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A Mechanistic Framework for In Vitro–In Vivo Extrapolation of Liver Membrane Transporters: Prediction of Drug–Drug Interaction Between Rosuvastatin and Cyclosporine

Clinical pharmacokinetics, 2014-01, Vol.53 (1), p.73-87

2014

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Interplay of metabolism and transport in determining oral drug absorption and gut wall metabolism: a simulation assessment using the "Advanced Dissolution, Absorption, Metabolism (ADAM)" model

Current drug metabolism, 2010-11, Vol.11 (9), p.716

2010

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Abundance of Hepatic Transporters in Caucasians: A Meta-Analysis

Drug metabolism and disposition, 2016-10, Vol.44 (10), p.1550-1561

2016

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Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug–drug interactions

European journal of pharmaceutical sciences, 2016-06, Vol.88, p.70-82

2016

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Absolute abundance and function of intestinal drug transporters: a prerequisite for fully mechanistic in vitro-in vivo extrapolation of oral drug absorption

Biopharmaceutics & drug disposition, 2013-01, Vol.34 (1), p.2-28

2013

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In Vitro-In Vivo Extrapolation Scaling Factors for Intestinal P-Glycoprotein and Breast Cancer Resistance Protein: Part I: A Cross-Laboratory Comparison of Transporter-Protein Abundances and Relative Expression Factors in Human Intestine and Caco-2 Cells

Drug metabolism and disposition, 2016-03, Vol.44 (3), p.297-307

2016

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In Vitro-In Vivo Extrapolation Scaling Factors for Intestinal P-glycoprotein and Breast Cancer Resistance Protein: Part II. The Impact of Cross-Laboratory Variations of Intestinal Transporter Relative Expression Factors on Predicted Drug Disposition

Drug metabolism and disposition, 2016-03, Vol.44 (3), p.476-480

2016

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Application of a Physiologically Based Pharmacokinetic Model to Predict OATP1B1‐Related Variability in Pharmacodynamics of Rosuvastatin

CPT: pharmacometrics and systems pharmacology, 2014-07, Vol.3 (7), p.1-9

2014

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Characterization of Contributing Factors to Variability in Morphine Clearance Through PBPK Modeling Implemented With OCT1 Transporter

CPT: pharmacometrics and systems pharmacology, 2017-02, Vol.6 (2), p.110-119

2017

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Initiation of Clement Surface Conditions on the Earliest Earth

Proceedings of the National Academy of Sciences - PNAS, 2001-03, Vol.98 (7), p.3666-3672

2001

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Low-temperature hydrothermal metamorphic mineralization of island-arc volcanics, South Apuseni Mountains, Romania

Clays and clay minerals, 2012-02, Vol.60 (1), p.1-17

2012

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Impact of extracellular protein binding on passive and active drug transport across caco-2 cells

Pharmaceutical research, 2006-02, Vol.23 (2), p.350-359

2006

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Mechanisms and geochemical significance of Si–Al substitution in zeolite solid solutions

Chemical geology, 2006-01, Vol.225 (3), p.373-387

2006

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Conduit enlargement in an eogenetic karst aquifer

Journal of hydrology (Amsterdam), 2010-11, Vol.393 (3), p.143-155

2010

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Enhanced resolution and quantitation from `ultrahigh' field NMR spectroscopy of glasses

Journal of non-crystalline solids, 2001-11, Vol.293, p.440-445

2001

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Spastic paresis after perinatal brain damage in rats is reduced by human cord blood mononuclear cells

Pediatric research, 2006-02, Vol.59 (2), p.244-249

2006

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New Approach Methodologies for Human-Relevant Biokinetics Predictions: Meeting the Paradigm Shift in Toxicology Towards an Animal-Free Chemical Risk Assessment

ALTEX, alternatives to animal experimentation, 2020-01, Vol.37 (4), p.607

2020

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Advantages and disadvantages of using bovine serum albumin and/or Cremophor EL as extracellular additives during transport studies of lipophilic compounds across Caco-2 monolayers

Journal of drug delivery science and technology, 2007, Vol.17 (4), p.259-266

2007

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pH-dependent bidirectional transport of weakly basic drugs across Caco-2 monolayers: Implications for drug-drug interactions

Pharmaceutical research, 2003-08, Vol.20 (8), p.1141-1148

2003

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Isothermal measurement of heats of hydration in zeolites by simultaneous thermogravimetry and differential scanning calorimetry

Clays and clay minerals, 2007-06, Vol.55 (3), p.239-252

2007

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Zeolite Parageneses in the North Atlantic Igneous Province: Implications for Geotectonics and Groundwater Quality of Basaltic Crust

International geology review, 2000-01, Vol.42 (1), p.15-44

2000

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pH-Dependent passive and active transport of acidic drugs across Caco-2 cell monolayers

European journal of pharmaceutical sciences, 2005-06, Vol.25 (2), p.211-220

2005

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A solid solution model for Si–Al substitution in disordered FAU and LTA zeolites

Microporous and mesoporous materials, 2001-11, Vol.49 (1), p.139-148

2001

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Affinities at the verapamil binding site of MDR1-encoded P-glycoprotein: drugs and analogs, stereoisomers and metabolites

International journal of clinical pharmacology and therapeutics, 2000-04, Vol.38 (4), p.168

2000

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Reproducibility of Brain Responses: High for Speech Perception, Low for Reading Difficulties

Scientific reports, 2019-06, Vol.9 (1), p.8487-8487, Article 8487

2019

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A Mechanistic Framework for In Vitro–In Vivo Extrapolation of Liver Membrane Transporters: Prediction of Drug–Drug Interaction Between Rosuvastatin and Cyclosporine

Interplay of metabolism and transport in determining oral drug absorption and gut wall metabolism: a simulation assessment using the "Advanced Dissolution, Absorption, Metabolism (ADAM)" model

Abundance of Hepatic Transporters in Caucasians: A Meta-Analysis

Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug–drug interactions

Absolute abundance and function of intestinal drug transporters: a prerequisite for fully mechanistic in vitro-in vivo extrapolation of oral drug absorption

In Vitro-In Vivo Extrapolation Scaling Factors for Intestinal P-Glycoprotein and Breast Cancer Resistance Protein: Part I: A Cross-Laboratory Comparison of Transporter-Protein Abundances and Relative Expression Factors in Human Intestine and Caco-2 Cells

In Vitro-In Vivo Extrapolation Scaling Factors for Intestinal P-glycoprotein and Breast Cancer Resistance Protein: Part II. The Impact of Cross-Laboratory Variations of Intestinal Transporter Relative Expression Factors on Predicted Drug Disposition

Application of a Physiologically Based Pharmacokinetic Model to Predict OATP1B1‐Related Variability in Pharmacodynamics of Rosuvastatin

Characterization of Contributing Factors to Variability in Morphine Clearance Through PBPK Modeling Implemented With OCT1 Transporter

Initiation of Clement Surface Conditions on the Earliest Earth

Low-temperature hydrothermal metamorphic mineralization of island-arc volcanics, South Apuseni Mountains, Romania

Impact of extracellular protein binding on passive and active drug transport across caco-2 cells

Mechanisms and geochemical significance of Si–Al substitution in zeolite solid solutions

Conduit enlargement in an eogenetic karst aquifer

Enhanced resolution and quantitation from `ultrahigh' field NMR spectroscopy of glasses

Spastic paresis after perinatal brain damage in rats is reduced by human cord blood mononuclear cells

New Approach Methodologies for Human-Relevant Biokinetics Predictions: Meeting the Paradigm Shift in Toxicology Towards an Animal-Free Chemical Risk Assessment

Advantages and disadvantages of using bovine serum albumin and/or Cremophor EL as extracellular additives during transport studies of lipophilic compounds across Caco-2 monolayers

pH-dependent bidirectional transport of weakly basic drugs across Caco-2 monolayers: Implications for drug-drug interactions

Isothermal measurement of heats of hydration in zeolites by simultaneous thermogravimetry and differential scanning calorimetry

Zeolite Parageneses in the North Atlantic Igneous Province: Implications for Geotectonics and Groundwater Quality of Basaltic Crust

pH-Dependent passive and active transport of acidic drugs across Caco-2 cell monolayers

A solid solution model for Si–Al substitution in disordered FAU and LTA zeolites

Affinities at the verapamil binding site of MDR1-encoded P-glycoprotein: drugs and analogs, stereoisomers and metabolites

Reproducibility of Brain Responses: High for Speech Perception, Low for Reading Difficulties

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