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Vitamin D and Its Receptor from a Structural Perspective

Nutrients, 2022-07, Vol.14 (14), p.2847

Rochel, Natacha

2022

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Cytosolic sequestration of the vitamin D receptor as a therapeutic option for vitamin D-induced hypercalcemia

Nature communications, 2020-12, Vol.11 (1), p.6249-11, Article 6249

2020

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Recurrent activating mutations of PPARγ associated with luminal bladder tumors

Nature communications, 2019-01, Vol.10 (1), p.253-253, Article 253

2019

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Quercetin potentializes the respective cytotoxic activity of gemcitabine or doxorubicin on 3D culture of AsPC-1 or HepG2 cells, through the inhibition of HIF-1α and MDR1

PloS one, 2020-10, Vol.15 (10), p.e0240676

2020

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Structural aspects of Vitamin D endocrinology

Molecular and cellular endocrinology, 2017-09, Vol.453, p.22-35

2017

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HR-Bac, a toolbox based on homologous recombination for expression, screening and production of multiprotein complexes using the baculovirus expression system

Scientific reports, 2022-02, Vol.12 (1), p.2030-2030, Article 2030

2022

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9-cis-13,14-Dihydroretinoic Acid Is an Endogenous Retinoid Acting as RXR Ligand in Mice

PLoS genetics, 2015-06, Vol.11 (6), p.e1005213-e1005213

2015

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Author Correction: HR-Bac, a toolbox based on homologous recombination for expression, screening and production of multiprotein complexes using the baculovirus expression system

Scientific reports, 2022-02, Vol.12 (1), p.3443-3443, Article 3443

2022

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Carborane-based design of a potent vitamin D receptor agonist

Chemical science (Cambridge), 2016-01, Vol.7 (2), p.1033-1037

2016

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1α,25(OH)2-3-epi-vitamin D3, a natural physiological metabolite of vitamin D3: its synthesis, biological activity and crystal structure with its receptor

PloS one, 2011-03, Vol.6 (3), p.e18124-e18124

2011

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Structural analysis of nuclear receptors: From isolated domains to integral proteins

Molecular and cellular endocrinology, 2012-01, Vol.348 (2), p.466-473

2012

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The Tumor Suppressor FBW7 and the Vitamin D Receptor Are Mutual Cofactors in Protein Turnover and Transcriptional Regulation

Molecular cancer research, 2019-03, Vol.17 (3), p.709-719

2019

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Aromatic-Based Design of Highly Active and Noncalcemic Vitamin D Receptor Agonists

Journal of medicinal chemistry, 2018-06, Vol.61 (11), p.4928-4937

2018

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Vitamin D Analogs Bearing C-20 Modifications Stabilize the Agonistic Conformation of Non-Responsive Vitamin D Receptor Variants

International journal of molecular sciences, 2022-07, Vol.23 (15), p.8445

2022

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4-Hydroxy-1α,25-Dihydroxyvitamin D3: Synthesis and Structure–Function Study

Biomolecules (Basel, Switzerland), 2024-05, Vol.14 (5), p.551

2024

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Design, synthesis and evaluation of side-chain hydroxylated derivatives of lithocholic acid as potent agonists of the vitamin D receptor (VDR)

Bioorganic chemistry, 2021-10, Vol.115, p.105202-105202, Article 105202

2021

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Structural Basis for the Accommodation of Bis- and Tris-Aromatic Derivatives in Vitamin D Nuclear Receptor

Journal of medicinal chemistry, 2012-10, Vol.55 (19), p.8440-8449

2012

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Lithocholic acid-based design of noncalcemic vitamin D receptor agonists

Bioorganic chemistry, 2021-06, Vol.111, p.104878, Article 104878

2021

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A Vitamin D Receptor Selectively Activated by Gemini Analogs Reveals Ligand Dependent and Independent Effects

Cell reports (Cambridge), 2015-02, Vol.10 (4), p.516-526

2015

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Structural basis of natural promoter recognition by the retinoid X nuclear receptor

Scientific reports, 2015-02, Vol.5 (1), p.8216-8216, Article 8216

2015

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Modulators of vitamin D nuclear receptor: recent advances from structural studies

Current topics in medicinal chemistry, 2014-01, Vol.14 (21), p.2368

2014

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Diastereotopic and Deuterium Effects in Gemini

Journal of medicinal chemistry, 2013-05, Vol.56 (10), p.3878-3888

2013

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Structure–function relationships in nuclear receptors: the facts

Trends in biochemical sciences (Amsterdam. Regular ed.), 2015-06, Vol.40 (6), p.287-290

2015

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Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor

Nature, 2003-11, Vol.426 (6962), p.91-96

2003

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The "Phantom Effect" of the Rexinoid LG100754: structural and functional insights

PloS one, 2010-11, Vol.5 (11), p.e15119-e15119

2010

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Vitamin D and Its Receptor from a Structural Perspective

Cytosolic sequestration of the vitamin D receptor as a therapeutic option for vitamin D-induced hypercalcemia

Recurrent activating mutations of PPARγ associated with luminal bladder tumors

Quercetin potentializes the respective cytotoxic activity of gemcitabine or doxorubicin on 3D culture of AsPC-1 or HepG2 cells, through the inhibition of HIF-1α and MDR1

Structural aspects of Vitamin D endocrinology

HR-Bac, a toolbox based on homologous recombination for expression, screening and production of multiprotein complexes using the baculovirus expression system

9-cis-13,14-Dihydroretinoic Acid Is an Endogenous Retinoid Acting as RXR Ligand in Mice

Author Correction: HR-Bac, a toolbox based on homologous recombination for expression, screening and production of multiprotein complexes using the baculovirus expression system

Carborane-based design of a potent vitamin D receptor agonist

1α,25(OH)2-3-epi-vitamin D3, a natural physiological metabolite of vitamin D3: its synthesis, biological activity and crystal structure with its receptor

Structural analysis of nuclear receptors: From isolated domains to integral proteins

The Tumor Suppressor FBW7 and the Vitamin D Receptor Are Mutual Cofactors in Protein Turnover and Transcriptional Regulation

Aromatic-Based Design of Highly Active and Noncalcemic Vitamin D Receptor Agonists

Vitamin D Analogs Bearing C-20 Modifications Stabilize the Agonistic Conformation of Non-Responsive Vitamin D Receptor Variants

4-Hydroxy-1α,25-Dihydroxyvitamin D3: Synthesis and Structure–Function Study

Design, synthesis and evaluation of side-chain hydroxylated derivatives of lithocholic acid as potent agonists of the vitamin D receptor (VDR)

Structural Basis for the Accommodation of Bis- and Tris-Aromatic Derivatives in Vitamin D Nuclear Receptor

Lithocholic acid-based design of noncalcemic vitamin D receptor agonists

A Vitamin D Receptor Selectively Activated by Gemini Analogs Reveals Ligand Dependent and Independent Effects

Structural basis of natural promoter recognition by the retinoid X nuclear receptor

Modulators of vitamin D nuclear receptor: recent advances from structural studies

Diastereotopic and Deuterium Effects in Gemini

Structure–function relationships in nuclear receptors: the facts

Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor

The "Phantom Effect" of the Rexinoid LG100754: structural and functional insights

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