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VPS4A Mutations in Humans Cause Syndromic Congenital Dyserythropoietic Anemia due to Cytokinesis and Trafficking Defects

American journal of human genetics, 2020-12, Vol.107 (6), p.1149-1156

2020

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IODVA1, a guanidinobenzimidazole derivative, targets Rac activity and Ras-driven cancer models

PloS one, 2020-03, Vol.15 (3), p.e0229801-e0229801

2020

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Real-time genomic profiling of histiocytoses identifies early-kinase domain BRAF alterations while improving treatment outcomes

JCI insight, 2017-02, Vol.2 (3), p.e89473-e89473

2017

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Inhibition of the RacGEF VAV3 by the small molecule IODVA1 impedes RAC signaling and overcomes resistance to tyrosine kinase inhibition in acute lymphoblastic leukemia

Leukemia, 2022-03, Vol.36 (3), p.637-647

2022

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GPC-100, a novel CXCR4 antagonist, improves in vivo hematopoietic cell mobilization when combined with propranolol

PloS one, 2023-10, Vol.18 (10), p.e0287863-e0287863

2023

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Sequential control of myeloid cell proliferation and differentiation by cytokine receptor-based chimeric antigen receptors

PloS one, 2022-12, Vol.17 (12), p.e0279409-e0279409

2022

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Molecular dynamics study on the strengthening behavior of Delta and Omicron SARS-CoV-2 spike RBD improved receptor-binding affinity

PloS one, 2022-11, Vol.17 (11), p.e0277745-e0277745

2022

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Abstract LB198: Inhibition of the RAC Activator VAV3 by the small molecule IODVA1 impedes RAC signaling & overcomes resistance to tyrosine kinase inhibition in lymphoblastic leukemia

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.LB198-LB198

2021

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UBASH3B/Sts-1-CBL axis regulates myeloid proliferation in human preleukemia induced by AML1-ETO

Leukemia, 2016-03, Vol.30 (3), p.728-739

2016

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IODVA1, a Guanidinobenzimidazole Derivative with in vivo Activity Against Ras-Driven Cancer Models

SSRN Electronic Journal

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Impact of Nanoconfinement on Polylactide Crystallization and Gas Barrier Properties

ACS applied materials & interfaces, 2020-02, Vol.12 (8), p.9953-9965

2020

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Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair

Oncogene, 2014-10, Vol.33 (40), p.4803-4812

2014

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Willis elastodynamic homogenization theory revisited for periodic media

Journal of the mechanics and physics of solids, 2015-04, Vol.77, p.158-178

2015

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On asymptotic elastodynamic homogenization approaches for periodic media

Journal of the mechanics and physics of solids, 2016-03, Vol.88, p.274-290

2016

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A generalized theory of elastodynamic homogenization for periodic media

International journal of solids and structures, 2016-05, Vol.84, p.139-146

2016

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A Phosphatase Activity of Sts-1 Contributes to the Suppression of TCR Signaling

Molecular cell, 2007-08, Vol.27 (3), p.486-497

2007

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Sts-2 Is a Phosphatase That Negatively Regulates Zeta-associated Protein (ZAP)-70 and T Cell Receptor Signaling Pathways

The Journal of biological chemistry, 2011-05, Vol.286 (18), p.15943-15954

2011

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Structure of the Dominant Negative S17N Mutant of Ras

Biochemistry (Easton), 2010-03, Vol.49 (9), p.1970-1974

2010

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Hypospadias Prevalence and Trends in International Birth Defect Surveillance Systems, 1980–2010

European urology, 2019-10, Vol.76 (4), p.482-490

2019

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The Structural Basis for the Transition from Ras-GTP to Ras-GDP

Proceedings of the National Academy of Sciences - PNAS, 2002-09, Vol.99 (19), p.12138-12142

2002

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The Small Molecule IODVA1 Inhibits the Rac Guanine Nucleotide Exchange Factor Vav3 and Overcomes TKI-Resistance in Ph+(BCR-ABL1) B-ALL

Blood, 2019-11, Vol.134 (Supplement_1), p.4647-4647

2019

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Structure of the Rho Family GTP-Binding Protein Cdc42 in Complex with the Multifunctional Regulator RhoGDI

Cell, 2000-02, Vol.100 (3), p.345-356

2000

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Structure of the G60A Mutant of Ras

The Journal of biological chemistry, 2005-07, Vol.280 (27), p.25697-25705

2005

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The Sts proteins target tyrosine phosphorylated, ubiquitinated proteins within TCR signaling pathways

Molecular immunology, 2009-10, Vol.46 (16), p.3224-3231

2009

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The 2.2 angstrom crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

Nature (London), 1995-06, Vol.375 (6532), p.554-560

1995

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VPS4A Mutations in Humans Cause Syndromic Congenital Dyserythropoietic Anemia due to Cytokinesis and Trafficking Defects

IODVA1, a guanidinobenzimidazole derivative, targets Rac activity and Ras-driven cancer models

Real-time genomic profiling of histiocytoses identifies early-kinase domain BRAF alterations while improving treatment outcomes

Inhibition of the RacGEF VAV3 by the small molecule IODVA1 impedes RAC signaling and overcomes resistance to tyrosine kinase inhibition in acute lymphoblastic leukemia

GPC-100, a novel CXCR4 antagonist, improves in vivo hematopoietic cell mobilization when combined with propranolol

Sequential control of myeloid cell proliferation and differentiation by cytokine receptor-based chimeric antigen receptors

Molecular dynamics study on the strengthening behavior of Delta and Omicron SARS-CoV-2 spike RBD improved receptor-binding affinity

Abstract LB198: Inhibition of the RAC Activator VAV3 by the small molecule IODVA1 impedes RAC signaling & overcomes resistance to tyrosine kinase inhibition in lymphoblastic leukemia

UBASH3B/Sts-1-CBL axis regulates myeloid proliferation in human preleukemia induced by AML1-ETO

IODVA1, a Guanidinobenzimidazole Derivative with in vivo Activity Against Ras-Driven Cancer Models

Impact of Nanoconfinement on Polylactide Crystallization and Gas Barrier Properties

Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair

Willis elastodynamic homogenization theory revisited for periodic media

On asymptotic elastodynamic homogenization approaches for periodic media

A generalized theory of elastodynamic homogenization for periodic media

A Phosphatase Activity of Sts-1 Contributes to the Suppression of TCR Signaling

Sts-2 Is a Phosphatase That Negatively Regulates Zeta-associated Protein (ZAP)-70 and T Cell Receptor Signaling Pathways

Structure of the Dominant Negative S17N Mutant of Ras

Hypospadias Prevalence and Trends in International Birth Defect Surveillance Systems, 1980–2010

The Structural Basis for the Transition from Ras-GTP to Ras-GDP

The Small Molecule IODVA1 Inhibits the Rac Guanine Nucleotide Exchange Factor Vav3 and Overcomes TKI-Resistance in Ph+(BCR-ABL1) B-ALL

Structure of the Rho Family GTP-Binding Protein Cdc42 in Complex with the Multifunctional Regulator RhoGDI

Structure of the G60A Mutant of Ras

The Sts proteins target tyrosine phosphorylated, ubiquitinated proteins within TCR signaling pathways

The 2.2 angstrom crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

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