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Nicotinic Acid Phosphoribosyltransferase Regulates Cancer Cell Metabolism, Susceptibility to NAMPT Inhibitors, and DNA Repair

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (14), p.3857-3869

2017

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Gut microbiota severely hampers the efficacy of NAD-lowering therapy in leukemia

Cell death & disease, 2022-04, Vol.13 (4), p.320-320, Article 320

2022

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The NAD biosynthesis inhibitor APO866 has potent antitumor activity against hematologic malignancies

Blood, 2009-04, Vol.113 (14), p.3276-3286

2009

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Depletion of SIRT6 enzymatic activity increases acute myeloid leukemia cells' vulnerability to DNA-damaging agents

Haematologica (Roma), 2018-01, Vol.103 (1), p.80

2018

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Nicotinaldehyde, a Novel Precursor of NAD Biosynthesis, Abrogates the Anti-Cancer Activity of an NAD-Lowering Agent in Leukemia

Cancers, 2023-01, Vol.15 (3), p.787

2023

Volltextzugriff (PDF)

Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model

Oncotarget, 2016-01, Vol.7 (3), p.2968-2984

2016

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Anticancer Activities of Novel Nicotinamide Phosphoribosyltransferase Inhibitors in Hematological Malignancies

Molecules (Basel, Switzerland), 2023-02, Vol.28 (4), p.1897

2023

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Identification of NAPRT Inhibitors with Anti-Cancer Properties by In Silico Drug Discovery

Pharmaceuticals (Basel, Switzerland), 2022-07, Vol.15 (7), p.848

2022

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Activation of Bone Marrow-Derived Cells Angiotensin (Ang) II Type 1 Receptor by Ang II Promotes Atherosclerotic Plaque Vulnerability

International journal of molecular sciences, 2018-09, Vol.19 (9), p.2621

2018

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Nicotinamide phosphoribosyltransferase (NAMPT) inhibitors as therapeutics: rationales, controversies, clinical experience

Current drug targets, 2013-06, Vol.14 (6), p.637

2013

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The TAT-RasGAP317-326 anti-cancer peptide can kill in a caspase-, apoptosis-, and necroptosis-independent manner

Oncotarget, 2016-09, Vol.7 (39), p.64342-64359

2016

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A critical role of autophagy in antileukemia/lymphoma effects of APO866, an inhibitor of NAD biosynthesis

Autophagy, 2014-04, Vol.10 (4), p.603-617

2014

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Pneumocystis jirovecii genotype associated with increased death rate of HIV-infected patients with pneumonia

Emerging infectious diseases, 2013-01, Vol.19 (1), p.21-28

2013

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Nicotinamide phosphoribosyltransferase as a target in inflammation- related disorders

Current topics in medicinal chemistry, 2013-12, Vol.13 (23), p.2930

2013

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Imatinib Uptake into Cells is Not Mediated by Organic Cation Transporters OCT1, OCT2, or OCT3, But is Influenced by Extracellular pH

Drug metabolism letters, 2019, Vol.13 (2), p.102

2019

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Mutations of Pneumocystis jirovecii Dihydrofolate Reductase Associated with Failure of Prophylaxis

Antimicrobial Agents and Chemotherapy, 2004-11, Vol.48 (11), p.4301-4305

2004

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Molecular evidence of interhuman transmission of Pneumocystis pneumonia among renal transplant recipients hospitalized with HIV-infected patients

Emerging infectious diseases, 2004-10, Vol.10 (10), p.1766-1773

2004

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Molecular evidence of Pneumocystis transmission in pediatric transplant unit

Emerging infectious diseases, 2005-02, Vol.11 (2), p.330-332

2005

Volltextzugriff (PDF)

Anti-cancer activity of 5-O-alkyl 1,4-imino-1,4-dideoxyribitols

Bioorganic & medicinal chemistry, 2011-12, Vol.19 (24), p.7720-7727

2011

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Sulfa resistance and dihydropteroate synthase mutants in recurrent Pneumocystis carinii pneumonia

Emerging infectious diseases, 2003-07, Vol.9 (7), p.864-867

2003

Volltextzugriff (PDF)

Synthesis and structure-activity relationship of new nicotinamide phosphoribosyltransferase inhibitors with antitumor activity on solid and haematological cancer

European journal of medicinal chemistry, 2023-03, Vol.250, p.115170-115170, Article 115170

2023

Volltextzugriff (PDF)

Experimental Drainage Device to Reduce Lymphoedema in a Rat Model

European journal of vascular and endovascular surgery, 2019-06, Vol.57 (6), p.859-867

2019

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Identification of new FK866 analogues with potent anticancer activity against pancreatic cancer

European journal of medicinal chemistry, 2022-09, Vol.239, p.114504-114504, Article 114504

2022

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Genetic diversity of Pneumocystis carinii in HIV-positive and -negative patients as revealed by PCR-SSCP typing

AIDS (London), 2001-03, Vol.15 (4), p.461-466

2001

Volltextzugriff (PDF)

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Nicotinic Acid Phosphoribosyltransferase Regulates Cancer Cell Metabolism, Susceptibility to NAMPT Inhibitors, and DNA Repair

The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance

Gut microbiota severely hampers the efficacy of NAD-lowering therapy in leukemia

The NAD biosynthesis inhibitor APO866 has potent antitumor activity against hematologic malignancies

Depletion of SIRT6 enzymatic activity increases acute myeloid leukemia cells' vulnerability to DNA-damaging agents

Nicotinaldehyde, a Novel Precursor of NAD Biosynthesis, Abrogates the Anti-Cancer Activity of an NAD-Lowering Agent in Leukemia

Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model

Anticancer Activities of Novel Nicotinamide Phosphoribosyltransferase Inhibitors in Hematological Malignancies

Identification of NAPRT Inhibitors with Anti-Cancer Properties by In Silico Drug Discovery

Activation of Bone Marrow-Derived Cells Angiotensin (Ang) II Type 1 Receptor by Ang II Promotes Atherosclerotic Plaque Vulnerability

Nicotinamide phosphoribosyltransferase (NAMPT) inhibitors as therapeutics: rationales, controversies, clinical experience

The TAT-RasGAP317-326 anti-cancer peptide can kill in a caspase-, apoptosis-, and necroptosis-independent manner

A critical role of autophagy in antileukemia/lymphoma effects of APO866, an inhibitor of NAD biosynthesis

Pneumocystis jirovecii genotype associated with increased death rate of HIV-infected patients with pneumonia

Nicotinamide phosphoribosyltransferase as a target in inflammation- related disorders

Imatinib Uptake into Cells is Not Mediated by Organic Cation Transporters OCT1, OCT2, or OCT3, But is Influenced by Extracellular pH

Mutations of Pneumocystis jirovecii Dihydrofolate Reductase Associated with Failure of Prophylaxis

Molecular evidence of interhuman transmission of Pneumocystis pneumonia among renal transplant recipients hospitalized with HIV-infected patients

Molecular evidence of Pneumocystis transmission in pediatric transplant unit

Anti-cancer activity of 5-O-alkyl 1,4-imino-1,4-dideoxyribitols

Sulfa resistance and dihydropteroate synthase mutants in recurrent Pneumocystis carinii pneumonia

Synthesis and structure-activity relationship of new nicotinamide phosphoribosyltransferase inhibitors with antitumor activity on solid and haematological cancer

Experimental Drainage Device to Reduce Lymphoedema in a Rat Model

Identification of new FK866 analogues with potent anticancer activity against pancreatic cancer

Genetic diversity of Pneumocystis carinii in HIV-positive and -negative patients as revealed by PCR-SSCP typing

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