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Oxysterol-Binding Protein Is a Phosphatidylinositol 4-Kinase Effector Required for HCV Replication Membrane Integrity and Cholesterol Trafficking

Gastroenterology (New York, N.Y. 1943), 2014-05, Vol.146 (5), p.1373-1385.e11

2014

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Structural and Functional Analysis of the Human HDAC4 Catalytic Domain Reveals a Regulatory Structural Zinc-binding Domain

The Journal of biological chemistry, 2008-09, Vol.283 (39), p.26694-26704

2008

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Metabolism of phosphatidylinositol 4-kinase IIIα-dependent PI4P Is subverted by HCV and is targeted by a 4-anilino quinazoline with antiviral activity

PLoS pathogens, 2012-03, Vol.8 (3), p.e1002576

2012

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NS5A inhibitors unmask differences in functional replicase complex half-life between different hepatitis C virus strains

PLoS pathogens, 2017-06, Vol.13 (6), p.e1006343

2017

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The α Isoform of Protein Kinase CKI Is Responsible for Hepatitis C Virus NS5A Hyperphosphorylation

Journal of Virology, 2006-11, Vol.80 (22), p.11305-11312

2006

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Reduction of Hepatitis C Virus NS5A Hyperphosphorylation by Selective Inhibition of Cellular Kinases Activates Viral RNA Replication in Cell Culture

Journal of Virology, 2004-12, Vol.78 (23), p.13306-13314

2004

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Probing the elusive catalytic activity of vertebrate class IIa histone deacetylases

Bioorganic & medicinal chemistry, 2008-03, Vol.18 (6), p.1814-1819

2008

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Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture

Nature microbiology, 2016-12, Vol.2 (3), Article 16247

2016

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Subversion of Cell Signaling Pathways by Hepatitis C Virus Nonstructural 5A Protein via Interaction with Grb2 and P85 Phosphatidylinositol 3-Kinase

Journal of Virology, 2002-09, Vol.76 (18), p.9207-9217

2002

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Hyperphosphorylation of the Hepatitis C Virus NS5A Protein Requires an Active NS3 Protease, NS4A, NS4B, and NS5A Encoded on the Same Polyprotein

Journal of Virology, 1999-12, Vol.73 (12), p.9984-9991

1999

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NS5A, a Nonstructural Protein of Hepatitis C Virus, Binds Growth Factor Receptor-Bound Protein 2 Adaptor Protein in a Src Homology 3 Domain/Ligand-Dependent Manner and Perturbs Mitogenic Signaling

Proceedings of the National Academy of Sciences - PNAS, 1999-05, Vol.96 (10), p.5533-5538

1999

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High-Throughput Screening of the Yeast Kinome: Identification of Human Serine/Threonine Protein Kinases That Phosphorylate the Hepatitis C Virus NS5A Protein

Journal of Virology, 2004-04, Vol.78 (7), p.3502-3513

2004

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Human CD1c+ dendritic cells secrete high levels of IL-12 and potently prime cytotoxic T-cell responses

Blood, 2013-08, Vol.122 (6), p.932-942

2013

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Cloning and Expression of Human G/T Mismatch-specific Thymine-DNA Glycosylase

The Journal of biological chemistry, 1996-05, Vol.271 (22), p.12767-12774

1996

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Erratum: Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture

Nature microbiology, 2017-01, Vol.2 (3), Article 17012

2017

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NS5A phosphorylation and hyperphosphorylation

Methods in molecular biology (Clifton, N.J.), 2009, Vol.510, p.95

Neddermann, Petra

2009

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IL‐10 promotes homeostatic proliferation of human CD8+ memory T cells and, when produced by CD1c+ DCs, shapes naive CD8+ T‐cell priming

European journal of immunology, 2016-07, Vol.46 (7), p.1622-1632

2016

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Hepatitis C Virus NS5A Is a Direct Substrate of Casein Kinase I-α, a Cellular Kinase Identified by Inhibitor Affinity Chromatography Using Specific NS5A Hyperphosphorylation Inhibitors

The Journal of biological chemistry, 2007-02, Vol.282 (8), p.5536-5544

2007

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The crystal structure of the quorum sensing protein TraR bound to its autoinducer and target DNA

The EMBO journal, 2002-09, Vol.21 (17), p.4393-4401

2002

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IL-10 promotes homeostatic proliferation of human CD8 super(+) memory T cells and, when produced by CD1c super(+) DCs, shapes naive CD8 super(+) T-cell priming

European journal of immunology, 2016-07, Vol.46 (7), p.1622-1632

2016

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Hepatitis C virus-specific directly acting antiviral drugs

Current topics in microbiology and immunology, 2013, Vol.369, p.289

2013

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Synthesis and SAR of piperazinyl- N-phenylbenzamides as inhibitors of hepatitis C virus RNA replication in cell culture

Bioorganic & medicinal chemistry letters, 2009-03, Vol.19 (6), p.1779-1783

2009

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Ser2194 Is a Highly Conserved Major Phosphorylation Site of the Hepatitis C Virus Nonstructural Protein NS5A

Virology (New York, N.Y.), 2000-12, Vol.278 (2), p.501-513

2000

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The purification of a mismatch-specific thymine-DNA glycosylase from HeLa cells

The Journal of biological chemistry, 1993-10, Vol.268 (28), p.21218-21224

1993

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Metabolism of Phosphatidylinositol 4-Kinase III[alpha]-Dependent PI4P Is Subverted by HCV and Is Targeted by a 4-Anilino Quinazoline with Antiviral Activity

PLoS pathogens, 2012-03, Vol.8 (3)

2012

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Oxysterol-Binding Protein Is a Phosphatidylinositol 4-Kinase Effector Required for HCV Replication Membrane Integrity and Cholesterol Trafficking

Structural and Functional Analysis of the Human HDAC4 Catalytic Domain Reveals a Regulatory Structural Zinc-binding Domain

Metabolism of phosphatidylinositol 4-kinase IIIα-dependent PI4P Is subverted by HCV and is targeted by a 4-anilino quinazoline with antiviral activity

NS5A inhibitors unmask differences in functional replicase complex half-life between different hepatitis C virus strains

The α Isoform of Protein Kinase CKI Is Responsible for Hepatitis C Virus NS5A Hyperphosphorylation

Reduction of Hepatitis C Virus NS5A Hyperphosphorylation by Selective Inhibition of Cellular Kinases Activates Viral RNA Replication in Cell Culture

Probing the elusive catalytic activity of vertebrate class IIa histone deacetylases

Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture

Subversion of Cell Signaling Pathways by Hepatitis C Virus Nonstructural 5A Protein via Interaction with Grb2 and P85 Phosphatidylinositol 3-Kinase

Hyperphosphorylation of the Hepatitis C Virus NS5A Protein Requires an Active NS3 Protease, NS4A, NS4B, and NS5A Encoded on the Same Polyprotein

NS5A, a Nonstructural Protein of Hepatitis C Virus, Binds Growth Factor Receptor-Bound Protein 2 Adaptor Protein in a Src Homology 3 Domain/Ligand-Dependent Manner and Perturbs Mitogenic Signaling

High-Throughput Screening of the Yeast Kinome: Identification of Human Serine/Threonine Protein Kinases That Phosphorylate the Hepatitis C Virus NS5A Protein

Human CD1c+ dendritic cells secrete high levels of IL-12 and potently prime cytotoxic T-cell responses

Cloning and Expression of Human G/T Mismatch-specific Thymine-DNA Glycosylase

Erratum: Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture

NS5A phosphorylation and hyperphosphorylation

IL‐10 promotes homeostatic proliferation of human CD8+ memory T cells and, when produced by CD1c+ DCs, shapes naive CD8+ T‐cell priming

Hepatitis C Virus NS5A Is a Direct Substrate of Casein Kinase I-α, a Cellular Kinase Identified by Inhibitor Affinity Chromatography Using Specific NS5A Hyperphosphorylation Inhibitors

The crystal structure of the quorum sensing protein TraR bound to its autoinducer and target DNA

IL-10 promotes homeostatic proliferation of human CD8 super(+) memory T cells and, when produced by CD1c super(+) DCs, shapes naive CD8 super(+) T-cell priming

Hepatitis C virus-specific directly acting antiviral drugs

Synthesis and SAR of piperazinyl- N-phenylbenzamides as inhibitors of hepatitis C virus RNA replication in cell culture

Ser2194 Is a Highly Conserved Major Phosphorylation Site of the Hepatitis C Virus Nonstructural Protein NS5A

The purification of a mismatch-specific thymine-DNA glycosylase from HeLa cells

Metabolism of Phosphatidylinositol 4-Kinase III[alpha]-Dependent PI4P Is Subverted by HCV and Is Targeted by a 4-Anilino Quinazoline with Antiviral Activity

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