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RNA-Based Vaccines in Cancer Immunotherapy

Journal of Immunology Research, 2015-01, Vol.2015 (2015), p.1-9

2015

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Transfection efficiency and transgene expression kinetics of mRNA delivered in naked and nanoparticle format

Journal of controlled release, 2013-03, Vol.166 (3), p.227-233

2013

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Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy

Nature communications, 2021-01, Vol.12 (1), p.352-352, Article 352

2021

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Viral infection of cells within the tumor microenvironment mediates antitumor immunotherapy via selective TBK1-IRF3 signaling

Nature communications, 2021-03, Vol.12 (1), p.1858-1858, Article 1858

2021

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Examining Peripheral and Tumor Cellular Immunome in Patients With Cancer

Frontiers in immunology, 2019-07, Vol.10, p.1767-1767

2019

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Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity

Scientific reports, 2014-06, Vol.4 (1), Article 5128

2014

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Genetically stable poliovirus vectors activate dendritic cells and prime antitumor CD8 T cell immunity

Nature communications, 2020-01, Vol.11 (1), p.524-524, Article 524

2020

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Targeting Tumor Acidosis and Regulatory T Cells Unmasks Anti-Metastatic Potential of Local Tumor Ablation in Triple-Negative Breast Cancer

International journal of molecular sciences, 2022-08, Vol.23 (15), p.8479

2022

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Polyethylene Glycol‐Like Brush Polymer Conjugate of a Protein Drug Does Not Induce an Antipolymer Immune Response and Has Enhanced Pharmacokinetics than Its Polyethylene Glycol Counterpart

Advanced science, 2022-04, Vol.9 (11), p.e2103672-n/a

2022

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Phase I trial of intratumoral PVSRIPO in patients with unresectable, treatment-refractory melanoma

Journal for immunotherapy of cancer, 2021-04, Vol.9 (4), p.e002203

2021

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A pilot study of IL-2Rα blockade during lymphopenia depletes regulatory T-cells and correlates with enhanced immunity in patients with glioblastoma

PloS one, 2012-02, Vol.7 (2), p.e31046-e31046

2012

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Breast cancer-derived DAMPs enhance cell invasion and metastasis, while nucleic acid scavengers mitigate these effects

Molecular therapy. Nucleic acids, 2021-12, Vol.26, p.1-10

2021

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Functional reprogramming of peripheral blood monocytes by soluble mediators in patients with pancreatic cancer and intraductal papillary mucinous neoplasms

Frontiers in immunology, 2023-07, Vol.14, p.1116034-1116034

2023

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Spatial biology analysis reveals B cell follicles in secondary lymphoid structures may regulate anti-tumor responses at initial melanoma diagnosis

Frontiers in immunology, 2022-08, Vol.13, p.952220-952220

2022

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Oncolytic viruses in melanoma

Frontiers in bioscience (Landmark. Print), 2022-02, Vol.27 (2), p.63-63

2022

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Recombinant Poliovirus for Cancer Immunotherapy

Annual review of medicine, 2018-01, Vol.69 (1), p.289-299

2018

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Improved efficacy against malignant brain tumors with EGFRwt/EGFRvIII targeting immunotoxin and checkpoint inhibitor combinations

Journal for immunotherapy of cancer, 2019-05, Vol.7 (1), p.142-14, Article 142

2019

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Intratumor childhood vaccine-specific CD4+ T-cell recall coordinates antitumor CD8+ T cells and eosinophils

Journal for immunotherapy of cancer, 2023-04, Vol.11 (4), p.e006463

2023

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Cancer immunotherapy with recombinant poliovirus induces IFN-dominant activation of dendritic cells and tumor antigen-specific CTLs

Science translational medicine, 2017-09, Vol.9 (408)

2017

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Multimodality analysis confers a prognostic benefit of a T-cell infiltrated tumor microenvironment and peripheral immune status in patients with melanoma

Journal for immunotherapy of cancer, 2022-09, Vol.10 (9), p.e005052

2022

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Plasmonic gold nanostars for synergistic photoimmunotherapy to treat cancer

Nanophotonics (Berlin, Germany), 2021-09, Vol.10 (12), p.3295-3302

2021

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The Quest for mRNA Vaccines

Nucleic acid therapeutics, 2022-12, Vol.32 (6), p.449-456

2022

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Systemic Anti-CD25 Monoclonal Antibody Administration Safely Enhances Immunity in Murine Glioma without Eliminating Regulatory T Cells

Clinical cancer research, 2006-07, Vol.12 (14), p.4294-4305

2006

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Cancer mRNA vaccines: clinical advances and future opportunities

Nature reviews. Clinical oncology, 2024-07, Vol.21 (7), p.489-500

2024

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Controlling cancer-induced inflammation with a nucleic acid scavenger prevents lung metastasis in murine models of breast cancer

Molecular therapy, 2021-05, Vol.29 (5), p.1772-1781

2021

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RNA-Based Vaccines in Cancer Immunotherapy

Transfection efficiency and transgene expression kinetics of mRNA delivered in naked and nanoparticle format

Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy

Viral infection of cells within the tumor microenvironment mediates antitumor immunotherapy via selective TBK1-IRF3 signaling

Examining Peripheral and Tumor Cellular Immunome in Patients With Cancer

Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity

Genetically stable poliovirus vectors activate dendritic cells and prime antitumor CD8 T cell immunity

Targeting Tumor Acidosis and Regulatory T Cells Unmasks Anti-Metastatic Potential of Local Tumor Ablation in Triple-Negative Breast Cancer

Polyethylene Glycol‐Like Brush Polymer Conjugate of a Protein Drug Does Not Induce an Antipolymer Immune Response and Has Enhanced Pharmacokinetics than Its Polyethylene Glycol Counterpart

Phase I trial of intratumoral PVSRIPO in patients with unresectable, treatment-refractory melanoma

A pilot study of IL-2Rα blockade during lymphopenia depletes regulatory T-cells and correlates with enhanced immunity in patients with glioblastoma

Breast cancer-derived DAMPs enhance cell invasion and metastasis, while nucleic acid scavengers mitigate these effects

Functional reprogramming of peripheral blood monocytes by soluble mediators in patients with pancreatic cancer and intraductal papillary mucinous neoplasms

Spatial biology analysis reveals B cell follicles in secondary lymphoid structures may regulate anti-tumor responses at initial melanoma diagnosis

Oncolytic viruses in melanoma

Recombinant Poliovirus for Cancer Immunotherapy

Improved efficacy against malignant brain tumors with EGFRwt/EGFRvIII targeting immunotoxin and checkpoint inhibitor combinations

Intratumor childhood vaccine-specific CD4+ T-cell recall coordinates antitumor CD8+ T cells and eosinophils

Cancer immunotherapy with recombinant poliovirus induces IFN-dominant activation of dendritic cells and tumor antigen-specific CTLs

Multimodality analysis confers a prognostic benefit of a T-cell infiltrated tumor microenvironment and peripheral immune status in patients with melanoma

Plasmonic gold nanostars for synergistic photoimmunotherapy to treat cancer

The Quest for mRNA Vaccines

Systemic Anti-CD25 Monoclonal Antibody Administration Safely Enhances Immunity in Murine Glioma without Eliminating Regulatory T Cells

Cancer mRNA vaccines: clinical advances and future opportunities

Controlling cancer-induced inflammation with a nucleic acid scavenger prevents lung metastasis in murine models of breast cancer

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