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Phase III dose selection of marzeptacog alfa (activated) informed by population pharmacokinetic modeling: A novel hemostatic drug

CPT: pharmacometrics and systems pharmacology, 2022-12, Vol.11 (12), p.1628-1637

2022

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Model‐informed pediatric dose selection of marzeptacog alfa (activated): An exposure matching strategy

CPT: pharmacometrics and systems pharmacology, 2023-07, Vol.12 (7), p.977-987

2023

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Phase 1/2 Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety, and Efficacy of Marzeptacog Alfa (activated) in the Treatment of Episodic Bleeding in Subjects with Inherited Bleeding Disorders

Blood, 2020-11, Vol.136 (Supplement 1), p.32-33

2020

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The Crimson 1 Study: A Phase 3 Study to Evaluate the Efficacy and Safety of Subcutaneous Marzeptocog Alfa (activated) for on-Demand Treatment and Control of Bleeding Episodes in Subjects with Hemophilia A or Hemophilia B, with Inhibitors

Blood, 2020-11, Vol.136 (Supplement 1), p.39-40

2020

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Fast Onset of Action of Subcutaneously Administered Marzeptacog Alfa (Activated) Supports on-Demand Treatment in Hemophilia a Mice

Blood, 2019-11, Vol.134 (Supplement_1), p.2420-2420

2019

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The Combination of Marzeptacog Alfa (Activated) or Eptacog Alfa (Activated) with Emicizumab Appears Comparable As Assessed By the Thrombin Generation Test in Hemophilia a Plasma

Blood, 2019-11, Vol.134 (Supplement_1), p.1112-1112

2019

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Efficacy and safety of pegzilarginase in arginase 1 deficiency (PEACE): a phase 3, randomized, double-blind, placebo-controlled, multi-centre trialResearch in context

EClinicalMedicine, 2024-02, Vol.68, p.102405

2024

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Efficacy and safety of pegzilarginase in arginase 1 deficiency (PEACE): a phase 3, randomized, double-blind, placebo-controlled, multi-centre trial

EClinicalMedicine, 2024-02, Vol.68, p.102405-102405, Article 102405

2024

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Abstract 1207: SNS-062 demonstrates efficacy in chronic lymphocytic leukemia in vitro and inhibits C481S mutated Bruton tyrosine kinase

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.1207-1207

2017

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First-in-Human Phase 1a Study of the Safety, Pharmacokinetics, and Pharmacodynamics of the Noncovalent Bruton Tyrosine Kinase (BTK) Inhibitor SNS-062 in Healthy Subjects

Blood, 2016-12, Vol.128 (22), p.2032-2032

2016

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Updated Results from a Multicenter, Open-Label, Dose-Escalation Phase 1b/2 Study of Single-Agent Oprozomib in Patients with Waldenström Macroglobulinemia (WM)

Blood, 2014-12, Vol.124 (21), p.1715-1715

2014

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Clinical Profile Of Single-Agent Modified-Release Oprozomib Tablets In Patients (Pts) With Hematologic Malignancies: Updated Results From a Multicenter, Open-Label, Dose Escalation Phase 1b/2 Study

Blood, 2013-11, Vol.122 (21), p.3184-3184

2013

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Oprozomib and Dexamethasone in Patients with Relapsed and/or Refractory Multiple Myeloma: Initial Results from the Dose Escalation Portion of a Phase 1b/2, Multicenter, Open-Label Study

Blood, 2014-12, Vol.124 (21), p.3453-3453

2014

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Clinical Profile of Single-Agent Oprozomib in Patients (Pts) with Multiple Myeloma (MM): Updated Results from a Multicenter, Open-Label, Dose Escalation Phase 1b/2 Study

Blood, 2014-12, Vol.124 (21), p.34-34

2014

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Breaking the Silence

Agenda (Durban), 1995-01, Vol.25 (25), p.92-93

Neuman, Linda

1995

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BREAKING THE SILENCE

Agenda (Durban), 1995-01, Vol.11 (25), p.92-93

Neuman, Linda

1995

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Pionery raketnoy tekhniki: Gansvindt, Goddard, Esno-P el’tri, Obert, Goman—Izbranniye trudiy (1891–1938) [Pioneers of rocket technology: Ganswindt, Goddard, Esnault-Pelterie, Oberth, and Hohmann—selected works (1891-1938)] ed. by T. M. Mell’kumov, V. N. Sokol’skiy (review)

Technology and culture, 1981, Vol.22 (1), p.202-203

1981

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Taking Science to the Moon: Lunar Experiments and the Apollo Program

Technology and Culture, 2002, Vol.43 (4), p.827-828

Ezell, Linda

2002

Volltextzugriff (PDF)

Pionery raketnoy tekhniki: Gansvindt, Goddard, Esno-Pel'tri, Obert, Goman-Izbranniye trudiy (1891-1938) (Pioneers of Rocket Technology: Ganswindt, Goddard, Esnault-Pelterie, Oberth, and Hohmann-Selected Works (1891-1938))

Technology and Culture, 1981, Vol.22 (1), p.202-203

1981

Volltextzugriff (PDF)

Moonport: A History of Apollo Launch Facilities and Operations

The Journal of American History, 1979, Vol.66 (3), p.713-714

Crouch, Thomas W.

1979

Volltextzugriff (PDF)

T. M. Mell'kumov and V. N. Sokol'skiy, eds., Pionery raketnoy tekhniki: Gansvindt, Goddard, Esno-Pel'tri, Obert, Goman - Izbranniye trudiy (1891-1938)" [Pioneers of rocket technology: Ganswindt, Goddard, Esnault-Pelterie, Oberth, and Hohmann - selected works (1891-1938)] (Book Review)

Technology and Culture, 1981, Vol.22 (1), p.202

1981

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The Impact of Professional Development and Coaching on Early Language and Literacy Instructional Practices

American educational research journal, 2009-06, Vol.46 (2), p.532-566

2009

Volltextzugriff (PDF)

Regional versus General Anesthesia for Promoting Independence after Hip Fracture (REGAIN): protocol for a pragmatic, international multicentre trial

BMJ open, 2016-11, Vol.6 (11), p.e013473-e013473

2016

Volltextzugriff (PDF)

Costs of distributing HIV self-testing kits in Eswatini through community and workplace models

BMC infectious diseases, 2024-02, Vol.22 (Suppl 1), p.976-976, Article 976

2024

Volltextzugriff (PDF)

Partner-delivered HIV self-test kits with and without financial incentives in antenatal care and index patients with HIV in Malawi: a three-arm, cluster-randomised controlled trial

The Lancet global health, 2021-07, Vol.9 (7), p.e977-e988

2021

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Phase III dose selection of marzeptacog alfa (activated) informed by population pharmacokinetic modeling: A novel hemostatic drug

Model‐informed pediatric dose selection of marzeptacog alfa (activated): An exposure matching strategy

Phase 1/2 Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety, and Efficacy of Marzeptacog Alfa (activated) in the Treatment of Episodic Bleeding in Subjects with Inherited Bleeding Disorders

The Crimson 1 Study: A Phase 3 Study to Evaluate the Efficacy and Safety of Subcutaneous Marzeptocog Alfa (activated) for on-Demand Treatment and Control of Bleeding Episodes in Subjects with Hemophilia A or Hemophilia B, with Inhibitors

Fast Onset of Action of Subcutaneously Administered Marzeptacog Alfa (Activated) Supports on-Demand Treatment in Hemophilia a Mice

The Combination of Marzeptacog Alfa (Activated) or Eptacog Alfa (Activated) with Emicizumab Appears Comparable As Assessed By the Thrombin Generation Test in Hemophilia a Plasma

Efficacy and safety of pegzilarginase in arginase 1 deficiency (PEACE): a phase 3, randomized, double-blind, placebo-controlled, multi-centre trialResearch in context

Efficacy and safety of pegzilarginase in arginase 1 deficiency (PEACE): a phase 3, randomized, double-blind, placebo-controlled, multi-centre trial

Abstract 1207: SNS-062 demonstrates efficacy in chronic lymphocytic leukemia in vitro and inhibits C481S mutated Bruton tyrosine kinase

First-in-Human Phase 1a Study of the Safety, Pharmacokinetics, and Pharmacodynamics of the Noncovalent Bruton Tyrosine Kinase (BTK) Inhibitor SNS-062 in Healthy Subjects

Updated Results from a Multicenter, Open-Label, Dose-Escalation Phase 1b/2 Study of Single-Agent Oprozomib in Patients with Waldenström Macroglobulinemia (WM)

Clinical Profile Of Single-Agent Modified-Release Oprozomib Tablets In Patients (Pts) With Hematologic Malignancies: Updated Results From a Multicenter, Open-Label, Dose Escalation Phase 1b/2 Study

Oprozomib and Dexamethasone in Patients with Relapsed and/or Refractory Multiple Myeloma: Initial Results from the Dose Escalation Portion of a Phase 1b/2, Multicenter, Open-Label Study

Clinical Profile of Single-Agent Oprozomib in Patients (Pts) with Multiple Myeloma (MM): Updated Results from a Multicenter, Open-Label, Dose Escalation Phase 1b/2 Study

Breaking the Silence

BREAKING THE SILENCE

Pionery raketnoy tekhniki: Gansvindt, Goddard, Esno-P el’tri, Obert, Goman—Izbranniye trudiy (1891–1938) [Pioneers of rocket technology: Ganswindt, Goddard, Esnault-Pelterie, Oberth, and Hohmann—selected works (1891-1938)] ed. by T. M. Mell’kumov, V. N. Sokol’skiy (review)

Taking Science to the Moon: Lunar Experiments and the Apollo Program

Pionery raketnoy tekhniki: Gansvindt, Goddard, Esno-Pel'tri, Obert, Goman-Izbranniye trudiy (1891-1938) (Pioneers of Rocket Technology: Ganswindt, Goddard, Esnault-Pelterie, Oberth, and Hohmann-Selected Works (1891-1938))

Moonport: A History of Apollo Launch Facilities and Operations

T. M. Mell'kumov and V. N. Sokol'skiy, eds., Pionery raketnoy tekhniki: Gansvindt, Goddard, Esno-Pel'tri, Obert, Goman - Izbranniye trudiy (1891-1938)" [Pioneers of rocket technology: Ganswindt, Goddard, Esnault-Pelterie, Oberth, and Hohmann - selected works (1891-1938)] (Book Review)

The Impact of Professional Development and Coaching on Early Language and Literacy Instructional Practices

Regional versus General Anesthesia for Promoting Independence after Hip Fracture (REGAIN): protocol for a pragmatic, international multicentre trial

Costs of distributing HIV self-testing kits in Eswatini through community and workplace models

Partner-delivered HIV self-test kits with and without financial incentives in antenatal care and index patients with HIV in Malawi: a three-arm, cluster-randomised controlled trial

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