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Drug Metabolism Handbook: Concepts and Applications in Cancer Research

2, 2022

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UPLC–MS for metabolomics: a giant step forward in support of pharmaceutical research

Drug discovery today, 2017-02, Vol.22 (2), p.463-470

2017

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A Burned-Out CD8 + T-cell Subset Expands in the Tumor Microenvironment and Curbs Cancer Immunotherapy

Cancer discovery, 2021-07, Vol.11 (7), p.1700-1715

2021

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Dilysine-Methylene Diphenyl Diisocyanate (MDI), a Urine Biomarker of MDI Exposure?

Chemical research in toxicology, 2019-04, Vol.32 (4), p.557-565

2019

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Automation of sample preparation for mass cytometry barcoding in support of clinical research: protocol optimization

Analytical and bioanalytical chemistry, 2017-03, Vol.409 (9), p.2363-2372

2017

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Impact of recent innovations in the use of mass cytometry in support of drug development

Drug discovery today, 2015-10, Vol.20 (10), p.1169-1175

2015

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In vitro cleavage of diisocyanate-glutathione conjugates by human gamma-glutamyl transpeptidase-1

Xenobiotica, 2016-08, Vol.46 (8), p.726-732

2016

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Polymerization of hexamethylene diisocyanate in solution and a 260.23 m/z [M+H]+ ion in exposed human cells

Analytical biochemistry, 2018-02, Vol.543, p.21-29

2018

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Metabolic disposition of the anti-cancer agent [14C]laromustine in male rats

Xenobiotica, 2015-08, Vol.45 (8), p.711-721

2015

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Mass cytometry moving forward in support of clinical research: advantages and considerations

Bioanalysis, 2016-02, Vol.8 (4), p.255-257

2016

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Rapid label-free profiling of oral cancer biomarker proteins using nano-UPLC-Q-TOF ion mobility mass spectrometry

Proteomics. Clinical applications, 2016-03, Vol.10 (3), p.280-289

2016

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Population pharmacokinetic (PK) analysis of laromustine, an emerging alkylating agent, in cancer patients

Xenobiotica, 2017-05, Vol.47 (5), p.394-407

2017

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Progress in automation of mass cytometry barcoding for drug development

Bioanalysis, 2016-07, Vol.8 (14), p.1429-1435

2016

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Development and Validation of LC-MS-MS Assay for the Determination of the Emerging Alkylating Agent Laromustine and Its Active Metabolite in Human Plasma

Journal of chromatographic science, 2019-03, Vol.57 (3), p.195-203

2019

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Reaction products of hexamethylene diisocyanate vapors with "self" molecules in the airways of rabbits exposed via tracheostomy

Xenobiotica, 2018-05, Vol.48 (5), p.488-497

2018

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Biotransformation and Metabolite Elucidation of Xenobiotics: Characterization and Identification

Nassar, Ala F

1. Aufl., 2010

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Di-Lysine-Methylene Diphenyl Diisocyanate (MDI), a Urine Biomarker of MDI Exposure?

Chemical research in toxicology, 2019-02, Vol.32 (4), p.557-565

2019

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Accelerating Metabolite Identification Mass Spectrometry Technology Drives Metabolite Identification Studies Forward

Drug Metabolism Handbook, 2022, p.267-302

2022

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Role of Structural Modifications of Drug Candidates to Enhance Metabolic Stability

Drug Metabolism Handbook, 2022, p.303-322

2022

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Chemical Structural Alert and Reactive Metabolite Concept as Applied in Medicinal Chemistry to Minimize the Toxicity of Drug Candidates

Drug Metabolism Handbook, 2022, p.345-372

2022

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Drug Design Strategies: Role of Structural Modifications of Drug Candidates to Improve PK Parameters of New Drugs

Drug Metabolism Handbook, 2022, p.323-343

2022

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CyTOF supports efficient detection of immune cell subsets from small samples

Journal of immunological methods, 2014-12, Vol.415, p.1-5

2014

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Targeting the CSF1/CSF1R axis is a potential treatment strategy for malignant meningiomas

Neuro-oncology (Charlottesville, Va.), 2021-11, Vol.23 (11), p.1922-1935

2021

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Abstract 1635: Multiplexed analysis of fixed tumor tissues using imaging mass cytometry

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.1635-1635

2017

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Case Study: Metabolism and Reactions of Alkylating Agents in Cancer Therapy

Drug Metabolism Handbook, 2022, p.893-922

2022

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Drug Metabolism Handbook: Concepts and Applications in Cancer Research

UPLC–MS for metabolomics: a giant step forward in support of pharmaceutical research

A Burned-Out CD8 + T-cell Subset Expands in the Tumor Microenvironment and Curbs Cancer Immunotherapy

Dilysine-Methylene Diphenyl Diisocyanate (MDI), a Urine Biomarker of MDI Exposure?

Automation of sample preparation for mass cytometry barcoding in support of clinical research: protocol optimization

Impact of recent innovations in the use of mass cytometry in support of drug development

In vitro cleavage of diisocyanate-glutathione conjugates by human gamma-glutamyl transpeptidase-1

Polymerization of hexamethylene diisocyanate in solution and a 260.23 m/z [M+H]+ ion in exposed human cells

Metabolic disposition of the anti-cancer agent [14C]laromustine in male rats

Mass cytometry moving forward in support of clinical research: advantages and considerations

Rapid label-free profiling of oral cancer biomarker proteins using nano-UPLC-Q-TOF ion mobility mass spectrometry

Population pharmacokinetic (PK) analysis of laromustine, an emerging alkylating agent, in cancer patients

Progress in automation of mass cytometry barcoding for drug development

Development and Validation of LC-MS-MS Assay for the Determination of the Emerging Alkylating Agent Laromustine and Its Active Metabolite in Human Plasma

Reaction products of hexamethylene diisocyanate vapors with "self" molecules in the airways of rabbits exposed via tracheostomy

Biotransformation and Metabolite Elucidation of Xenobiotics: Characterization and Identification

Di-Lysine-Methylene Diphenyl Diisocyanate (MDI), a Urine Biomarker of MDI Exposure?

Accelerating Metabolite Identification Mass Spectrometry Technology Drives Metabolite Identification Studies Forward

Role of Structural Modifications of Drug Candidates to Enhance Metabolic Stability

Chemical Structural Alert and Reactive Metabolite Concept as Applied in Medicinal Chemistry to Minimize the Toxicity of Drug Candidates

Drug Design Strategies: Role of Structural Modifications of Drug Candidates to Improve PK Parameters of New Drugs

CyTOF supports efficient detection of immune cell subsets from small samples

Targeting the CSF1/CSF1R axis is a potential treatment strategy for malignant meningiomas

Abstract 1635: Multiplexed analysis of fixed tumor tissues using imaging mass cytometry

Case Study: Metabolism and Reactions of Alkylating Agents in Cancer Therapy

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