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Coupling mammalian cell surface display with somatic hypermutation for the discovery and maturation of human antibodies

Proceedings of the National Academy of Sciences - PNAS, 2011-12, Vol.108 (51), p.20455-20460

2011

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Margin segmentation and volcano-tectonic architecture along the volcanic margin off Argentina/Uruguay, South Atlantic

Marine geology, 2007-10, Vol.244 (1), p.46-67

2007

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RG-101 Demonstrates Favorable in Vitro Antiviral Activity and Cross Resistance Profile to Support Clinical Combination Studies in HCV Patients

Journal of hepatology, 2016, Vol.64 (2), p.S409-S409

2016

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Giant mounded drifts in the Argentine Continental Margin: Origins, and global implications for the history of thermohaline circulation

Marine and petroleum geology, 2010-08, Vol.27 (7), p.1508-1530

2010

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An integrated approach to extreme thermostabilization and affinity maturation of an antibody

Protein engineering, design and selection, 2013-02, Vol.26 (2), p.151-164

2013

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P0904 : RG-101, A novel GalNAc-conjugated inhibitor of microrna-122, demonstrates significant viral load reduction and reduces liver steatosis in human hepatocyte chimeric mice infected with genotype 1A or hard-to-treat genotype 3A Hepatitis C Virus (HCV)

Journal of hepatology, 2015-04, Vol.62, p.S683-S683

2015

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P1352 : Pharmacokinetics and pharmacology of RG-101, a novel GalNAc-conjugated oligonucleotide targeting microrna-122, in healthy volunteers

Journal of hepatology, 2015-04, Vol.62, p.S689-S689

2015

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P0907 : Pharmacokinetics, pharmacodynamics, and toxicity profile of RG-101, a novel GalNAc-conjugated hepatocyte-targetng inhibitor of microrna-122, in rodents and cynomolgus monkeys

Journal of hepatology, 2015-04, Vol.62, p.S684-S685

2015

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A Single Dose of Anti-MIR122 Oligonucleotide RG-101 Results in a less Activated Phenotype of NK Cells in Patients with Chronic Hepatitis C

Journal of hepatology, 2016, Vol.64 (2), p.S415-S416

2016

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Sequence Analysis for Resistance Monitoring following a Single Dose of RG-101, an Anti-MIR Targeting Microrna-122, in Chronic Hepatitis C Patients

Journal of hepatology, 2016, Vol.64 (2), p.S406-S406

2016

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LO7 : A single subcutaneous dose of 2mg/kg or 4mg/kg of RG-101, a GalNAc-conjugated oligonucleotide with antagonist activity against MIR-122, results in significant viral load reductions in chronic hepatitis C patients

Journal of hepatology, 2015-04, Vol.62, p.S261-S261

2015

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Mud volcanoes at the front of the Makran accretionary complex, Pakistan

Marine geology, 2001-01, Vol.172 (1), p.57-73

2001

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South Atlantic volcanic margins

Journal of the Geological Society, 1997-05, Vol.154 (3), p.465-470

1997

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The Argentine continental margin north of 48°S: sedimentary successions, volcanic activity during breakup

Marine and petroleum geology, 1999-02, Vol.16 (1), p.1-25

1999

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Mobilization of Hematopoietic Stem and Progenitor Cell Subpopulations From the Marrow to the Blood of Mice Following Cyclophosphamide and/or Granulocyte Colony-Stimulating Factor

Blood, 1993-04, Vol.81 (7), p.1960-1967

1993

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High b-values in the leaky segment of the Tjörnes Fracture Zone north of Iceland: are they evidence for shallow magmatic heat sources?

Journal of volcanology and geothermal research, 2003-11, Vol.128 (1), p.15-29

2003

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Characteristics of an active vent in the fore-arc basin of the Sunda Arc, Indonesia

Marine geology, 2002-05, Vol.184 (1), p.121-141

2002

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THU-239 - RG-101 Demonstrates Favorable in Vitro Antiviral Activity and Cross Resistance Profile to Support Clinical Combination Studies in HCV Patients

Journal of hepatology, 2016, Vol.64 (2), p.S409-S409

2016

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A Compilation of Geophysical Data from the Lazarev Sea and the Riiser-Larsen Sea, Antarctica

Marine geophysical researches, 2004-09, Vol.25 (3-4), p.233-245

2004

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Bone morphogenetic protein 9 is a potent synergistic factor for murine hemopoietic progenitor cell generation and colony formation in serum-free cultures

Leukemia, 1999-03, Vol.13 (3), p.428-437

1999

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The great Sumatra–Andaman earthquakes — Imaging the boundary between the ruptures of the great 2004 and 2005 earthquakes

Earth and planetary science letters, 2008-05, Vol.269 (1), p.118-130

2008

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A8.9Neutralisation of miR-155 ameliorates collagen-induced arthritis

Annals of the rheumatic diseases, 2015-03, Vol.74 (Suppl 1), p.A84-A85

2015

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A8.9 Neutralisation of miR-155 ameliorates collagen-induced arthritis

Annals of the rheumatic diseases, 2015-03, Vol.74 (Suppl 1), p.A84-A85

2015

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Hematopoietic stem cell deficit of transplanted bone marrow previously exposed to cytotoxic agents

Experimental hematology, 1993, Vol.21 (1), p.156-162

1993

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Deep structure of the Namibia continental margin as derived from integrated geophysical studies

Journal of Geophysical Research, 2000-11, Vol.105 (B11), p.25829-25853

2000

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Coupling mammalian cell surface display with somatic hypermutation for the discovery and maturation of human antibodies

Margin segmentation and volcano-tectonic architecture along the volcanic margin off Argentina/Uruguay, South Atlantic

RG-101 Demonstrates Favorable in Vitro Antiviral Activity and Cross Resistance Profile to Support Clinical Combination Studies in HCV Patients

Giant mounded drifts in the Argentine Continental Margin: Origins, and global implications for the history of thermohaline circulation

An integrated approach to extreme thermostabilization and affinity maturation of an antibody

P0904 : RG-101, A novel GalNAc-conjugated inhibitor of microrna-122, demonstrates significant viral load reduction and reduces liver steatosis in human hepatocyte chimeric mice infected with genotype 1A or hard-to-treat genotype 3A Hepatitis C Virus (HCV)

P1352 : Pharmacokinetics and pharmacology of RG-101, a novel GalNAc-conjugated oligonucleotide targeting microrna-122, in healthy volunteers

P0907 : Pharmacokinetics, pharmacodynamics, and toxicity profile of RG-101, a novel GalNAc-conjugated hepatocyte-targetng inhibitor of microrna-122, in rodents and cynomolgus monkeys

A Single Dose of Anti-MIR122 Oligonucleotide RG-101 Results in a less Activated Phenotype of NK Cells in Patients with Chronic Hepatitis C

Sequence Analysis for Resistance Monitoring following a Single Dose of RG-101, an Anti-MIR Targeting Microrna-122, in Chronic Hepatitis C Patients

LO7 : A single subcutaneous dose of 2mg/kg or 4mg/kg of RG-101, a GalNAc-conjugated oligonucleotide with antagonist activity against MIR-122, results in significant viral load reductions in chronic hepatitis C patients

Mud volcanoes at the front of the Makran accretionary complex, Pakistan

South Atlantic volcanic margins

The Argentine continental margin north of 48°S: sedimentary successions, volcanic activity during breakup

Mobilization of Hematopoietic Stem and Progenitor Cell Subpopulations From the Marrow to the Blood of Mice Following Cyclophosphamide and/or Granulocyte Colony-Stimulating Factor

High b-values in the leaky segment of the Tjörnes Fracture Zone north of Iceland: are they evidence for shallow magmatic heat sources?

Characteristics of an active vent in the fore-arc basin of the Sunda Arc, Indonesia

THU-239 - RG-101 Demonstrates Favorable in Vitro Antiviral Activity and Cross Resistance Profile to Support Clinical Combination Studies in HCV Patients

A Compilation of Geophysical Data from the Lazarev Sea and the Riiser-Larsen Sea, Antarctica

Bone morphogenetic protein 9 is a potent synergistic factor for murine hemopoietic progenitor cell generation and colony formation in serum-free cultures

The great Sumatra–Andaman earthquakes — Imaging the boundary between the ruptures of the great 2004 and 2005 earthquakes

A8.9Neutralisation of miR-155 ameliorates collagen-induced arthritis

A8.9 Neutralisation of miR-155 ameliorates collagen-induced arthritis

Hematopoietic stem cell deficit of transplanted bone marrow previously exposed to cytotoxic agents

Deep structure of the Namibia continental margin as derived from integrated geophysical studies

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