UB Paderborn / Katalog / Suche / in CDI

Characterization of the Hepatitis C Virus NS2/3 Processing Reaction by Using a Purified Precursor Protein

Journal of Virology, 2001-10, Vol.75 (20), p.9939-9946

2001

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Inhibitor binding induces active site stabilization of the HCV NS3 protein serine protease domain

The EMBO journal, 2000-03, Vol.19 (6), p.1195-1206

2000

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Interdomain Communication in Hepatitis C Virus Polymerase Abolished by Small Molecule Inhibitors Bound to a Novel Allosteric Site

The Journal of biological chemistry, 2005-08, Vol.280 (33), p.29765-29770

2005

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Preclinical pharmacokinetics and metabolism of a potent non-nucleoside inhibitor of the hepatitis C virus NS5B polymerase

Xenobiotica, 2005-10, Vol.35 (10-11), p.1035-1054

2005

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Mechanism of Action and Antiviral Activity of Benzimidazole-Based Allosteric Inhibitors of the Hepatitis C Virus RNA-Dependent RNA Polymerase

Journal of Virology, 2003-12, Vol.77 (24), p.13225-13231

2003

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Potent Inhibitors of Subgenomic Hepatitis C Virus RNA Replication through Optimization of Indole-N-Acetamide Allosteric Inhibitors of the Viral NS5B Polymerase

Journal of medicinal chemistry, 2005-07, Vol.48 (14), p.4547-4557

2005

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2-(2-Thienyl)-5,6-dihydroxy-4-carboxypyrimidines as Inhibitors of the Hepatitis C Virus NS5B Polymerase: Discovery, SAR, Modeling, and Mutagenesis

Journal of medicinal chemistry, 2006-03, Vol.49 (5), p.1693-1705

2006

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In Vitro Selection and Characterization of Hepatitis C Virus Serine Protease Variants Resistant to an Active-Site Peptide Inhibitor

Journal of Virology, 2003-03, Vol.77 (6), p.3669-3679

2003

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Development and Preliminary Optimization of Indole-N-Acetamide Inhibitors of Hepatitis C Virus NS5B Polymerase

Journal of medicinal chemistry, 2005-03, Vol.48 (5), p.1314-1317

2005

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Inhibition of the hepatitis C virus NS3/4A protease. The crystal structures of two protease-inhibitor complexes

The Journal of biological chemistry, 2000-03, Vol.275 (10), p.7152-7157

2000

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Binding of a Noncovalent Inhibitor Exploiting the S′ region Stabilizes the Hepatitis C virus NS3 Protease Conformation in the Absence of Cofactor

Journal of molecular biology, 2009-01, Vol.385 (4), p.1142-1155

2009

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Bacteriohopanetetrol from chemical degradation of an oil shale kerogen

Nature (London), 1987-03, Vol.326 (6109), p.179-181

1987

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Suzuki Coupling at the 2-Position of Densely Functionalized Pyrimidones

Synthesis (Stuttgart), 2006-04, Vol.2006 (8), p.1343-1350

2006

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Substrate Specificity of the Hepatitis C Virus Serine Protease NS3

The Journal of biological chemistry, 1997-04, Vol.272 (14), p.9204-9209

1997

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Evolution, synthesis and SAR of tripeptide α-ketoacid Inhibitors of the hepatitis C virus NS3/NS4A serine protease

Bioorganic & medicinal chemistry letters, 2002-02, Vol.12 (4), p.705-708

2002

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α-Ketoacids Are Potent Slow Binding Inhibitors of the Hepatitis C Virus NS3 Protease

Biochemistry (Easton), 2000-02, Vol.39 (7), p.1849-1861

2000

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A Continuous Assay of Hepatitis C Virus Protease Based on Resonance Energy Transfer Depsipeptide Substrates

Analytical biochemistry, 1996-08, Vol.240 (1), p.60-67

1996

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Enhancement of intestinal absorption of 2-methyl cytidine prodrugs

Drug delivery, 2010-05, Vol.17 (4), p.214-222

2010

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SAR and pharmacokinetic studies on phenethylamide inhibitors of the hepatitis C virus NS3/NS4A serine protease

Bioorganic & medicinal chemistry letters, 2004-09, Vol.14 (17), p.4575-4579

2004

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Synthesis of Ethynylcyclopropanes from Epoxides

Synthesis (Stuttgart), 1991, Vol.1991 (12), p.1168-1170

1991

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Hepatitis C virus protease inhibitors: current progress and future challenges

Current medicinal chemistry, 2001-07, Vol.8 (8), p.919

2001

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Application of intramolecular Heck reactions to the preparation of steroid and terpene intermediates having cis A-B ring fusions. Model studies for the total synthesis of complex cardenolides

Tetrahedron, 1994, Vol.50 (2), p.347-358

1994

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Probing the Active Site of the Hepatitis C Virus Serine Protease by Fluorescence Resonance Energy Transfer

The Journal of biological chemistry, 2000-05, Vol.275 (20), p.15106-15113

2000

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Synthesis of vinylcyclopropanes from epoxides

Journal of organic chemistry, 1991-01, Vol.56 (2), p.717-723

1991

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3-Methoxy-1-phenylthio-1-propene as d1 / d3 Synthon: Application for an Asymmetric Synthesis of (S)-(+)-Parasorbic Acid

Synlett, 1994-08, Vol.1994 (8), p.594-596

1994

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Characterization of the Hepatitis C Virus NS2/3 Processing Reaction by Using a Purified Precursor Protein

Inhibitor binding induces active site stabilization of the HCV NS3 protein serine protease domain

Interdomain Communication in Hepatitis C Virus Polymerase Abolished by Small Molecule Inhibitors Bound to a Novel Allosteric Site

Preclinical pharmacokinetics and metabolism of a potent non-nucleoside inhibitor of the hepatitis C virus NS5B polymerase

Mechanism of Action and Antiviral Activity of Benzimidazole-Based Allosteric Inhibitors of the Hepatitis C Virus RNA-Dependent RNA Polymerase

Potent Inhibitors of Subgenomic Hepatitis C Virus RNA Replication through Optimization of Indole-N-Acetamide Allosteric Inhibitors of the Viral NS5B Polymerase

2-(2-Thienyl)-5,6-dihydroxy-4-carboxypyrimidines as Inhibitors of the Hepatitis C Virus NS5B Polymerase: Discovery, SAR, Modeling, and Mutagenesis

In Vitro Selection and Characterization of Hepatitis C Virus Serine Protease Variants Resistant to an Active-Site Peptide Inhibitor

Development and Preliminary Optimization of Indole-N-Acetamide Inhibitors of Hepatitis C Virus NS5B Polymerase

Inhibition of the hepatitis C virus NS3/4A protease. The crystal structures of two protease-inhibitor complexes

Binding of a Noncovalent Inhibitor Exploiting the S′ region Stabilizes the Hepatitis C virus NS3 Protease Conformation in the Absence of Cofactor

Bacteriohopanetetrol from chemical degradation of an oil shale kerogen

Suzuki Coupling at the 2-Position of Densely Functionalized Pyrimidones

Substrate Specificity of the Hepatitis C Virus Serine Protease NS3

Evolution, synthesis and SAR of tripeptide α-ketoacid Inhibitors of the hepatitis C virus NS3/NS4A serine protease

α-Ketoacids Are Potent Slow Binding Inhibitors of the Hepatitis C Virus NS3 Protease

A Continuous Assay of Hepatitis C Virus Protease Based on Resonance Energy Transfer Depsipeptide Substrates

Enhancement of intestinal absorption of 2-methyl cytidine prodrugs

SAR and pharmacokinetic studies on phenethylamide inhibitors of the hepatitis C virus NS3/NS4A serine protease

Synthesis of Ethynylcyclopropanes from Epoxides

Hepatitis C virus protease inhibitors: current progress and future challenges

Application of intramolecular Heck reactions to the preparation of steroid and terpene intermediates having cis A-B ring fusions. Model studies for the total synthesis of complex cardenolides

Probing the Active Site of the Hepatitis C Virus Serine Protease by Fluorescence Resonance Energy Transfer

Synthesis of vinylcyclopropanes from epoxides

3-Methoxy-1-phenylthio-1-propene as d1 / d3 Synthon: Application for an Asymmetric Synthesis of (S)-(+)-Parasorbic Acid

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