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Integrin-Targeting Strategies for Adenovirus Gene Therapy

Viruses, 2024-05, Vol.16 (5), p.770

Nemerow, Glen R

2024

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Structures and organization of adenovirus cement proteins provide insights into the role of capsid maturation in virus entry and infection

Proceedings of the National Academy of Sciences - PNAS, 2014-08, Vol.111 (32), p.11715-11720

2014

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Crystal Structure of Human Adenovirus at 3.5 Å Resolution

Science (American Association for the Advancement of Science), 2010-08, Vol.329 (5995), p.1071-1075

2010

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Adenovirus tales: from the cell surface to the nuclear pore complex

PLoS pathogens, 2015-06, Vol.11 (6), p.e1004821-e1004821

2015

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Adenovirus Protein VI Mediates Membrane Disruption following Capsid Disassembly

Journal of Virology, 2005-02, Vol.79 (4), p.1992-2000

2005

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Humoral immune response to adenovirus induce tolerogenic bystander dendritic cells that promote generation of regulatory T cells

PLoS pathogens, 2018-08, Vol.14 (8), p.e1007127-e1007127

2018

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Preferential Activation of Toll-Like Receptor Nine by CD46-Utilizing Adenoviruses

Journal of Virology, 2007-02, Vol.81 (3), p.1305-1312

2007

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Integrin and Defensin Modulate the Mechanical Properties of Adenovirus

Journal of Virology, 2013-03, Vol.87 (5), p.2756-2766

2013

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Identification of Adenovirus Serotype 5 Hexon Regions That Interact with Scavenger Receptors

Journal of Virology, 2012-02, Vol.86 (4), p.2293-2301

2012

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Insight into the mechanisms of adenovirus capsid disassembly from studies of defensin neutralization

PLoS pathogens, 2010-06, Vol.6 (6), p.e1000959

2010

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Functional Genetic and Biophysical Analyses of Membrane Disruption by Human Adenovirus

Journal of Virology, 2011-03, Vol.85 (6), p.2631-2641

2011

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Insights into Adenovirus Uncoating from Interactions with Integrins and Mediators of Host Immunity

Viruses, 2016-12, Vol.8 (12), p.337

2016

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Direct Evidence from Single-Cell Analysis that Human α-Defensins Block Adenovirus Uncoating To Neutralize Infection

Journal of Virology, 2010-04, Vol.84 (8), p.4041-4049

2010

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Coagulation factor defends adenovirus from immune attack

Nature medicine, 2013-04, Vol.19 (4), p.406-407

Nemerow, Glen R

2013

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An intrinsically disordered region of the adenovirus capsid is implicated in neutralization by human alpha defensin 5

PloS one, 2013-04, Vol.8 (4), p.e61571-e61571

2013

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Differential Regulation of Cell Motility and Invasion by FAK

The Journal of cell biology, 2003-03, Vol.160 (5), p.753-767

2003

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Reply to Campos: Revised structures of adenovirus cement proteins represent a consensus model for understanding virus assembly and disassembly

Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (43), p.E4544-E4545

2014

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Visualization of α-Helices in a 6-Ångstrom Resolution Cryoelectron Microscopy Structure of Adenovirus Allows Refinement of Capsid Protein Assignments

Journal of Virology, 2006-12, Vol.80 (24), p.12049-12059

2006

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Cryo-Electron Microscopy Structure of an Adenovirus-Integrin Complex Indicates Conformational Changes in both Penton Base and Integrin

Journal of Virology, 2009-11, Vol.83 (22), p.11491-11501

2009

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The Influence of Adenovirus Fiber Structure and Function on Vector Development for Gene Therapy

Molecular therapy, 2005-09, Vol.12 (3), p.384-393

2005

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β1 Integrin Mediates Internalization of Mammalian Reovirus

Journal of Virology, 2006-03, Vol.80 (6), p.2760-2770

2006

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Guiding plant virus particles to integrin-displaying cells

Nanoscale, 2012-01, Vol.4 (12), p.3698-3705

2012

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Membrane Cofactor Protein Is a Receptor for Adenoviruses Associated with Epidemic Keratoconjunctivitis

Journal of Virology, 2004-04, Vol.78 (8), p.3897-3905

2004

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Neutralizing Antibody Blocks Adenovirus Infection by Arresting Microtubule-Dependent Cytoplasmic Transport

Journal of Virology, 2008-07, Vol.82 (13), p.6492-6500

2008

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Cryo-Electron Microscopy Structure of Adenovirus Type 2 Temperature-Sensitive Mutant 1 Reveals Insight into the Cell Entry Defect

Journal of Virology, 2009-08, Vol.83 (15), p.7375-7383

2009

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Integrin-Targeting Strategies for Adenovirus Gene Therapy

Structures and organization of adenovirus cement proteins provide insights into the role of capsid maturation in virus entry and infection

Crystal Structure of Human Adenovirus at 3.5 Å Resolution

Adenovirus tales: from the cell surface to the nuclear pore complex

Adenovirus Protein VI Mediates Membrane Disruption following Capsid Disassembly

Humoral immune response to adenovirus induce tolerogenic bystander dendritic cells that promote generation of regulatory T cells

Preferential Activation of Toll-Like Receptor Nine by CD46-Utilizing Adenoviruses

Integrin and Defensin Modulate the Mechanical Properties of Adenovirus

Identification of Adenovirus Serotype 5 Hexon Regions That Interact with Scavenger Receptors

Insight into the mechanisms of adenovirus capsid disassembly from studies of defensin neutralization

Functional Genetic and Biophysical Analyses of Membrane Disruption by Human Adenovirus

Insights into Adenovirus Uncoating from Interactions with Integrins and Mediators of Host Immunity

Direct Evidence from Single-Cell Analysis that Human α-Defensins Block Adenovirus Uncoating To Neutralize Infection

Coagulation factor defends adenovirus from immune attack

An intrinsically disordered region of the adenovirus capsid is implicated in neutralization by human alpha defensin 5

Differential Regulation of Cell Motility and Invasion by FAK

Reply to Campos: Revised structures of adenovirus cement proteins represent a consensus model for understanding virus assembly and disassembly

Visualization of α-Helices in a 6-Ångstrom Resolution Cryoelectron Microscopy Structure of Adenovirus Allows Refinement of Capsid Protein Assignments

Cryo-Electron Microscopy Structure of an Adenovirus-Integrin Complex Indicates Conformational Changes in both Penton Base and Integrin

The Influence of Adenovirus Fiber Structure and Function on Vector Development for Gene Therapy

β1 Integrin Mediates Internalization of Mammalian Reovirus

Guiding plant virus particles to integrin-displaying cells

Membrane Cofactor Protein Is a Receptor for Adenoviruses Associated with Epidemic Keratoconjunctivitis

Neutralizing Antibody Blocks Adenovirus Infection by Arresting Microtubule-Dependent Cytoplasmic Transport

Cryo-Electron Microscopy Structure of Adenovirus Type 2 Temperature-Sensitive Mutant 1 Reveals Insight into the Cell Entry Defect

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