyme 1 alpha (IRE1α) by high-throughput screening using a DELFIA assay

Journal of biomolecular screening, 2013-03, Vol.18 (3), p.298-308

2013

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AMPK-independent inhibition of human macrophage ER stress response by AICAR

Scientific reports, 2016-08, Vol.6 (1), p.32111-32111, Article 32111

2016

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Binding to an Unusual Inactive Kinase Conformation by Highly Selective Inhibitors of Inositol-Requiring Enzyme 1α Kinase-Endoribonuclease

Journal of medicinal chemistry, 2019-03, Vol.62 (5), p.2447-2465

2019

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Molecular mechanisms of human IRE1 activation through dimerization and ligand binding

Oncotarget, 2015-05, Vol.6 (15), p.13019-13035

2015

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Evaluation of APOBEC3B Recognition Motifs by NMR Reveals Preferred Substrates

ACS chemical biology, 2018-09, Vol.13 (9), p.2427-2432

2018

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Multiple autophosphorylations significantly enhance the endoribonuclease activity of human inositol requiring enzyme 1α

BMC biochemistry, 2014-02, Vol.15 (1), p.3-3, Article 3

2014

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Identification by High-Throughput Screening of Viridin Analogs as Biochemical and Cell-Based Inhibitors of the Cell Cycle–Regulated Nek2 Kinase

Journal of biomolecular screening, 2010-09, Vol.15 (8), p.918-927

2010

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Identification of Small-Molecule Inhibitors of Protein Kinase B (PKB/AKT) in an AlphaScreen™ High-Throughput Screen

SLAS discovery, 2006-10, Vol.11 (7), p.822-827

2006

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High-Throughput Screening for Identification of Small Molecule Inhibitors of Histone Acetyltransferases Using Scintillating Microplates (FlashPlate)

Analytical biochemistry, 2001-11, Vol.298 (1), p.62-68

2001

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Multiple autophosphorylations significantly enhance the endoribonuclease activity of human inositol requiring enzyme 1[alpha]

BMC biochemistry, 2014-01, Vol.15

2014

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High-throughput screening assay for identification of small molecule inhibitors of Aurora2/STK15 kinase

Journal of biomolecular screening, 2004-08, Vol.9 (5), p.391-397

2004

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Structural and mechanistic aspects of phospholipase Cγ regulation

Advances in enzyme regulation, 2003-01, Vol.43 (1), p.77-85

2003

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Identification of Inhibitors of the Kinase Activity of Oncogenic V600EBRAF in an Enzyme Cascade High-Throughput Screen

SLAS discovery, 2006-03, Vol.11 (2), p.145-154

2006

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Identification of small-molecule inhibitors of protein kinase B (PKB/AKT) in an AlphaScreenTM high-throughput screen

Journal of biomolecular screening, 2006-10, Vol.11 (7), p.822

2006

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Identification of inhibitors of the kinase activity of oncogenic V600E BRAF in an enzyme cascade high-throughput screen

Journal of biomolecular screening, 2006-03, Vol.11 (2), p.145

2006

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Structural and mechanistic aspects of phospholipase Cgamma regulation

Advances in enzyme regulation, 2003, Vol.43, p.77-85

2003

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Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activity

Structure of the Epigenetic Oncogene MMSET and Inhibition by N‑Alkyl Sinefungin Derivatives

The phosphoinositide-specific phospholipase C inhibitor U73122 (1-(6-((17beta-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione) spontaneously forms conjugates with common components of cell culture medium

Identification of autophosphorylation inhibitors of the inositol-requiring enzyme 1 alpha (IRE1α) by high-throughput screening using a DELFIA assay

AMPK-independent inhibition of human macrophage ER stress response by AICAR

Binding to an Unusual Inactive Kinase Conformation by Highly Selective Inhibitors of Inositol-Requiring Enzyme 1α Kinase-Endoribonuclease

Molecular mechanisms of human IRE1 activation through dimerization and ligand binding

Evaluation of APOBEC3B Recognition Motifs by NMR Reveals Preferred Substrates

Multiple autophosphorylations significantly enhance the endoribonuclease activity of human inositol requiring enzyme 1α

Identification by High-Throughput Screening of Viridin Analogs as Biochemical and Cell-Based Inhibitors of the Cell Cycle–Regulated Nek2 Kinase

Identification of Small-Molecule Inhibitors of Protein Kinase B (PKB/AKT) in an AlphaScreen™ High-Throughput Screen

High-Throughput Screening for Identification of Small Molecule Inhibitors of Histone Acetyltransferases Using Scintillating Microplates (FlashPlate)

Multiple autophosphorylations significantly enhance the endoribonuclease activity of human inositol requiring enzyme 1[alpha]

High-throughput screening assay for identification of small molecule inhibitors of Aurora2/STK15 kinase

Structural and mechanistic aspects of phospholipase Cγ regulation

Identification of Inhibitors of the Kinase Activity of Oncogenic V600EBRAF in an Enzyme Cascade High-Throughput Screen

Identification of small-molecule inhibitors of protein kinase B (PKB/AKT) in an AlphaScreenTM high-throughput screen

Identification of inhibitors of the kinase activity of oncogenic V600E BRAF in an enzyme cascade high-throughput screen

Structural and mechanistic aspects of phospholipase Cgamma regulation

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