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A local QSAR model based on the stability of nitrenium ions to support the ICH M7 expert review on the mutagenicity of primary aromatic amines

Genes and environment, 2022-03, Vol.44 (1), p.10-10, Article 10

2022

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In Silico Prediction of hPXR Activators Using Structure-Based Pharmacophore Modeling

Journal of pharmaceutical sciences, 2017-07, Vol.106 (7), p.1752-1759

2017

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Effects of the inhibition of intestinal P-glycoprotein on aliskiren pharmacokinetics in cynomolgus monkeys

Biopharmaceutics & drug disposition, 2015-01, Vol.36 (1), p.15-33

2015

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Cytochrome P450 1A2 Messenger RNA is a More Reliable Marker than Cytochrome P450 1A2 Activity, Phenacetin O-Deethylation, for Assessment of Induction Potential of Drug-Metabolizing Enzymes Using HepaRG Cells

Drug metabolism letters, 2018, Vol.12 (1), p.14-23

2018

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New Screening Criteria Setting on Evaluation of Cytochrome P450 Induction Using HepaRG Cells with Multiplex Branched DNA Technologies in Early Drug Discovery

Drug metabolism letters, 2016-09, Vol.10 (3), p.152-160

2016

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Transport and inhibition mechanism of the human SGLT2-MAP17 glucose transporter

Nature structural & molecular biology, 2024-01, Vol.31 (1), p.159-169

2024

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Direct Interaction between Substrates and Endogenous Steroids in the Active Site May Change the Activity of Cytochrome P450 3A4

Biochemistry (Easton), 2003-12, Vol.42 (51), p.15068-15077

2003

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CYP3A4 and CYP3A7-mediated carbamazepine 10,11-epoxidation are activated by differential endogenous steroids

Drug metabolism and disposition, 2003-04, Vol.31 (4), p.432-438

2003

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A local QSAR model based on the stability of nitrenium ions to support the ICH M7 expert review on the mutagenicity of primary aromatic amines

Genes and Environment, 2022, Vol.44 (10), p.1-10

2022

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Development of Simplified in Vitro P‑Glycoprotein Substrate Assay and in Silico Prediction Models To Evaluate Transport Potential of P‑Glycoprotein

Molecular pharmaceutics, 2019-05, Vol.16 (5), p.1851-1863

2019

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Development of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and Inhibition

Drug metabolism and disposition, 2021-09, Vol.49 (9), p.822-832

2021

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New Screening Criteria Setting on Evaluation of Cytochrome P450 Induction Using HepaRG Cells with Multiplex Branched DNA Technologies in Early Drug Discovery

Drug metabolism letters, 2016, Vol.10 (3), p.152

2016

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Utilization of Artificial Intelligence to Develop a QSAR Model for Predicting P450 Mediated Metabolic Stability

The FASEB journal, 2018-04, Vol.32 (S1), p.529.8-529.8

2018

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Helices F-G are important for the substrate specificities of CYP3A7

Drug metabolism and disposition, 2007-03, Vol.35 (3), p.484-492

2007

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Theoretical calculation of triazolam hydroxylation and endogenous steroid inhibition in the active site of CYP3A4

Biochimica et biophysica acta, 2007-02, Vol.1774 (2), p.223-232

2007

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シトクロムP-450の活性化はなぜ起こる?(E・医療薬科学)

ファルマシア, 2005/04/01, Vol.41(4), pp.349-350

鳥本, 奈緒

2005

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Discrimination of the active crystalline phases in anatase–rutile mixed titanium( iv ) oxide photocatalysts through action spectrum analyses

Physical chemistry chemical physics : PCCP, 2002-01, Vol.4 (23), p.5910-5914

2002

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Detection of Moisture Adsorption on Joining Surface Using Static Electricity Distribution

ECS transactions, 2017-01, Vol.75 (48), p.33-38

2017

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A local QSAR model based on the stability of nitrenium ions to support the ICH M7 expert review on the mutagenicity of primary aromatic amines

In Silico Prediction of hPXR Activators Using Structure-Based Pharmacophore Modeling

Effects of the inhibition of intestinal P-glycoprotein on aliskiren pharmacokinetics in cynomolgus monkeys

Cytochrome P450 1A2 Messenger RNA is a More Reliable Marker than Cytochrome P450 1A2 Activity, Phenacetin O-Deethylation, for Assessment of Induction Potential of Drug-Metabolizing Enzymes Using HepaRG Cells

New Screening Criteria Setting on Evaluation of Cytochrome P450 Induction Using HepaRG Cells with Multiplex Branched DNA Technologies in Early Drug Discovery

Transport and inhibition mechanism of the human SGLT2-MAP17 glucose transporter

Direct Interaction between Substrates and Endogenous Steroids in the Active Site May Change the Activity of Cytochrome P450 3A4

CYP3A4 and CYP3A7-mediated carbamazepine 10,11-epoxidation are activated by differential endogenous steroids

A local QSAR model based on the stability of nitrenium ions to support the ICH M7 expert review on the mutagenicity of primary aromatic amines

Development of Simplified in Vitro P‑Glycoprotein Substrate Assay and in Silico Prediction Models To Evaluate Transport Potential of P‑Glycoprotein

Development of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and Inhibition

New Screening Criteria Setting on Evaluation of Cytochrome P450 Induction Using HepaRG Cells with Multiplex Branched DNA Technologies in Early Drug Discovery

Utilization of Artificial Intelligence to Develop a QSAR Model for Predicting P450 Mediated Metabolic Stability

Helices F-G are important for the substrate specificities of CYP3A7

Theoretical calculation of triazolam hydroxylation and endogenous steroid inhibition in the active site of CYP3A4

シトクロムP-450の活性化はなぜ起こる?(E・医療薬科学)

Discrimination of the active crystalline phases in anatase–rutile mixed titanium( iv ) oxide photocatalysts through action spectrum analyses

Detection of Moisture Adsorption on Joining Surface Using Static Electricity Distribution

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