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Novel indole and azaindole (pyrrolopyridine) cannabinoid (CB) receptor agonists: Design, synthesis, structure–activity relationships, physicochemical properties and biological activity

European journal of medicinal chemistry, 2011-10, Vol.46 (10), p.5086-5098

2011

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Design, Synthesis, Biological Properties, and Molecular Modeling Investigations of Novel Tacrine Derivatives with a Combination of Acetylcholinesterase Inhibition and Cannabinoid CB1 Receptor Antagonism

Journal of medicinal chemistry, 2010-02, Vol.53 (3), p.1338-1346

2010

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N′-(Arylsulfonyl)pyrazoline-1-carboxamidines as Novel, Neutral 5-Hydroxytryptamine 6 Receptor (5-HT6R) Antagonists with Unique Structural Features

Journal of medicinal chemistry, 2011-10, Vol.54 (20), p.7030-7054

2011

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Synthesis and SAR of 1,4,5,6-tetrahydropyridazines as potent cannabinoid CB1 receptor antagonists

Bioorganic & medicinal chemistry letters, 2009-10, Vol.19 (19), p.5675-5678

2009

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Two distinct classes of novel pyrazolinecarboxamides as potent cannabinoid CB1 receptor agonists

Bioorganic & medicinal chemistry letters, 2010-09, Vol.20 (17), p.4992-4998

2010

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Synthesis and SAR of novel imidazoles as potent and selective cannabinoid CB2 receptor antagonists with high binding efficiencies

Bioorganic & medicinal chemistry letters, 2010-02, Vol.20 (3), p.1084-1089

2010

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Probing the cannabinoid CB1/CB2 receptor subtype selectivity limits of 1,2-diarylimidazole-4-carboxamides by fine-tuning their 5-substitution pattern

Bioorganic & medicinal chemistry letters, 2010-05, Vol.20 (9), p.2770-2775

2010

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The selective 5-HT6 receptor antagonist SLV has putative cognitive- and social interaction enhancing properties in rodent models of cognitive impairment

Neurobiology of learning and memory, 2016-09, Vol.133, p.100-117

2016

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Spatially resolved generation profiles for onshore and offshore wind turbines: A case study of four Dutch energy transition scenarios

Renewable and sustainable energy transition, 2022-08, Vol.2, p.100037, Article 100037

2022

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Development and application of an LC–MS/MS method for measuring the effect of (partial) agonists on cAMP accumulation in vitro

Journal of neuroscience methods, 2010-04, Vol.188 (1), p.24-31

2010

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Optimization of N′-(arylsulfonyl)pyrazoline-1-carboxamidines by exploiting a novel interaction site in the 5-HT6 antagonistic binding pocket

Bioorganic & medicinal chemistry letters, 2016-03, Vol.26 (6), p.1605-1611

2016

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The Association of Shelter Veterinarians veterinary medical care guidelines for spay-neuter programs

Journal of the American Veterinary Medical Association, 2008-07, Vol.233 (1), p.74

2008

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Synthesis, SAR and intramolecular hydrogen bonding pattern of 1,3,5-trisubstituted 4,5-dihydropyrazoles as potent cannabinoid CB1 receptor antagonists

Bioorganic & medicinal chemistry letters, 2010-03, Vol.20 (5), p.1752-1757

2010

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Spatially resolved generation profiles for building, land and water-bound PV: a case study of four Dutch energy transition scenarios

Advances in geosciences, 2023-07, Vol.58, p.199-216

2023

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Numerical Simulation and P arameter Optimization of the Inside In take and Outside Pressing Particle Collector

Journal of engineering science and technology review, 2015-06, Vol.8 (3), p.174-178

2015

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Lectotypification and Description of Clematis orientalis L. (Ranunculaceae)

Taxon, 1987-02, Vol.36 (1), p.117-126

1987

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Design, Synthesis, Biological Properties, and Molecular Modeling Investigations of Novel Tacrine Derivatives with a Combination of Acetylcholinesterase Inhibition and Cannabinoid CB 1 Receptor Antagonism

Journal of medicinal chemistry, 2010-02, Vol.53 (3), p.1338-1346

2010

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Optimization of N'-(arylsulfonyl)pyrazoline-1-carboxamidines by exploiting a novel interaction site in the 5-HT sub(6) antagonistic binding pocket

Bioorganic & medicinal chemistry letters, 2016-03, Vol.26 (6), p.1605-1611

2016

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Characterization of cytoplasmic male sterility in Petunia hybrida and Zea mays. Localization and activity of cytochrome c oxidase

Euphytica, 1986-11, Vol.35 (3), p.905-918

1986

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Synthesis and SAR of 1,4,5,6-tetrahydropyridazines as potent cannabinoid CB sub(1) receptor antagonists

Bioorganic & medicinal chemistry letters, 2009-10, Vol.19 (19), p.5675-5678

2009

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Probing the cannabinoid CB sub(1)/CB sub(2) receptor subtype selectivity limits of 1,2-diarylimidazole-4-carboxamides by fine-tuning their 5-substitution pattern

Bioorganic & medicinal chemistry letters, 2010-05, Vol.20 (9), p.2770-2775

2010

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Synthesis, SAR and intramolecular hydrogen bonding pattern of 1,3,5-trisubstituted 4,5-dihydropyrazoles as potent cannabinoid CB sub(1) receptor antagonists

Bioorganic & medicinal chemistry letters, 2010-03, Vol.20 (5), p.1752-1757

2010

Volltextzugriff (PDF)

Synthesis and SAR of novel imidazoles as potent and selective cannabinoid CB sub(2) receptor antagonists with high binding efficiencies

Bioorganic & medicinal chemistry letters, 2010-02, Vol.20 (3), p.1084-1089

2010

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The sensitivity of thin-walled compression members to column axis imperfection

International journal of solids and structures, 1973-08, Vol.9 (8), p.999-1011

Van Der Neut, A.

1973

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Synthesis, SAR and intramolecular hydrogen bonding pattern of 1,3,5-trisubstituted 4,5-dihydropyrazoles as potent cannabinoid CB(1) receptor antagonists

Bioorganic & medicinal chemistry letters, 2010-03, Vol.20 (5), p.1752-1757

2010

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Novel indole and azaindole (pyrrolopyridine) cannabinoid (CB) receptor agonists: Design, synthesis, structure–activity relationships, physicochemical properties and biological activity

Design, Synthesis, Biological Properties, and Molecular Modeling Investigations of Novel Tacrine Derivatives with a Combination of Acetylcholinesterase Inhibition and Cannabinoid CB1 Receptor Antagonism

N′-(Arylsulfonyl)pyrazoline-1-carboxamidines as Novel, Neutral 5-Hydroxytryptamine 6 Receptor (5-HT6R) Antagonists with Unique Structural Features

Synthesis and SAR of 1,4,5,6-tetrahydropyridazines as potent cannabinoid CB1 receptor antagonists

Two distinct classes of novel pyrazolinecarboxamides as potent cannabinoid CB1 receptor agonists

Synthesis and SAR of novel imidazoles as potent and selective cannabinoid CB2 receptor antagonists with high binding efficiencies

Probing the cannabinoid CB1/CB2 receptor subtype selectivity limits of 1,2-diarylimidazole-4-carboxamides by fine-tuning their 5-substitution pattern

The selective 5-HT6 receptor antagonist SLV has putative cognitive- and social interaction enhancing properties in rodent models of cognitive impairment

Spatially resolved generation profiles for onshore and offshore wind turbines: A case study of four Dutch energy transition scenarios

Development and application of an LC–MS/MS method for measuring the effect of (partial) agonists on cAMP accumulation in vitro

Optimization of N′-(arylsulfonyl)pyrazoline-1-carboxamidines by exploiting a novel interaction site in the 5-HT6 antagonistic binding pocket

The Association of Shelter Veterinarians veterinary medical care guidelines for spay-neuter programs

Synthesis, SAR and intramolecular hydrogen bonding pattern of 1,3,5-trisubstituted 4,5-dihydropyrazoles as potent cannabinoid CB1 receptor antagonists

Spatially resolved generation profiles for building, land and water-bound PV: a case study of four Dutch energy transition scenarios

Numerical Simulation and P arameter Optimization of the Inside In take and Outside Pressing Particle Collector

Lectotypification and Description of Clematis orientalis L. (Ranunculaceae)

Design, Synthesis, Biological Properties, and Molecular Modeling Investigations of Novel Tacrine Derivatives with a Combination of Acetylcholinesterase Inhibition and Cannabinoid CB 1 Receptor Antagonism

Optimization of N'-(arylsulfonyl)pyrazoline-1-carboxamidines by exploiting a novel interaction site in the 5-HT sub(6) antagonistic binding pocket

Characterization of cytoplasmic male sterility in Petunia hybrida and Zea mays. Localization and activity of cytochrome c oxidase

Synthesis and SAR of 1,4,5,6-tetrahydropyridazines as potent cannabinoid CB sub(1) receptor antagonists

Probing the cannabinoid CB sub(1)/CB sub(2) receptor subtype selectivity limits of 1,2-diarylimidazole-4-carboxamides by fine-tuning their 5-substitution pattern

Synthesis, SAR and intramolecular hydrogen bonding pattern of 1,3,5-trisubstituted 4,5-dihydropyrazoles as potent cannabinoid CB sub(1) receptor antagonists

Synthesis and SAR of novel imidazoles as potent and selective cannabinoid CB sub(2) receptor antagonists with high binding efficiencies

The sensitivity of thin-walled compression members to column axis imperfection

Synthesis, SAR and intramolecular hydrogen bonding pattern of 1,3,5-trisubstituted 4,5-dihydropyrazoles as potent cannabinoid CB(1) receptor antagonists

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