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Discovery of small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase

Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.1320-1326

2022

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Catalytic Mechanism of Bacteriophage T4 Rad50 ATP Hydrolysis

Biochemistry (Easton), 2014-09, Vol.53 (35), p.5647-5660

2014

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An Interaction between the Walker A and D-loop Motifs Is Critical to ATP Hydrolysis and Cooperativity in Bacteriophage T4 Rad50

The Journal of biological chemistry, 2011-07, Vol.286 (29), p.26258-26266

2011

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Ribonucleotide Misincorporation and Reverse Transcriptase Activities of Plasmodium falciparum Apicoplast DNA Polymerase

Biochemistry (Easton), 2022-12, Vol.61 (23), p.2742-2750

2022

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Functional evaluation of the C-terminal region of bacteriophage T4 Rad50

Biochemical and biophysical research communications, 2020-05, Vol.526 (2), p.485-490

2020

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Trypanosoma brucei Mitochondrial DNA Polymerase POLIB Contains a Novel Polymerase Domain Insertion That Confers Dominant Exonuclease Activity

Biochemistry (Easton), 2022-12, Vol.61 (23), p.2751-2765

2022

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The T4 Phage UvsW Protein Contains Both DNA Unwinding and Strand Annealing Activities

The Journal of biological chemistry, 2007-01, Vol.282 (1), p.407-416

2007

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Promising antimalarials targeting apicoplast DNA polymerase from Plasmodium falciparum

European journal of medicinal chemistry, 2022-12, Vol.243, p.114751-114751, Article 114751

2022

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Replication and maintenance of the Plasmodium falciparum apicoplast genome

Molecular and biochemical parasitology, 2016-08, Vol.208 (2), p.56-64

2016

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Autoinhibition of Bacteriophage T4 Mre11 by Its C-terminal Domain

The Journal of biological chemistry, 2014-09, Vol.289 (38), p.26505-26513

2014

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A network of allosterically coupled residues in the bacteriophage T4 Mre11–Rad50 complex

Protein science, 2016-11, Vol.25 (11), p.2054-2065

2016

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Kinetic Analysis of the Exonuclease Activity of the Bacteriophage T4 Mre11-Rad50 Complex

Methods in enzymology, 2018, Vol.600, p.135-156

2018

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Crystal Structure of the Apicoplast DNA Polymerase from Plasmodium falciparum: The First Look at a Plastidic A-Family DNA Polymerase

Journal of molecular biology, 2016-10, Vol.428 (20), p.3920-3934

2016

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Biochemical Characterization of Bacteriophage T4 Mre11-Rad50 Complex

The Journal of biological chemistry, 2011-01, Vol.286 (4), p.2382-2392

2011

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Fidelity, Mismatch Extension, and Proofreading Activity of the Plasmodium falciparum Apicoplast DNA Polymerase

Biochemistry (Easton), 2013-11, Vol.52 (44), p.7723-7730

2013

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Site-directed Mutations of T4 Helicase Loading Protein (gp59) Reveal Multiple Modes of DNA Polymerase Inhibition and the Mechanism of Unlocking by gp41 Helicase

The Journal of biological chemistry, 2006-03, Vol.281 (13), p.8697-8706

2006

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Functional Analysis of the Bacteriophage T4 Rad50 Homolog (gp46) Coiled-coil Domain

The Journal of biological chemistry, 2015-09, Vol.290 (39), p.23905-23915

2015

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A clamp-like biohybrid catalyst for DNA oxidation

Nature chemistry, 2013-11, Vol.5 (11), p.945

2013

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Response of the Bacteriophage T4 Replisome to Noncoding Lesions and Regression of a Stalled Replication Fork

Journal of molecular biology, 2010-09, Vol.401 (5), p.743-756

2010

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Interaction of T4 UvsW Helicase and Single-Stranded DNA Binding Protein gp32 through Its Carboxy-Terminal Acidic Tail

Journal of molecular biology, 2013-08, Vol.425 (16), p.2823-2839

2013

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Disruption of the Bacteriophage T4 Mre11 Dimer Interface Reveals a Two-state Mechanism for Exonuclease Activity

The Journal of biological chemistry, 2012-09, Vol.287 (37), p.31371-31381

2012

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Functional Evaluation of Bacteriophage T4 Rad50 Signature Motif Residues

Biochemistry (Easton), 2011-07, Vol.50 (27), p.6030-6040

2011

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RNA Primer Handoff in Bacteriophage T4 DNA Replication: THE ROLE OF SINGLE-STRANDED DNA-BINDING PROTEIN AND POLYMERASE ACCESSORY PROTEINS

The Journal of biological chemistry, 2008-08, Vol.283 (33), p.22838-22846

2008

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Coordination and processing of DNA ends during double-strand break repair: the role of the bacteriophage T4 Mre11/Rad50 (MR) complex

Genetics (Austin), 2013-11, Vol.195 (3), p.739-755

2013

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Inhibition of Fructose-1,6-bisphosphatase by a New Class of Allosteric Effectors

The Journal of biological chemistry, 2003-12, Vol.278 (51), p.51176-51183

2003

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Discovery of small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase

Catalytic Mechanism of Bacteriophage T4 Rad50 ATP Hydrolysis

An Interaction between the Walker A and D-loop Motifs Is Critical to ATP Hydrolysis and Cooperativity in Bacteriophage T4 Rad50

Ribonucleotide Misincorporation and Reverse Transcriptase Activities of Plasmodium falciparum Apicoplast DNA Polymerase

Functional evaluation of the C-terminal region of bacteriophage T4 Rad50

Trypanosoma brucei Mitochondrial DNA Polymerase POLIB Contains a Novel Polymerase Domain Insertion That Confers Dominant Exonuclease Activity

The T4 Phage UvsW Protein Contains Both DNA Unwinding and Strand Annealing Activities

Promising antimalarials targeting apicoplast DNA polymerase from Plasmodium falciparum

Replication and maintenance of the Plasmodium falciparum apicoplast genome

Autoinhibition of Bacteriophage T4 Mre11 by Its C-terminal Domain

A network of allosterically coupled residues in the bacteriophage T4 Mre11–Rad50 complex

Kinetic Analysis of the Exonuclease Activity of the Bacteriophage T4 Mre11-Rad50 Complex

Crystal Structure of the Apicoplast DNA Polymerase from Plasmodium falciparum: The First Look at a Plastidic A-Family DNA Polymerase

Biochemical Characterization of Bacteriophage T4 Mre11-Rad50 Complex

Fidelity, Mismatch Extension, and Proofreading Activity of the Plasmodium falciparum Apicoplast DNA Polymerase

Site-directed Mutations of T4 Helicase Loading Protein (gp59) Reveal Multiple Modes of DNA Polymerase Inhibition and the Mechanism of Unlocking by gp41 Helicase

Functional Analysis of the Bacteriophage T4 Rad50 Homolog (gp46) Coiled-coil Domain

A clamp-like biohybrid catalyst for DNA oxidation

Response of the Bacteriophage T4 Replisome to Noncoding Lesions and Regression of a Stalled Replication Fork

Interaction of T4 UvsW Helicase and Single-Stranded DNA Binding Protein gp32 through Its Carboxy-Terminal Acidic Tail

Disruption of the Bacteriophage T4 Mre11 Dimer Interface Reveals a Two-state Mechanism for Exonuclease Activity

Functional Evaluation of Bacteriophage T4 Rad50 Signature Motif Residues

RNA Primer Handoff in Bacteriophage T4 DNA Replication: THE ROLE OF SINGLE-STRANDED DNA-BINDING PROTEIN AND POLYMERASE ACCESSORY PROTEINS

Coordination and processing of DNA ends during double-strand break repair: the role of the bacteriophage T4 Mre11/Rad50 (MR) complex

Inhibition of Fructose-1,6-bisphosphatase by a New Class of Allosteric Effectors

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