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The new-generation selective ROS1/NTRK inhibitor DS-6051b overcomes crizotinib resistant ROS1-G2032R mutation in preclinical models

Nature communications, 2019-08, Vol.10 (1), p.3604-12, Article 3604

2019

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Novel LCAT (Lecithin:Cholesterol Acyltransferase) Activator DS-8190a Prevents the Progression of Plaque Accumulation in Atherosclerosis Models

Arteriosclerosis, thrombosis, and vascular biology, 2021-01, Vol.41 (1), p.360-376

2021

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Four cases of cytokine storm after COVID-19 vaccination: Case report

Frontiers in immunology, 2022-08, Vol.13

2022

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Comparison of therapeutic effects of mesenchymal stem cells derived from superficial and deep subcutaneous adipose tissues

Stem cell research & therapy, 2023-05, Vol.14 (1), p.121-121, Article 121

2023

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Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT

Communications chemistry, 2019-02, Vol.2 (1), Article 20

2019

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Identification of the fused bicyclic 4-amino-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors

Bioorganic & medicinal chemistry letters, 2013-06, Vol.23 (11), p.3325-3328

2013

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Reassessment of the unique mode of binding between angiotensin II type 1 receptor and their blockers

PloS one, 2013-11, Vol.8 (11), p.e79914

2013

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Synthesis and biological evaluation of 5-carbamoyl-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors

Bioorganic & medicinal chemistry, 2013-11, Vol.21 (22), p.7025-7037

2013

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Identification of the 5,5-dioxo-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine derivatives as highly selective PDE4B inhibitors

Bioorganic & medicinal chemistry letters, 2014-02, Vol.24 (3), p.893-899

2014

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Small molecules with similar structures exhibit agonist, neutral antagonist or inverse agonist activity toward angiotensin II type 1 receptor

PloS one, 2012-06, Vol.7 (6), p.e37974-e37974

2012

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Path Planning and Traveling Control for Pesticide-Spraying Robot in Greenhouse

Journal of Signal Processing, 2017/07/20, Vol.21(4), pp.175-178

2017

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Clinical and genetic characterizations of 16q-linked autosomal dominant spinocerebellar ataxia (AD-SCA) and frequency analysis of AD-SCA in the Japanese population

Movement disorders, 2007-04, Vol.22 (6), p.857-862

2007

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U.S. Phase I First-in-human Study of Taletrectinib (DS-6051b/AB-106), a ROS1/TRK Inhibitor, in Patients with Advanced Solid Tumors

Clinical cancer research, 2020-09, Vol.26 (18), p.4785-4794

2020

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Age estimation using post-mortem computed tomography and fetal dental radiographic findings in an early to mid-pregnancy fetus: A case report

Legal medicine (Tokyo, Japan), 2023-05, Vol.62, p.102232, Article 102232

2023

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Multiple Endocrine Neoplasia Type I and Cushing's Syndrome Due to an Aggressive ACTH Producing Thymic Carcinoid

Internal Medicine, 2006, Vol.45(2), pp.81-86

2006

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Dental radiographic information of term newborn babies within the first month: Analyzing five radiographic cases along with physical attributes in Japan

Legal medicine (Tokyo, Japan), 2023-02, Vol.60, p.102171-102171, Article 102171

2023

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A covalent fragment-based strategy targeting a novel cysteine to inhibit activity of mutant EGFR kinase

RSC medicinal chemistry, 2023-12, Vol.14 (12), p.2731-2737

2023

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(R) salsolinol N-methyltransferase activity increases in parkinsonian lymphocytes

Annals of neurology, 1998-02, Vol.43 (2), p.212-216

1998

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Growth Hormone Insensitivity Syndrome Associated with Syringomyelia and Type I Chiari Malformation

Internal Medicine, 2003, Vol.42(11), pp.1117-1121

2003

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A case of cerebral infarction due to invasive sino-orbital aspergillosis

Nōsotchū, 2019, Vol.41 (6), p.515-519

2019

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The First Example of Enantioselective Protonation of Prochiral Enolates with Chiral γ -Hydroxyselenoxides

Chemistry letters, 1996-01, Vol.25 (3), p.207-208

1996

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非天然骨格を有する新規CERT阻害薬の創成：産学官連携による成果創出

ファルマシア, 2021, Vol.57(12), pp.1108-1112

2021

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Correction: Small Molecules with Similar Structures Exhibit Agonist, Neutral Antagonist or Inverse Agonist Activity toward Angiotensin II Type 1 Receptor

PloS one, 2013-05, Vol.8 (5)

2013

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Markedly improving sarcoid cervical myelopathy after the diagnostic treatment of prednisolone, associated with highly spondylotic spines

Nihon Naika Gakkai Zasshi, 2004/07/10, Vol.93(7), pp.1436-1438

2004

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Abnormal bowel movement

Nihon rinshō, 2002-04, Vol.60 Suppl 4, p.553

Nakao, Naoki

2002

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The new-generation selective ROS1/NTRK inhibitor DS-6051b overcomes crizotinib resistant ROS1-G2032R mutation in preclinical models

Novel LCAT (Lecithin:Cholesterol Acyltransferase) Activator DS-8190a Prevents the Progression of Plaque Accumulation in Atherosclerosis Models

Four cases of cytokine storm after COVID-19 vaccination: Case report

Comparison of therapeutic effects of mesenchymal stem cells derived from superficial and deep subcutaneous adipose tissues

Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT

Identification of the fused bicyclic 4-amino-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors

Reassessment of the unique mode of binding between angiotensin II type 1 receptor and their blockers

Synthesis and biological evaluation of 5-carbamoyl-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors

Identification of the 5,5-dioxo-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine derivatives as highly selective PDE4B inhibitors

Small molecules with similar structures exhibit agonist, neutral antagonist or inverse agonist activity toward angiotensin II type 1 receptor

Path Planning and Traveling Control for Pesticide-Spraying Robot in Greenhouse

Clinical and genetic characterizations of 16q-linked autosomal dominant spinocerebellar ataxia (AD-SCA) and frequency analysis of AD-SCA in the Japanese population

U.S. Phase I First-in-human Study of Taletrectinib (DS-6051b/AB-106), a ROS1/TRK Inhibitor, in Patients with Advanced Solid Tumors

Age estimation using post-mortem computed tomography and fetal dental radiographic findings in an early to mid-pregnancy fetus: A case report

Multiple Endocrine Neoplasia Type I and Cushing's Syndrome Due to an Aggressive ACTH Producing Thymic Carcinoid

Dental radiographic information of term newborn babies within the first month: Analyzing five radiographic cases along with physical attributes in Japan

A covalent fragment-based strategy targeting a novel cysteine to inhibit activity of mutant EGFR kinase

(R) salsolinol N-methyltransferase activity increases in parkinsonian lymphocytes

Growth Hormone Insensitivity Syndrome Associated with Syringomyelia and Type I Chiari Malformation

A case of cerebral infarction due to invasive sino-orbital aspergillosis

The First Example of Enantioselective Protonation of Prochiral Enolates with Chiral γ -Hydroxyselenoxides

非天然骨格を有する新規CERT阻害薬の創成：産学官連携による成果創出

Correction: Small Molecules with Similar Structures Exhibit Agonist, Neutral Antagonist or Inverse Agonist Activity toward Angiotensin II Type 1 Receptor

Markedly improving sarcoid cervical myelopathy after the diagnostic treatment of prednisolone, associated with highly spondylotic spines

Abnormal bowel movement

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