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First‐in‐human assessment of PRX002, an anti–α‐synuclein monoclonal antibody, in healthy volunteers

Movement disorders, 2017-02, Vol.32 (2), p.211-218

2017

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First-in-human assessment of PRX002, an anti-[alpha]-synuclein monoclonal antibody, in healthy volunteers

Movement disorders, 2017-02, Vol.32 (2), p.211

2017

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A rationale for determining, testing, and controlling specific impurities in pharmaceuticals that possess potential for genotoxicity

Regulatory toxicology and pharmacology, 2006-04, Vol.44 (3), p.198-211

2006

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Quantitative assessment of cumulative carcinogenic risk for multiple genotoxic impurities in a new drug substance

Regulatory toxicology and pharmacology, 2008-08, Vol.51 (3), p.270-277

2008

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Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposited forms of amyloid beta

The Journal of neuroscience, 2005-01, Vol.25 (3), p.629-636

2005

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Discovery of (R)‑4-Cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro‑1H‑pyrazolo[4,3‑c]quinoline (ELND006) and (R)‑4-Cyclopropyl-8-fluoro-5-(6-(trifluoromethyl)pyridin-3-ylsulfonyl)-4,5-dihydro‑2H‑pyrazolo[4,3‑c]quinoline (ELND007): Metabolically Stable γ‑Secretase Inhibitors that Selectively Inhibit the Production of Amyloid‑β over Notch

Journal of medicinal chemistry, 2013-07, Vol.56 (13), p.5261-5274

2013

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Analysis of Rodent Growth Data in Toxicology Studies

Toxicological sciences, 2002-04, Vol.66 (2), p.313-319

2002

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P1-017: Comparison of cisternal and lumbar cerebrospinal fluid amyloid-beta concentrations following oral administration of LY450139 dihydrate to Beagle dogs

Alzheimer's & dementia, 2008-07, Vol.4 (4), p.T210-T210

2008

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Effects of perinatal exposure to specific PCB congeners on thyroid hormone concentrations and thyroid histology in the rat

Toxicology letters, 1993-06, Vol.68 (3), p.311-323

1993

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First-in-human assessment of PRX002, an anti-α-synuclein monoclonal antibody, in healthy volunteers: Immunotherapy for Parkinson's Disease

Movement disorders, 2017-02, Vol.32 (2), p.211-218

2017

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Characterization of fumonisin toxicity in orally and intravenously dosed swine

Mycopathologia (1975), 1992-02, Vol.117 (1-2), p.83-96

1992

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Discovery of ( R )-4-Cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1 H -pyrazolo[4,3- c ]quinoline (ELND006) and ( R )-4-Cyclopropyl-8-fluoro-5-(6-(trifluoromethyl)pyridin-3-ylsulfonyl)-4,5-dihydro-2 H -pyrazolo[4,3- c ]quinoline (ELND007): Metabolically Stable γ-Secretase Inhibitors that Selectively Inhibit the Production of Amyloid-β over Notch

Journal of medicinal chemistry, 2013-07, Vol.56 (13), p.5261-5274

2013

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PCB congeners in the rat brain: Selective accumulation and lack of regionalization

Journal of toxicology and environmental health, 1994-12, Vol.43 (4), p.453-468

1994

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P2-053 Reduced β-amyloid burden, increased C-99 concentrations and evaluation of neuropathology in the brains of PDAPP mice given LY450139 dihydrate daily by gavage for 5 months

Neurobiology of aging, 2004-07, Vol.25, p.S238-S239

2004

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P4-358 In vitro and in vivo characterization of beta-amyloid antibodies binding to cerebral amyloid angiopathy (CAA) and the selective exacerbation of CAA-associated microhemorrhage

Neurobiology of aging, 2004-07, Vol.25, p.S577-S577

2004

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Temporal and dose-response features in swine fed corn screenings contaminated with fumonisin mycotoxins

Mycopathologia (1975), 1994-04, Vol.126 (1), p.27-40

1994

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Spatial Learning Deficits in Adult Rats Exposed to ortho-Substituted PCB Congeners during Gestation and Lactation

Fundamental and applied toxicology, 1995-06, Vol.26 (1), p.117-126

1995

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Exacerbation of Cerebral Amyloid Angiopathy-Associated Microhemorrhage in Amyloid Precursor Protein Transgenic Mice by Immunotherapy Is Dependent on Antibody Recognition of Deposited Forms of Amyloid {beta}

The Journal of neuroscience, 2005-01, Vol.25 (3), p.629

2005

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Effects of 3-Iodo-L-tyrosine, a Tyrosine Hydroxylase Inhibitor, on Eye Pigmentation and Biogenic Amines in the Planarian,Dugesia dorotocephala

Fundamental and applied toxicology, 1996-04, Vol.30 (2), p.153-161

1996

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The cumulative burden of surviving childhood cancer: an initial report from the St Jude Lifetime Cohort Study (SJLIFE)

The Lancet (British edition), 2017-12, Vol.390 (10112), p.2569-2582

2017

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Clinical ascertainment of health outcomes among adults treated for childhood cancer

JAMA : the journal of the American Medical Association, 2013-06, Vol.309 (22), p.2371

2013

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Screening Adult Survivors of Childhood Cancer for Cardiomyopathy: Comparison of Echocardiography and Cardiac Magnetic Resonance Imaging

Journal of clinical oncology, 2012-08, Vol.30 (23), p.2876-2884

2012

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Physiologic Frailty As a Sign of Accelerated Aging Among Adult Survivors of Childhood Cancer: A Report From the St Jude Lifetime Cohort Study

Journal of clinical oncology, 2013-12, Vol.31 (36), p.4496-4503

2013

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Comprehensive Echocardiographic Detection of Treatment-Related Cardiac Dysfunction in Adult Survivors of Childhood Cancer

Journal of the American College of Cardiology, 2015-06, Vol.65 (23), p.2511-2522

2015

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Exercise Intolerance, Mortality, and Organ System Impairment in Adult Survivors of Childhood Cancer

Journal of clinical oncology, 2020-01, Vol.38 (1), p.29-42

2020

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First‐in‐human assessment of PRX002, an anti–α‐synuclein monoclonal antibody, in healthy volunteers

First-in-human assessment of PRX002, an anti-[alpha]-synuclein monoclonal antibody, in healthy volunteers

A rationale for determining, testing, and controlling specific impurities in pharmaceuticals that possess potential for genotoxicity

Quantitative assessment of cumulative carcinogenic risk for multiple genotoxic impurities in a new drug substance

Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposited forms of amyloid beta

Analysis of Rodent Growth Data in Toxicology Studies

P1-017: Comparison of cisternal and lumbar cerebrospinal fluid amyloid-beta concentrations following oral administration of LY450139 dihydrate to Beagle dogs

Effects of perinatal exposure to specific PCB congeners on thyroid hormone concentrations and thyroid histology in the rat

First-in-human assessment of PRX002, an anti-α-synuclein monoclonal antibody, in healthy volunteers: Immunotherapy for Parkinson's Disease

Characterization of fumonisin toxicity in orally and intravenously dosed swine

PCB congeners in the rat brain: Selective accumulation and lack of regionalization

P2-053 Reduced β-amyloid burden, increased C-99 concentrations and evaluation of neuropathology in the brains of PDAPP mice given LY450139 dihydrate daily by gavage for 5 months

P4-358 In vitro and in vivo characterization of beta-amyloid antibodies binding to cerebral amyloid angiopathy (CAA) and the selective exacerbation of CAA-associated microhemorrhage

Temporal and dose-response features in swine fed corn screenings contaminated with fumonisin mycotoxins

Spatial Learning Deficits in Adult Rats Exposed to ortho-Substituted PCB Congeners during Gestation and Lactation

Exacerbation of Cerebral Amyloid Angiopathy-Associated Microhemorrhage in Amyloid Precursor Protein Transgenic Mice by Immunotherapy Is Dependent on Antibody Recognition of Deposited Forms of Amyloid {beta}

Effects of 3-Iodo-L-tyrosine, a Tyrosine Hydroxylase Inhibitor, on Eye Pigmentation and Biogenic Amines in the Planarian,Dugesia dorotocephala

The cumulative burden of surviving childhood cancer: an initial report from the St Jude Lifetime Cohort Study (SJLIFE)

Clinical ascertainment of health outcomes among adults treated for childhood cancer

Screening Adult Survivors of Childhood Cancer for Cardiomyopathy: Comparison of Echocardiography and Cardiac Magnetic Resonance Imaging

Physiologic Frailty As a Sign of Accelerated Aging Among Adult Survivors of Childhood Cancer: A Report From the St Jude Lifetime Cohort Study

Comprehensive Echocardiographic Detection of Treatment-Related Cardiac Dysfunction in Adult Survivors of Childhood Cancer

Exercise Intolerance, Mortality, and Organ System Impairment in Adult Survivors of Childhood Cancer

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