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The Epileptic Heart: Concept and clinical evidence

Epilepsy & behavior, 2020-04, Vol.105, p.106946-106946, Article 106946

2020

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Epileptic heart: A clinical syndromic approach

Epilepsia (Copenhagen), 2021-08, Vol.62 (8), p.1780-1789

2021

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Spectrum of clinical applications of interlead ECG heterogeneity assessment: From myocardial ischemia detection to sudden cardiac death risk stratification

Annals of noninvasive electrocardiology, 2021-11, Vol.26 (6), p.e12894-n/a

2021

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Multifactorial Benefits of Chronic Vagus Nerve Stimulation on Autonomic Function and Cardiac Electrical Stability in Heart Failure Patients With Reduced Ejection Fraction

Frontiers in physiology, 2022-03, Vol.13, p.855756-855756

2022

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Continuous multi‐day tracking of post‐myocardial infarction recovery of cardiac electrical stability and autonomic tone using electrocardiogram patch monitors

Annals of noninvasive electrocardiology, 2023-01, Vol.28 (1), p.e13035-n/a

2023

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Autonomic regulation therapy suppresses quantitative T-wave alternans and improves baroreflex sensitivity in patients with heart failure enrolled in the ANTHEM-HF study

Heart rhythm, 2016-03, Vol.13 (3), p.721-728

2016

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If inhibition in the atrioventricular node by ivabradine causes rate-dependent slowing of conduction and reduces ventricular rate during atrial fibrillation

Heart rhythm, 2014-12, Vol.11 (12), p.2288-2296

2014

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Basis for sudden cardiac death prediction by T-wave alternans from an integrative physiology perspective

Heart rhythm, 2009-03, Vol.6 (3), p.416-422

2009

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Prediction of sudden cardiac death with automated high-throughput analysis of heterogeneity in standard resting 12-lead electrocardiograms

Heart rhythm, 2016-03, Vol.13 (3), p.713-720

2016

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Unmasking atrial repolarization to assess alternans, spatiotemporal heterogeneity, and susceptibility to atrial fibrillation

Heart rhythm, 2016-04, Vol.13 (4), p.953-961

2016

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Eleclazine, an inhibitor of the cardiac late sodium current, is superior to flecainide in suppressing catecholamine-induced ventricular tachycardia and T-wave alternans in an intact porcine model

Heart rhythm, 2017-03, Vol.14 (3), p.448-454

2017

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Inhibition of the cardiac late sodium current with eleclazine protects against ischemia-induced vulnerability to atrial fibrillation and reduces atrial and ventricular repolarization abnormalities in the absence and presence of concurrent adrenergic stimulation

Heart rhythm, 2016-09, Vol.13 (9), p.1860-1867

2016

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Eleclazine, a new selective cardiac late sodium current inhibitor, confers concurrent protection against autonomically induced atrial premature beats, repolarization alternans and heterogeneity, and atrial fibrillation in an intact porcine model

Heart rhythm, 2016-08, Vol.13 (8), p.1679-1686

2016

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The Selective Cardiac Late Sodium Current Inhibitor GS-458967 Suppresses Autonomically Triggered Atrial Fibrillation in an Intact Porcine Model

Journal of cardiovascular electrophysiology, 2015-12, Vol.26 (12), p.1364-1369

2015

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HCN2/SkM1 Gene Transfer Into Canine Left Bundle Branch Induces Stable, Autonomically Responsive Biological Pacing at Physiological Heart Rates

Journal of the American College of Cardiology, 2013-03, Vol.61 (11), p.1192-1201

2013

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Ranolazine Exerts Potent Effects on Atrial Electrical Properties and Abbreviates Atrial Fibrillation Duration in the Intact Porcine Heart

Journal of cardiovascular electrophysiology, 2009-07, Vol.20 (7), p.796-802

2009

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Selective late sodium current blockade with GS-458967 markedly reduces ischemia-induced atrial and ventricular repolarization alternans and ECG heterogeneity

Heart rhythm, 2014-10, Vol.11 (10), p.1827-1835

2014

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Quantitative Evaluation of Heartbeat Interval Time Series using Poincaré Analysis Reveals Distinct Patterns of Heart Rate Dynamics During Cycles of Vagus Nerve Stimulation in Patients with Heart Failure

Journal of electrocardiology, 2017-11, Vol.50 (6), p.898-903

2017

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T‐wave heterogeneity in standard resting 12‐lead ECGs is associated with 90‐day cardiac mortality in women following emergency department admission: A nested case–control study

Annals of noninvasive electrocardiology, 2021-05, Vol.26 (3), p.e12826-n/a

2021

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Selective late INa inhibition by GS-458967 exerts parallel suppression of catecholamine-induced hemodynamically significant ventricular tachycardia and T-wave alternans in an intact porcine model

Heart rhythm, 2015-12, Vol.12 (12), p.2508-2514

2015

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Low doses of ranolazine and dronedarone in combination exert potent protection against atrial fibrillation and vulnerability to ventricular arrhythmias during acute myocardial ischemia

Heart rhythm, 2013, Vol.10 (1), p.121-127

2013

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Antifibrillatory effect of ranolazine during severe coronary stenosis in the intact porcine model

Heart rhythm, 2011-04, Vol.8 (4), p.608-614

2011

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Effects of Exercise Rehabilitation on Cardiac Electrical Instability Assessed by T-Wave Alternans During Ambulatory Electrocardiogram Monitoring in Coronary Artery Disease Patients Without and With Diabetes Mellitus

The American journal of cardiology, 2014-09, Vol.114 (6), p.832-837

2014

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Relation of T-Wave Alternans to Mortality and Nonsustained Ventricular Tachycardia in Patients With Non–ST-Segment Elevation Acute Coronary Syndrome from the MERLIN-TIMI 36 Trial of Ranolazine Versus Placebo

The American journal of cardiology, 2014-07, Vol.114 (1), p.17-23

2014

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Speckle tracking strain and ECG heterogeneity correlate in transcatheter aortic valve replacement-induced left bundle branch blocks and right ventricular paced rhythms

Open heart, 2021-10, Vol.8 (2), p.e001542

2021

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The Epileptic Heart: Concept and clinical evidence

Epileptic heart: A clinical syndromic approach

Spectrum of clinical applications of interlead ECG heterogeneity assessment: From myocardial ischemia detection to sudden cardiac death risk stratification

Multifactorial Benefits of Chronic Vagus Nerve Stimulation on Autonomic Function and Cardiac Electrical Stability in Heart Failure Patients With Reduced Ejection Fraction

Continuous multi‐day tracking of post‐myocardial infarction recovery of cardiac electrical stability and autonomic tone using electrocardiogram patch monitors

Autonomic regulation therapy suppresses quantitative T-wave alternans and improves baroreflex sensitivity in patients with heart failure enrolled in the ANTHEM-HF study

If inhibition in the atrioventricular node by ivabradine causes rate-dependent slowing of conduction and reduces ventricular rate during atrial fibrillation

Basis for sudden cardiac death prediction by T-wave alternans from an integrative physiology perspective

Prediction of sudden cardiac death with automated high-throughput analysis of heterogeneity in standard resting 12-lead electrocardiograms

Unmasking atrial repolarization to assess alternans, spatiotemporal heterogeneity, and susceptibility to atrial fibrillation

Eleclazine, an inhibitor of the cardiac late sodium current, is superior to flecainide in suppressing catecholamine-induced ventricular tachycardia and T-wave alternans in an intact porcine model

Inhibition of the cardiac late sodium current with eleclazine protects against ischemia-induced vulnerability to atrial fibrillation and reduces atrial and ventricular repolarization abnormalities in the absence and presence of concurrent adrenergic stimulation

Eleclazine, a new selective cardiac late sodium current inhibitor, confers concurrent protection against autonomically induced atrial premature beats, repolarization alternans and heterogeneity, and atrial fibrillation in an intact porcine model

The Selective Cardiac Late Sodium Current Inhibitor GS-458967 Suppresses Autonomically Triggered Atrial Fibrillation in an Intact Porcine Model

HCN2/SkM1 Gene Transfer Into Canine Left Bundle Branch Induces Stable, Autonomically Responsive Biological Pacing at Physiological Heart Rates

Ranolazine Exerts Potent Effects on Atrial Electrical Properties and Abbreviates Atrial Fibrillation Duration in the Intact Porcine Heart

Selective late sodium current blockade with GS-458967 markedly reduces ischemia-induced atrial and ventricular repolarization alternans and ECG heterogeneity

Quantitative Evaluation of Heartbeat Interval Time Series using Poincaré Analysis Reveals Distinct Patterns of Heart Rate Dynamics During Cycles of Vagus Nerve Stimulation in Patients with Heart Failure

T‐wave heterogeneity in standard resting 12‐lead ECGs is associated with 90‐day cardiac mortality in women following emergency department admission: A nested case–control study

Selective late INa inhibition by GS-458967 exerts parallel suppression of catecholamine-induced hemodynamically significant ventricular tachycardia and T-wave alternans in an intact porcine model

Low doses of ranolazine and dronedarone in combination exert potent protection against atrial fibrillation and vulnerability to ventricular arrhythmias during acute myocardial ischemia

Antifibrillatory effect of ranolazine during severe coronary stenosis in the intact porcine model

Effects of Exercise Rehabilitation on Cardiac Electrical Instability Assessed by T-Wave Alternans During Ambulatory Electrocardiogram Monitoring in Coronary Artery Disease Patients Without and With Diabetes Mellitus

Relation of T-Wave Alternans to Mortality and Nonsustained Ventricular Tachycardia in Patients With Non–ST-Segment Elevation Acute Coronary Syndrome from the MERLIN-TIMI 36 Trial of Ranolazine Versus Placebo

Speckle tracking strain and ECG heterogeneity correlate in transcatheter aortic valve replacement-induced left bundle branch blocks and right ventricular paced rhythms

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