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Transport function, regulation, and biology of human monocarboxylate transporter 1 (hMCT1) and 4 (hMCT4)

Pharmacology & therapeutics (Oxford), 2021-10, Vol.226, p.107862-107862, Article 107862

2021

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The rs35217482 (T755I) Single-Nucleotide Polymorphism in Aldehyde Oxidase-1 Attenuates Protein Dimer Formation and Reduces the Rates of Phthalazine Metabolism

Drug metabolism and disposition, 2022-09, Vol.50 (9), p.1126-1131

2022

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Pharmacological Inhibition of MCT4 Reduces 4-Hydroxytamoxifen Sensitivity by Increasing HIF-1α Protein Expression in ER-Positive MCF-7 Breast Cancer Cells

Biological and Pharmaceutical Bulletin, 2021/09/01, Vol.44(9), pp.1247-1253

2021

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Preexisting autoimmune disease is a risk factor for immune-related adverse events: a meta-analysis

Supportive care in cancer, 2021-12, Vol.29 (12), p.7747-7753

2021

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Molecular characterization of the orphan transporter SLC16A9, an extracellular pH- and Na+-sensitive creatine transporter

Biochemical and biophysical research communications, 2020-02, Vol.522 (2), p.539-544

2020

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Homology modeling and site-directed mutagenesis identify amino acid residues underlying the substrate selection mechanism of human monocarboxylate transporters 1 (hMCT1) and 4 (hMCT4)

Cellular and molecular life sciences : CMLS, 2019-12, Vol.76 (24), p.4905-4921

2019

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Different mechanisms of cisplatin resistance development in human lung cancer cells

Biochemical and biophysical research communications, 2020-10, Vol.530 (4), p.745-750

2020

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Identification of the essential extracellular aspartic acids conserved in human monocarboxylate transporters 1, 2, and 4

Biochemical and biophysical research communications, 2020-09, Vol.529 (4), p.1061-1065

2020

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Atorvastatin Exerts More Selective Inhibitory Effects on hMCT2 than on hMCT1 and hMCT4

Anticancer research, 2023-07, Vol.43 (7), p.3015

2023

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Anticancer effects of non-steroidal anti-inflammatory drugs against cancer cells and cancer stem cells

Toxicology in vitro, 2021-08, Vol.74, p.105155-105155, Article 105155

2021

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Antioxidant effect of ascorbic acid against cisplatin-induced nephrotoxicity and P-glycoprotein expression in rats

European journal of pharmacology, 2021-10, Vol.909, p.174395, Article 174395

2021

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Gamma-Aminobutyric Acid (GABA) Attenuates Ischemia Reperfusion-Induced Alterations in Intestinal Immunity

Biological and Pharmaceutical Bulletin, 2018/12/01, Vol.41(12), pp.1874-1878

2018

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Monocarboxylate transporter 4 involves in energy metabolism and drug sensitivity in hypoxia

Scientific reports, 2023-01, Vol.13 (1), p.1501-1501, Article 1501

2023

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Analysis of α-Defensin 5 Secretion in Differentiated Caco-2 Cells: Comparison of Cell Bank Origin

Biological and Pharmaceutical Bulletin, 2021/02/01, Vol.44(2), pp.275-278

2021

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Non-steroidal Anti-inflammatory Drugs Are a Risk Factor for Cisplatin-induced Nephrotoxicity: A Meta-analysis of Retrospective Studies

Anticancer research, 2020-03, Vol.40 (3), p.1747-1751

2020

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Mutual role of ecto-5'-nucleotidase/CD73 and concentrative nucleoside transporter 3 in the intestinal uptake of dAMP

PloS one, 2019-10, Vol.14 (10), p.e0223892-e0223892

2019

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Involvement of SLC16A1/MCT1 and SLC16A3/MCT4 in l‐lactate transport in the hepatocellular carcinoma cell line

Biopharmaceutics & drug disposition, 2022-10, Vol.43 (5), p.183-191

2022

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Monocarboxylate Transporters 1 and 2 Are Responsible for L-Lactate Uptake in Differentiated Human Neuroblastoma SH-SY5Y Cells

Biological and Pharmaceutical Bulletin, 2024/04/04, Vol.47(4), pp.764-770

2024

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Fructose suppresses uric acid excretion to the intestinal lumen as a result of the induction of oxidative stress by NADPH oxidase activation

Biochimica et biophysica acta. General subjects, 2017-03, Vol.1861 (3), p.559-566

2017

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Relationships between plasma lactate, plasma alanine, genetic variations in lactate transporters and type 2 diabetes in the Japanese population

Drug metabolism and pharmacokinetics, 2020-02, Vol.35 (1), p.131-138

2020

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Regorafenib Is Transported by the Organic Anion Transporter 1B1 and the Multidrug Resistance Protein 2

Biological and Pharmaceutical Bulletin, 2015/04/01, Vol.38(4), pp.582-586

2015

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Effects of single and repetitive valproic acid administration on the gene expression of placental transporters in pregnant rats: An analysis by gestational period

Reproductive toxicology (Elmsford, N.Y.), 2020-09, Vol.96, p.47-56

2020

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The flexible cytoplasmic loop 3 contributes to the substrate affinity of human monocarboxylate transporters

Biochimica et biophysica acta. Biomembranes, 2017-10, Vol.1859 (10), p.1790-1795

2017

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Analysis of the effects of polyunsaturated fatty acids on transporter expressions using a PCR array: Induction of xCT/SLC7A11 in human placental BeWo cells

Placenta (Eastbourne), 2019-01, Vol.75, p.34-41

2019

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Effect of diclofenac on SLC16A3/MCT4 by the Caco-2 cell line

Drug metabolism and pharmacokinetics, 2016-06, Vol.31 (3), p.218-223

2016

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Transport function, regulation, and biology of human monocarboxylate transporter 1 (hMCT1) and 4 (hMCT4)

The rs35217482 (T755I) Single-Nucleotide Polymorphism in Aldehyde Oxidase-1 Attenuates Protein Dimer Formation and Reduces the Rates of Phthalazine Metabolism

Pharmacological Inhibition of MCT4 Reduces 4-Hydroxytamoxifen Sensitivity by Increasing HIF-1α Protein Expression in ER-Positive MCF-7 Breast Cancer Cells

Preexisting autoimmune disease is a risk factor for immune-related adverse events: a meta-analysis

Molecular characterization of the orphan transporter SLC16A9, an extracellular pH- and Na+-sensitive creatine transporter

Homology modeling and site-directed mutagenesis identify amino acid residues underlying the substrate selection mechanism of human monocarboxylate transporters 1 (hMCT1) and 4 (hMCT4)

Different mechanisms of cisplatin resistance development in human lung cancer cells

Identification of the essential extracellular aspartic acids conserved in human monocarboxylate transporters 1, 2, and 4

Atorvastatin Exerts More Selective Inhibitory Effects on hMCT2 than on hMCT1 and hMCT4

Anticancer effects of non-steroidal anti-inflammatory drugs against cancer cells and cancer stem cells

Antioxidant effect of ascorbic acid against cisplatin-induced nephrotoxicity and P-glycoprotein expression in rats

Gamma-Aminobutyric Acid (GABA) Attenuates Ischemia Reperfusion-Induced Alterations in Intestinal Immunity

Monocarboxylate transporter 4 involves in energy metabolism and drug sensitivity in hypoxia

Analysis of α-Defensin 5 Secretion in Differentiated Caco-2 Cells: Comparison of Cell Bank Origin

Non-steroidal Anti-inflammatory Drugs Are a Risk Factor for Cisplatin-induced Nephrotoxicity: A Meta-analysis of Retrospective Studies

Mutual role of ecto-5'-nucleotidase/CD73 and concentrative nucleoside transporter 3 in the intestinal uptake of dAMP

Involvement of SLC16A1/MCT1 and SLC16A3/MCT4 in l‐lactate transport in the hepatocellular carcinoma cell line

Monocarboxylate Transporters 1 and 2 Are Responsible for L-Lactate Uptake in Differentiated Human Neuroblastoma SH-SY5Y Cells

Fructose suppresses uric acid excretion to the intestinal lumen as a result of the induction of oxidative stress by NADPH oxidase activation

Relationships between plasma lactate, plasma alanine, genetic variations in lactate transporters and type 2 diabetes in the Japanese population

Regorafenib Is Transported by the Organic Anion Transporter 1B1 and the Multidrug Resistance Protein 2

Effects of single and repetitive valproic acid administration on the gene expression of placental transporters in pregnant rats: An analysis by gestational period

The flexible cytoplasmic loop 3 contributes to the substrate affinity of human monocarboxylate transporters

Analysis of the effects of polyunsaturated fatty acids on transporter expressions using a PCR array: Induction of xCT/SLC7A11 in human placental BeWo cells

Effect of diclofenac on SLC16A3/MCT4 by the Caco-2 cell line

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