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Mechanism of allosteric modulation of P-glycoprotein by transport substrates and inhibitors

Science (American Association for the Advancement of Science), 2019-05, Vol.364 (6441), p.689-692

2019

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Energy transduction and alternating access of the mammalian ABC transporter P-glycoprotein

Nature (London), 2017-03, Vol.543 (7647), p.738-741

2017

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Endocytosis Pathways of Endothelial Cell Derived Exosomes

Molecular pharmaceutics, 2018-12, Vol.15 (12), p.5585-5590

2018

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In vitro evaluation of endothelial exosomes as carriers for small interfering ribonucleic acid delivery

International journal of nanomedicine, 2014-01, Vol.9, p.4223-4230

2014

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Development of in vivo HDX‐MS with applications to a TonB‐dependent transporter and other proteins

Protein science, 2022-09, Vol.31 (9), p.e4402-n/a

2022

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Conformational Transitions and Alternating-Access Mechanism in the Sarcoplasmic Reticulum Calcium Pump

Journal of molecular biology, 2017-03, Vol.429 (5), p.647-666

2017

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Proton Countertransport and Coupled Gating in the Sarcoplasmic Reticulum Calcium Pump

Journal of molecular biology, 2018-12, Vol.430 (24), p.5050-5065

2018

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The mechanism of rotating proton pumping ATPases

Biochimica et biophysica acta, 2010-08, Vol.1797 (8), p.1343-1352

2010

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Rotational catalysis in proton pumping ATPases: From E. coli F-ATPase to mammalian V-ATPase

Biochimica et biophysica acta, 2012-10, Vol.1817 (10), p.1711-1721

2012

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A disulfide chaperone knockout facilitates spin labeling and pulse EPR spectroscopy of outer membrane transporters

Protein science, 2023-07, Vol.32 (7), p.e4704-n/a

2023

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Disulfide Chaperone Knockouts Enable In Vivo Double Spin Labeling of an Outer Membrane Transporter

Biophysical journal, 2019-10, Vol.117 (8), p.1476-1484

2019

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Mechanistic insights and therapeutic opportunities of antimicrobial chemokines

Seminars in cell & developmental biology, 2019-04, Vol.88, p.119-128

2019

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In vitro fusion of single synaptic and dense core vesicles reproduces key physiological properties

Nature communications, 2019-08, Vol.10 (1), p.3904-11, Article 3904

2019

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CXCL10 Acts as a Bifunctional Antimicrobial Molecule against Bacillus anthracis

mBio, 2016-05, Vol.7 (3)

2016

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The rotary mechanism of the ATP synthase

Archives of biochemistry and biophysics, 2008-08, Vol.476 (1), p.43-50

2008

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MAPK Phosphorylation of Connexin 43 Promotes Binding of Cyclin E and Smooth Muscle Cell Proliferation

Circulation research, 2012-07, Vol.111 (2), p.201-211

2012

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Single Molecule Behavior of Inhibited and Active States of Escherichia coli ATP Synthase F1 Rotation

The Journal of biological chemistry, 2010-12, Vol.285 (53), p.42058-42067

2010

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Binding of Phytopolyphenol Piceatannol Disrupts β/γ Subunit Interactions and Rate-limiting Step of Steady-state Rotational Catalysis in Escherichia coli F1-ATPase

The Journal of biological chemistry, 2012-06, Vol.287 (27), p.22771-22780

2012

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Citryl Ornithine Is an Intermediate in a Three-Step Biosynthetic Pathway for Rhizoferrin in Francisella

ACS chemical biology, 2019-08, Vol.14 (8), p.1760-1766

2019

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Escherichia coli Pyruvate Dehydrogenase Complex Is an Important Component of CXCL10-Mediated Antimicrobial Activity

Infection and immunity, 2016-01, Vol.84 (1), p.320-328

2016

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Bacillus anthracis Peptidoglycan Integrity Is Disrupted by the Chemokine CXCL10 through the FtsE/X Complex

Frontiers in microbiology, 2017-04, Vol.8, p.740-740

2017

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13C NMR detects conformational change in the 100-kD membrane transporter ClC-ec1

Journal of biomolecular NMR, 2015-04, Vol.61 (3-4), p.209-226

2015

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Temperature Dependence of Single Molecule Rotation of the Escherichia coli ATP Synthase F1 Sector Reveals the Importance of γ-β Subunit Interactions in the Catalytic Dwell

The Journal of biological chemistry, 2009-08, Vol.284 (33), p.22401-22410

2009

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Genetic selection system for improving recombinant membrane protein expression in E. coli

Protein science, 2009-02, Vol.18 (2), p.372-383

2009

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A Rotor-Stator Cross-link in the F1-ATPase Blocks the Rate-limiting Step of Rotational Catalysis

The Journal of biological chemistry, 2008-09, Vol.283 (38), p.26228-26240

2008

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Mechanism of allosteric modulation of P-glycoprotein by transport substrates and inhibitors

Energy transduction and alternating access of the mammalian ABC transporter P-glycoprotein

Endocytosis Pathways of Endothelial Cell Derived Exosomes

In vitro evaluation of endothelial exosomes as carriers for small interfering ribonucleic acid delivery

Development of in vivo HDX‐MS with applications to a TonB‐dependent transporter and other proteins

Conformational Transitions and Alternating-Access Mechanism in the Sarcoplasmic Reticulum Calcium Pump

Proton Countertransport and Coupled Gating in the Sarcoplasmic Reticulum Calcium Pump

The mechanism of rotating proton pumping ATPases

Rotational catalysis in proton pumping ATPases: From E. coli F-ATPase to mammalian V-ATPase

A disulfide chaperone knockout facilitates spin labeling and pulse EPR spectroscopy of outer membrane transporters

Disulfide Chaperone Knockouts Enable In Vivo Double Spin Labeling of an Outer Membrane Transporter

Mechanistic insights and therapeutic opportunities of antimicrobial chemokines

In vitro fusion of single synaptic and dense core vesicles reproduces key physiological properties

CXCL10 Acts as a Bifunctional Antimicrobial Molecule against Bacillus anthracis

The rotary mechanism of the ATP synthase

MAPK Phosphorylation of Connexin 43 Promotes Binding of Cyclin E and Smooth Muscle Cell Proliferation

Single Molecule Behavior of Inhibited and Active States of Escherichia coli ATP Synthase F1 Rotation

Binding of Phytopolyphenol Piceatannol Disrupts β/γ Subunit Interactions and Rate-limiting Step of Steady-state Rotational Catalysis in Escherichia coli F1-ATPase

Citryl Ornithine Is an Intermediate in a Three-Step Biosynthetic Pathway for Rhizoferrin in Francisella

Escherichia coli Pyruvate Dehydrogenase Complex Is an Important Component of CXCL10-Mediated Antimicrobial Activity

Bacillus anthracis Peptidoglycan Integrity Is Disrupted by the Chemokine CXCL10 through the FtsE/X Complex

13C NMR detects conformational change in the 100-kD membrane transporter ClC-ec1

Temperature Dependence of Single Molecule Rotation of the Escherichia coli ATP Synthase F1 Sector Reveals the Importance of γ-β Subunit Interactions in the Catalytic Dwell

Genetic selection system for improving recombinant membrane protein expression in E. coli

A Rotor-Stator Cross-link in the F1-ATPase Blocks the Rate-limiting Step of Rotational Catalysis

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