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TMEM16A Inhibitors Reveal TMEM16A as a Minor Component of Calcium-activated Chloride Channel Conductance in Airway and Intestinal Epithelial Cells

The Journal of biological chemistry, 2011-01, Vol.286 (3), p.2365-2374

2011

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Ani9, A Novel Potent Small-Molecule ANO1 Inhibitor with Negligible Effect on ANO2

PloS one, 2016-05, Vol.11 (5), p.e0155771-e0155771

2016

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Synthetic ion transporters can induce apoptosis by facilitating chloride anion transport into cells

Nature chemistry, 2014-10, Vol.6 (10), p.885

2014

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PAR4-Mediated PI3K/Akt and RhoA/ROCK Signaling Pathways Are Essential for Thrombin-Induced Morphological Changes in MEG-01 Cells

International journal of molecular sciences, 2022-01, Vol.23 (2), p.776

2022

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Small‐molecule activators of TMEM16A, a calcium‐activated chloride channel, stimulate epithelial chloride secretion and intestinal contraction

The FASEB journal, 2011-11, Vol.25 (11), p.4048-4062

2011

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Cinobufagin Exerts Anticancer Activity in Oral Squamous Cell Carcinoma Cells through Downregulation of ANO1

International journal of molecular sciences, 2021-11, Vol.22 (21), p.12037

2021

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Berbamine Reduces Chloroquine-Induced Itch in Mice through Inhibition of MrgprX1

International journal of molecular sciences, 2022-11, Vol.23 (22), p.14321

2022

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VI-116, A Novel Potent Inhibitor of VRAC with Minimal Effect on ANO1

International journal of molecular sciences, 2022-05, Vol.23 (9), p.5168

2022

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Synthesis and biological evaluation of novel Ani9 derivatives as potent and selective ANO1 inhibitors

European journal of medicinal chemistry, 2018-12, Vol.160, p.245-255

2018

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Crofelemer, an Antisecretory Antidiarrheal Proanthocyanidin Oligomer Extracted from Croton lechleri, Targets Two Distinct Intestinal Chloride Channels

Molecular pharmacology, 2010-01, Vol.77 (1), p.69-78

2010

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Inhibition of ANO1 by Cis - and Trans -Resveratrol and Their Anticancer Activity in Human Prostate Cancer PC-3 Cells

International journal of molecular sciences, 2023-01, Vol.24 (2), p.1186

2023

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Inhibition of Ca²⁺-activated Cl⁻ channels by gallotannins as a possible molecular basis for health benefits of red wine and green tea

The FASEB journal, 2010-11, Vol.24 (11), p.4178-4186

2010

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Inhibition of ANO1 by luteolin and its cytotoxicity in human prostate cancer PC-3 cells

PloS one, 2017-03, Vol.12 (3), p.e0174935-e0174935

2017

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GB83, an Agonist of PAR2 with a Unique Mechanism of Action Distinct from Trypsin and PAR2-AP

International journal of molecular sciences, 2022-09, Vol.23 (18), p.10631

2022

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Anticancer Effect of Hemin through ANO1 Inhibition in Human Prostate Cancer Cells

International journal of molecular sciences, 2024-06, Vol.25 (11), p.6032

2024

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Small-Molecule Screen Identifies Inhibitors of a Human Intestinal Calcium-Activated Chloride Channel

Molecular pharmacology, 2008-03, Vol.73 (3), p.758-768

2008

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Inhibition of ANO1/TMEM16A Chloride Channel by Idebenone and Its Cytotoxicity to Cancer Cell Lines

PloS one, 2015-07, Vol.10 (7), p.e0133656-e0133656

2015

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Imidazole-Based Small Molecules that Promote Neurogenesis in Pluripotent Cells

Angewandte Chemie (International ed.), 2014-08, Vol.53 (35), p.9271-9274

International ed. in English, 2014

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Diethylstilbestrol, a Novel ANO1 Inhibitor, Exerts an Anticancer Effect on Non-Small Cell Lung Cancer via Inhibition of ANO1

International journal of molecular sciences, 2021-07, Vol.22 (13), p.7100

2021

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Synthesis and Biological Evaluation of a Fused Structure of Indolizine and Pyrrolo[1,2-c]pyrimidine: Identification of Its Potent Anticancer Activity against Liver Cancer Cells

Pharmaceuticals (Basel, Switzerland), 2022-11, Vol.15 (11), p.1395

2022

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Gestodene, a novel positive allosteric modulator of PAR1, enhances PAR1-mediated human platelet aggregation

Frontiers in pharmacology, 2024-07, Vol.15, p.1430548

2024

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Isorhamnetin Ameliorates Dry Eye Disease via CFTR Activation in Mice

International journal of molecular sciences, 2021-04, Vol.22 (8), p.3954

2021

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Overlooked KCNQ4 variants augment the risk of hearing loss

Experimental and Molecular Medicine, 2023, 55(0), , pp.844-859

2023

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Improvement of NASH and liver fibrosis through modulation of the gut-liver axis by a novel intestinal FXR agonist

Biomedicine & pharmacotherapy, 2024-04, Vol.173, p.116331-116331, Article 116331

2024

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Anti-Inflammatory Effect of Licochalcone A via Regulation of ORAI1 and K+ Channels in T-Lymphocytes

International journal of molecular sciences, 2021-10, Vol.22 (19), p.10847

2021

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TMEM16A Inhibitors Reveal TMEM16A as a Minor Component of Calcium-activated Chloride Channel Conductance in Airway and Intestinal Epithelial Cells

Ani9, A Novel Potent Small-Molecule ANO1 Inhibitor with Negligible Effect on ANO2

Synthetic ion transporters can induce apoptosis by facilitating chloride anion transport into cells

PAR4-Mediated PI3K/Akt and RhoA/ROCK Signaling Pathways Are Essential for Thrombin-Induced Morphological Changes in MEG-01 Cells

Small‐molecule activators of TMEM16A, a calcium‐activated chloride channel, stimulate epithelial chloride secretion and intestinal contraction

Cinobufagin Exerts Anticancer Activity in Oral Squamous Cell Carcinoma Cells through Downregulation of ANO1

Berbamine Reduces Chloroquine-Induced Itch in Mice through Inhibition of MrgprX1

VI-116, A Novel Potent Inhibitor of VRAC with Minimal Effect on ANO1

Synthesis and biological evaluation of novel Ani9 derivatives as potent and selective ANO1 inhibitors

Crofelemer, an Antisecretory Antidiarrheal Proanthocyanidin Oligomer Extracted from Croton lechleri, Targets Two Distinct Intestinal Chloride Channels

Inhibition of ANO1 by Cis - and Trans -Resveratrol and Their Anticancer Activity in Human Prostate Cancer PC-3 Cells

Inhibition of Ca²⁺-activated Cl⁻ channels by gallotannins as a possible molecular basis for health benefits of red wine and green tea

Inhibition of ANO1 by luteolin and its cytotoxicity in human prostate cancer PC-3 cells

GB83, an Agonist of PAR2 with a Unique Mechanism of Action Distinct from Trypsin and PAR2-AP

Anticancer Effect of Hemin through ANO1 Inhibition in Human Prostate Cancer Cells

Small-Molecule Screen Identifies Inhibitors of a Human Intestinal Calcium-Activated Chloride Channel

Inhibition of ANO1/TMEM16A Chloride Channel by Idebenone and Its Cytotoxicity to Cancer Cell Lines

Imidazole-Based Small Molecules that Promote Neurogenesis in Pluripotent Cells

Diethylstilbestrol, a Novel ANO1 Inhibitor, Exerts an Anticancer Effect on Non-Small Cell Lung Cancer via Inhibition of ANO1

Synthesis and Biological Evaluation of a Fused Structure of Indolizine and Pyrrolo[1,2-c]pyrimidine: Identification of Its Potent Anticancer Activity against Liver Cancer Cells

Gestodene, a novel positive allosteric modulator of PAR1, enhances PAR1-mediated human platelet aggregation

Isorhamnetin Ameliorates Dry Eye Disease via CFTR Activation in Mice

Overlooked KCNQ4 variants augment the risk of hearing loss

Improvement of NASH and liver fibrosis through modulation of the gut-liver axis by a novel intestinal FXR agonist

Anti-Inflammatory Effect of Licochalcone A via Regulation of ORAI1 and K+ Channels in T-Lymphocytes

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