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CUX1, a haploinsufficient tumour suppressor gene overexpressed in advanced cancers

Nature reviews. Cancer, 2014-10, Vol.14 (10), p.673-682

2014

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CUX1 transcription factors: From biochemical activities and cell-based assays to mouse models and human diseases

Gene, 2012-04, Vol.497 (1), p.18-26

2012

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Role of the multifunctional CDP/Cut/Cux homeodomain transcription factor in regulating differentiation, cell growth and development

Gene, 2001-05, Vol.270 (1), p.1-15

Nepveu, Alain

2001

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CUT Domain Proteins in DNA Repair and Cancer

Cancers, 2021-06, Vol.13 (12), p.2953

2021

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Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven cellular senescence

Nature communications, 2016-12, Vol.7 (1), p.13719-13719, Article 13719

2016

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CUX2 Protein Functions as an Accessory Factor in the Repair of Oxidative DNA Damage

The Journal of biological chemistry, 2015-09, Vol.290 (37), p.22520-22531

2015

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CUX1 stimulates APE1 enzymatic activity and increases the resistance of glioblastoma cells to the mono-alkylating agent temozolomide

Neuro-oncology (Charlottesville, Va.), 2018-03, Vol.20 (4), p.484-493

2018

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RAS transformation requires CUX1-dependent repair of oxidative DNA damage

PLoS biology, 2014-03, Vol.12 (3), p.e1001807

2014

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CUX1 transcription factor is required for optimal ATM/ATR-mediated responses to DNA damage

Nucleic acids research, 2012-05, Vol.40 (10), p.4483-4495

2012

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Increased Expression and Activity of Nuclear Cathepsin L in Cancer Cells Suggests a Novel Mechanism of Cell Transformation

Molecular cancer research, 2007-09, Vol.5 (9), p.899-907

2007

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Apurinic/apyrimidinic endonuclease 1 performs multiple roles in controlling the outcome of cancer cells toward radiation and chemotherapeutic agents

Journal of Radiation and Cancer Research, 2018, Vol.9 (2), p.67-78

2018

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The function of CUX1 in oxidative DNA damage repair is needed to prevent premature senescence of mouse embryo fibroblasts

Oncotarget, 2015-02, Vol.6 (6), p.3613-3626

2015

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USP19 Deubiquitinating Enzyme Supports Cell Proliferation by Stabilizing KPC1, a Ubiquitin Ligase for p27Kip1

Molecular and Cellular Biology, 2009-01, Vol.29 (2), p.547-558

2009

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p110 CUX1 Homeodomain Protein Stimulates Cell Migration and Invasion in Part through a Regulatory Cascade Culminating in the Repression of E-cadherin and Occludin

The Journal of biological chemistry, 2009-10, Vol.284 (40), p.27701-27711

2009

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CUX1 and E2F1 Regulate Coordinated Expression of the Mitotic Complex Genes Ect2, MgcRacGAP, and MKLP1 in S Phase

Molecular and Cellular Biology, 2009, Vol.29 (2), p.570-581

2009

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Distinct clinical and biological implications of CUX1 in myeloid neoplasms

Blood advances, 2019-07, Vol.3 (14), p.2164-2178

2019

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Cut homeobox 1 causes chromosomal instability by promoting bipolar division after cytokinesis failure

Proceedings of the National Academy of Sciences - PNAS, 2011-02, Vol.108 (5), p.1949-1954

2011

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Mouse Mammary Tumor Virus p75 and p110 CUX1 Transgenic Mice Develop Mammary Tumors of Various Histologic Types

Cancer research (Chicago, Ill.), 2009-09, Vol.69 (18), p.7188-7197

2009

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p110 CUX1 Cooperates with E2F Transcription Factors in the Transcriptional Activation of Cell Cycle-Regulated Genes

Molecular and Cellular Biology, 2008-05, Vol.28 (10), p.3127-3138

2008

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Autocrine Activation of the Wnt/β-Catenin Pathway by CUX1 and GLIS1 in Breast Cancers

Biology open, 2014-10, Vol.3 (10), p.937-946

2014

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The BCL11A transcription factor stimulates the enzymatic activities of the OGG1 DNA glycosylase

Biological chemistry, 2024-09

2024

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Carboxyl-terminal Proteolytic Processing of CUX1 by a Caspase Enables Transcriptional Activation in Proliferating Cells

The Journal of biological chemistry, 2007-10, Vol.282 (41), p.30216-30226

2007

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The p110 Isoform of the CDP/Cux Transcription Factor Accelerates Entry into S Phase

Molecular and Cellular Biology, 2006-03, Vol.26 (6), p.2441-2455

2006

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Complete and Limited Proteolysis in Cell Cycle Progression

Cell cycle (Georgetown, Tex.), 2004-08, Vol.3 (8), p.984-987

2004

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The roles of CUX1 homeodomain proteins in the establishment of a transcriptional program required for cell migration and invasion

Cell adhesion & migration, 2010-07, Vol.4 (3), p.348-352

2010

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CUX1, a haploinsufficient tumour suppressor gene overexpressed in advanced cancers

CUX1 transcription factors: From biochemical activities and cell-based assays to mouse models and human diseases

Role of the multifunctional CDP/Cut/Cux homeodomain transcription factor in regulating differentiation, cell growth and development

CUT Domain Proteins in DNA Repair and Cancer

Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven cellular senescence

CUX2 Protein Functions as an Accessory Factor in the Repair of Oxidative DNA Damage

CUX1 stimulates APE1 enzymatic activity and increases the resistance of glioblastoma cells to the mono-alkylating agent temozolomide

RAS transformation requires CUX1-dependent repair of oxidative DNA damage

CUX1 transcription factor is required for optimal ATM/ATR-mediated responses to DNA damage

Increased Expression and Activity of Nuclear Cathepsin L in Cancer Cells Suggests a Novel Mechanism of Cell Transformation

Apurinic/apyrimidinic endonuclease 1 performs multiple roles in controlling the outcome of cancer cells toward radiation and chemotherapeutic agents

The function of CUX1 in oxidative DNA damage repair is needed to prevent premature senescence of mouse embryo fibroblasts

USP19 Deubiquitinating Enzyme Supports Cell Proliferation by Stabilizing KPC1, a Ubiquitin Ligase for p27Kip1

p110 CUX1 Homeodomain Protein Stimulates Cell Migration and Invasion in Part through a Regulatory Cascade Culminating in the Repression of E-cadherin and Occludin

CUX1 and E2F1 Regulate Coordinated Expression of the Mitotic Complex Genes Ect2, MgcRacGAP, and MKLP1 in S Phase

Distinct clinical and biological implications of CUX1 in myeloid neoplasms

Cut homeobox 1 causes chromosomal instability by promoting bipolar division after cytokinesis failure

Mouse Mammary Tumor Virus p75 and p110 CUX1 Transgenic Mice Develop Mammary Tumors of Various Histologic Types

p110 CUX1 Cooperates with E2F Transcription Factors in the Transcriptional Activation of Cell Cycle-Regulated Genes

Autocrine Activation of the Wnt/β-Catenin Pathway by CUX1 and GLIS1 in Breast Cancers

The BCL11A transcription factor stimulates the enzymatic activities of the OGG1 DNA glycosylase

Carboxyl-terminal Proteolytic Processing of CUX1 by a Caspase Enables Transcriptional Activation in Proliferating Cells

The p110 Isoform of the CDP/Cux Transcription Factor Accelerates Entry into S Phase

Complete and Limited Proteolysis in Cell Cycle Progression

The roles of CUX1 homeodomain proteins in the establishment of a transcriptional program required for cell migration and invasion

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