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Differences in Transporters Rather than Drug Targets Are the Principal Determinants of the Different Innate Sensitivities of Trypanosoma congolense and Trypanozoon Subgenus Trypanosomes to Diamidines and Melaminophenyl Arsenicals
International journal of molecular sciences, 2022-03, Vol.23 (5), p.2844
2022
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Activity of Compounds from Temperate Propolis against Trypanosoma brucei and Leishmania mexicana
Molecules (Basel, Switzerland), 2021-06, Vol.26 (13), p.3912
2021
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Cloning and Characterization of Trypanosoma congolense and T. vivax Nucleoside Transporters Reveal the Potential of P1-Type Carriers for the Discovery of Broad-Spectrum Nucleoside-Based Therapeutics against Animal African Trypanosomiasis
International journal of molecular sciences, 2023-02, Vol.24 (4), p.3144
2023
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Nucleoside Transport and Nucleobase Uptake Null Mutants in Leishmania mexicana for the Routine Expression and Characterization of Purine and Pyrimidine Transporters
International journal of molecular sciences, 2022-08, Vol.23 (15), p.8139
2022
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A Toxoplasma gondii Oxopurine Transporter Binds Nucleobases and Nucleosides Using Different Binding Modes
International journal of molecular sciences, 2022-01, Vol.23 (2), p.710
2022
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The Activity of Red Nigerian Propolis and Some of Its Components against Trypanosoma brucei and Trypanosoma congolense
Molecules (Basel, Switzerland), 2023-01, Vol.28 (2), p.622
2023
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The Antiprotozoal Activity of Papua New Guinea Propolis and Its Triterpenes
Molecules (Basel, Switzerland), 2022-03, Vol.27 (5), p.1622
2022
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Investigation of 5'-Norcarbocyclic Nucleoside Analogues as Antiprotozoal and Antibacterial Agents
Molecules (Basel, Switzerland), 2019-09, Vol.24 (19), p.3433
2019
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Novel flavanones with anti-trypanosomal activity isolated from Zambian and Tanzanian propolis samples
International journal for parasitology -- drugs and drug resistance, 2020-12, Vol.14, p.201-207
2020
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Antiparasitic and Cytotoxic Activity of Bokkosin, A Novel Diterpene-Substituted Chromanyl Benzoquinone From Calliandra portoricensis
Frontiers in chemistry, 2020-11, Vol.8
2020
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Comprehensive characterization of purine and pyrimidine transport activities in Trichomonas vaginalis and functional cloning of a trichomonad nucleoside transporter
Molecular microbiology, 2021-12, Vol.116 (6), p.1489-1511
2021
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Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs
Journal of antimicrobial chemotherapy, 2014-03, Vol.69 (3), p.651-663
2014
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Deazapurine Nucleoside Analogues for the Treatment of Trichomonas vaginalis
ACS infectious diseases, 2021-06, Vol.7 (6), p.1752-1764
2021
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Protocols for the routine screening of drug sensitivity in the human parasite Trichomonas vaginalis
Methods in molecular biology (Clifton, N.J.), 2015, Vol.1263, p.103
2015
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Validation of novel fluorescence assays for the routine screening of drug susceptibilities of Trichomonas vaginalis
Journal of antimicrobial chemotherapy, 2012-04, Vol.67 (4), p.933-943
2012
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Cloning and Characterization of ITrypanosoma congolense/I and IT. vivax/I Nucleoside Transporters Reveal the Potential of P1-Type Carriers for the Discovery of Broad-Spectrum Nucleoside-Based Therapeutics against Animal African Trypanosomiasis
International journal of molecular sciences, 2023-02, Vol.24 (4)
2023
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Trypanosoma brucei: expression of multiple purine transporters prevents the development of allopurinol resistance
Experimental parasitology, 2005-02, Vol.109 (2), p.80-86
2005
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In and out of the minor groove: interaction of an AT-rich DNA with the drug CD27
Acta crystallographica. Section D, Biological crystallography., 2014-06, Vol.70 (6), p.1614-1621
2014
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