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Insulin as a key autoantigen in the development of type 1 diabetes

Diabetes/metabolism research and reviews, 2011-11, Vol.27 (8), p.773-777

Nakayama, Maki

2011

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Using the T Cell Receptor as a Biomarker in Type 1 Diabetes

Frontiers in immunology, 2021-11, Vol.12, p.777788-777788

2021

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Hybrid Insulin Peptides Are Autoantigens in Type 1 Diabetes

Diabetes (New York, N.Y.), 2019-09, Vol.68 (9), p.1830-1840

2019

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Krüppel-like factor 1 is a core cardiomyogenic trigger in zebrafish

Science (American Association for the Advancement of Science), 2021-04, Vol.372 (6538), p.201-205

2021

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The MicroRNA miR-181 Is a Critical Cellular Metabolic Rheostat Essential for NKT Cell Ontogenesis and Lymphocyte Development and Homeostasis

Immunity (Cambridge, Mass.), 2013-05, Vol.38 (5), p.984-997

2013

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Specificity and detection of insulin-reactive CD4⁺ T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse

Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (40), p.16729-16734

2011

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Germline-like TCR-α chains shared between autoreactive T cells in blood and pancreas

Nature communications, 2024-06, Vol.15 (1), p.4971-16

2024

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Zebrafish FOXP3 is required for the maintenance of immune tolerance

Developmental and comparative immunology, 2017-08, Vol.73, p.156-162

2017

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Determining Antigen Specificity of Human Islet Infiltrating T Cells in Type 1 Diabetes

Frontiers in immunology, 2019-03, Vol.10, p.365-365

2019

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Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice

Nature, 2005-05, Vol.435 (7039), p.220-223

2005

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High-dose dexamethasone therapy as the initial treatment for idiopathic thrombocytopenic purpura

International journal of hematology, 2020-03, Vol.111 (3), p.388-395

2020

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Characterization of Human CD4 T Cells Specific for a C-Peptide/C-Peptide Hybrid Insulin Peptide

Frontiers in immunology, 2021-05, Vol.12, p.668680-668680

2021

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Regulatory vs. inflammatory cytokine T-cell responses to mutated insulin peptides in healthy and type 1 diabetic subjects

Proceedings of the National Academy of Sciences - PNAS, 2015-04, Vol.112 (14), p.4429-4434

2015

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Excessive Th1 responses due to the absence of TGF-β signaling cause autoimmune diabetes and dysregulated Treg cell homeostasis

Proceedings of the National Academy of Sciences - PNAS, 2013-04, Vol.110 (17), p.6961-6966

2013

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Multiplex T Cell Stimulation Assay Utilizing a T Cell Activation Reporter-Based Detection System

Frontiers in immunology, 2020-04, Vol.11, p.633-633

2020

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Insulin B-chain hybrid peptides are agonists for T cells reactive to insulin B:9-23 in autoimmune diabetes

Frontiers in immunology, 2022-08, Vol.13, p.926650

2022

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Monoclonal antibody blocking the recognition of an insulin peptide–MHC complex modulates type 1 diabetes

Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (7), p.2656-2661

2014

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Proinsulin-Reactive CD4 T Cells in the Islets of Type 1 Diabetes Organ Donors

Frontiers in endocrinology (Lausanne), 2021-03, Vol.12, p.622647-622647

2021

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In Vitro Selection of Highly Darunavir-Resistant and Replication-Competent HIV-1 Variants by Using a Mixture of Clinical HIV-1 Isolates Resistant to Multiple Conventional Protease Inhibitors

Journal of Virology, 2010-11, Vol.84 (22), p.11961-11969

2010

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Single-cell RNAseq identifies clonally expanded antigen-specific T-cells following intradermal injection of gold nanoparticles loaded with diabetes autoantigen in humans

Frontiers in immunology, 2023, Vol.14, p.1276255

2023

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The somatically generated portion of T cell receptor CDR3α contributes to the MHC allele specificity of the T cell receptor

eLife, 2017-11, Vol.6

2017

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Structure-based selection of small molecules to alter allele-specific MHC class II antigen presentation

The Journal of immunology (1950), 2011-12, Vol.187 (11), p.5921-5930

2011

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Molecular Interactions Governing Autoantigen Presentation in Type 1 Diabetes

Current Diabetes Reports, 2015-12, Vol.15 (12), p.113-113, Article 113

2015

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Multiplex T-cell Stimulation Assay Utilizing a T-cell Activation Reporter-based Detection System

Bio-protocol, 2021-01, Vol.11 (2), p.e3883-e3883

2021

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Temporal development of T cell receptor repertoires during childhood in health and disease

JCI insight, 2022-09, Vol.7 (18)

2022

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Insulin as a key autoantigen in the development of type 1 diabetes

Using the T Cell Receptor as a Biomarker in Type 1 Diabetes

Hybrid Insulin Peptides Are Autoantigens in Type 1 Diabetes

Krüppel-like factor 1 is a core cardiomyogenic trigger in zebrafish

The MicroRNA miR-181 Is a Critical Cellular Metabolic Rheostat Essential for NKT Cell Ontogenesis and Lymphocyte Development and Homeostasis

Specificity and detection of insulin-reactive CD4⁺ T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse

Germline-like TCR-α chains shared between autoreactive T cells in blood and pancreas

Zebrafish FOXP3 is required for the maintenance of immune tolerance

Determining Antigen Specificity of Human Islet Infiltrating T Cells in Type 1 Diabetes

Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice

High-dose dexamethasone therapy as the initial treatment for idiopathic thrombocytopenic purpura

Characterization of Human CD4 T Cells Specific for a C-Peptide/C-Peptide Hybrid Insulin Peptide

Regulatory vs. inflammatory cytokine T-cell responses to mutated insulin peptides in healthy and type 1 diabetic subjects

Excessive Th1 responses due to the absence of TGF-β signaling cause autoimmune diabetes and dysregulated Treg cell homeostasis

Multiplex T Cell Stimulation Assay Utilizing a T Cell Activation Reporter-Based Detection System

Insulin B-chain hybrid peptides are agonists for T cells reactive to insulin B:9-23 in autoimmune diabetes

Monoclonal antibody blocking the recognition of an insulin peptide–MHC complex modulates type 1 diabetes

Proinsulin-Reactive CD4 T Cells in the Islets of Type 1 Diabetes Organ Donors

In Vitro Selection of Highly Darunavir-Resistant and Replication-Competent HIV-1 Variants by Using a Mixture of Clinical HIV-1 Isolates Resistant to Multiple Conventional Protease Inhibitors

Single-cell RNAseq identifies clonally expanded antigen-specific T-cells following intradermal injection of gold nanoparticles loaded with diabetes autoantigen in humans

The somatically generated portion of T cell receptor CDR3α contributes to the MHC allele specificity of the T cell receptor

Structure-based selection of small molecules to alter allele-specific MHC class II antigen presentation

Molecular Interactions Governing Autoantigen Presentation in Type 1 Diabetes

Multiplex T-cell Stimulation Assay Utilizing a T-cell Activation Reporter-based Detection System

Temporal development of T cell receptor repertoires during childhood in health and disease

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