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Spectrum and Degree of CDK Drug Interactions Predicts Clinical Performance

Molecular cancer therapeutics, 2016-10, Vol.15 (10), p.2273-2281

2016

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Covalent EGFR inhibitor analysis reveals importance of reversible interactions to potency and mechanisms of drug resistance

Proceedings of the National Academy of Sciences - PNAS, 2014-01, Vol.111 (1), p.173-178

2014

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Small molecule inhibitors reveal PTK6 kinase is not an oncogenic driver in breast cancers

PloS one, 2018-06, Vol.13 (6), p.e0198374-e0198374

2018

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Discovery of Aryloxy Tetramethylcyclobutanes as Novel Androgen Receptor Antagonists

Journal of medicinal chemistry, 2011-11, Vol.54 (21), p.7693-7704

2011

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Discovery of 3-aryloxy-lactam analogs as potent androgen receptor full antagonists for treating castration resistant prostate cancer

Bioorganic & medicinal chemistry letters, 2012-01, Vol.22 (2), p.1230-1236

2012

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Critical Assessment of State‐of‐the‐Art Ligand‐Based Virtual Screening Methods

Molecular informatics, 2022-11, Vol.41 (11), p.e2200103-n/a

2022

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An allosteric cyclin E-CDK2 site mapped by paralog hopping with covalent probes

Nature chemical biology, 2024-09

2024

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Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer

Journal of medicinal chemistry, 2021-07, Vol.64 (13), p.9056-9077

2021

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Protein redox chemistry: post-translational cysteine modifications that regulate signal transduction and drug pharmacology

Frontiers in pharmacology, 2014-10, Vol.5, p.224-224

2014

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Discovery of Allosteric, Potent, Subtype Selective, and Peripherally Restricted TrkA Kinase Inhibitors

Journal of medicinal chemistry, 2019-01, Vol.62 (1), p.247-265

2019

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Discovery of N‑((3R,4R)‑4-Fluoro-1-(6-((3-methoxy-1-methyl‑1H‑pyrazol-4-yl)amino)-9-methyl‑9H‑purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR

Journal of medicinal chemistry, 2017-04, Vol.60 (7), p.3002-3019

2017

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The First Palladium(0) Complex of a Linear 1,6,11-Triyne. A Reactive Intermediate in the Catalytic Cyclotrimerization of a Triyne

Organometallics, 2000-06, Vol.19 (13), p.2403-2405

2000

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Discovery of Allosteric, Potent, Subtype Selective, and Peripherally Restricted TrkA Kinase Inhibitors

Journal of medicinal chemistry, 2018-04, Vol.62 (1)

2018

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Design of oxobenzimidazoles and oxindoles as novel androgen receptor antagonists

Bioorganic & medicinal chemistry letters, 2012-04, Vol.22 (7), p.2572-2578

2012

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Palladium(0)-Catalyzed Intramolecular [2+2+2] Alkyne Cyclotrimerizations with Electron-Deficient Diynes and Triynes

Chemistry : a European journal, 2003-06, Vol.9 (11), p.2469-2483

2003

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Discovery of N -((3 R ,4 R )-4-Fluoro-1-(6-((3-methoxy-1-methyl-1 H -pyrazol-4-yl)amino)-9-methyl-9 H -purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR

Journal of medicinal chemistry, 2017-04, Vol.60 (7), p.3002-3019

2017

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Pd(0)-catalyzed selective [2 + 2 + 2] cycloaddition of dimethyl nona-2,7-diyne-1,9-dioate derivatives with dimethyl acetylenedicarboxylate

Tetrahedron letters, 1999-07, Vol.40 (27), p.5035-5038

1999

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Congenital epulis--an electron microscopic observations of two cases

Kurume medical journal, 1990, Vol.37 (4), p.293-299

1990

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Clinico-pathological examination in lipoma and lipoma like lesion

Nihon Koku Geka Gakkai zasshi, 1990, Vol.36 (4), p.1066-1075

1990

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A case of peripheral ameloblastoma arising in the maxilla

Nihon Koku Geka Gakkai zasshi, 1992, Vol.38 (9), p.1437-1438

1992

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Effects of Intermittent Wakening on Sleep Pattern of Nighttime Caregiver: An EEG Study with a Single Subject

Nihon Kango Kagakki shi, 1997, Vol.17 (1), p.75-81

1997

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Effects of intermittent wakening on sleep pattern of nighttime caregiver: an EEG study with a single subject

Nihon Kango Kagakki shi, 1997-02, Vol.17 (1), p.75

1997

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ChemInform Abstract: Pd(0)-Catalyzed Selective [2 + 2 + 2] Cycloaddition of Dimethyl Nona-2,7-diyne-1,9-dioate Derivatives with Dimethyl Acetylenedicarboxylate

ChemInform, 1999-09, Vol.30 (39), p.no-no

1999

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Practical Cooperation and Collaboration between Community-based Care Hospital Nurses and Home-Visiting Nurses to Support Elderly People with Dementia Returning Home

Yamaguchi igaku, 2023-09, Vol.72 (3), p.97

2023

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Practical Cooperation and Collaboration between Community-based Care Hospital Nurses and Home-Visiting Nurses to Support Elderly People with Dementia Returning Home

Yamaguchi Medical Journal, 2023/09/01, Vol.72(3), pp.97

2023

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Spectrum and Degree of CDK Drug Interactions Predicts Clinical Performance

Covalent EGFR inhibitor analysis reveals importance of reversible interactions to potency and mechanisms of drug resistance

Small molecule inhibitors reveal PTK6 kinase is not an oncogenic driver in breast cancers

Discovery of Aryloxy Tetramethylcyclobutanes as Novel Androgen Receptor Antagonists

Discovery of 3-aryloxy-lactam analogs as potent androgen receptor full antagonists for treating castration resistant prostate cancer

Critical Assessment of State‐of‐the‐Art Ligand‐Based Virtual Screening Methods

An allosteric cyclin E-CDK2 site mapped by paralog hopping with covalent probes

Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer

Protein redox chemistry: post-translational cysteine modifications that regulate signal transduction and drug pharmacology

Discovery of Allosteric, Potent, Subtype Selective, and Peripherally Restricted TrkA Kinase Inhibitors

The First Palladium(0) Complex of a Linear 1,6,11-Triyne. A Reactive Intermediate in the Catalytic Cyclotrimerization of a Triyne

Discovery of Allosteric, Potent, Subtype Selective, and Peripherally Restricted TrkA Kinase Inhibitors

Design of oxobenzimidazoles and oxindoles as novel androgen receptor antagonists

Palladium(0)-Catalyzed Intramolecular [2+2+2] Alkyne Cyclotrimerizations with Electron-Deficient Diynes and Triynes

Pd(0)-catalyzed selective [2 + 2 + 2] cycloaddition of dimethyl nona-2,7-diyne-1,9-dioate derivatives with dimethyl acetylenedicarboxylate

Congenital epulis--an electron microscopic observations of two cases

Clinico-pathological examination in lipoma and lipoma like lesion

A case of peripheral ameloblastoma arising in the maxilla

Effects of Intermittent Wakening on Sleep Pattern of Nighttime Caregiver: An EEG Study with a Single Subject

Effects of intermittent wakening on sleep pattern of nighttime caregiver: an EEG study with a single subject

ChemInform Abstract: Pd(0)-Catalyzed Selective [2 + 2 + 2] Cycloaddition of Dimethyl Nona-2,7-diyne-1,9-dioate Derivatives with Dimethyl Acetylenedicarboxylate

Practical Cooperation and Collaboration between Community-based Care Hospital Nurses and Home-Visiting Nurses to Support Elderly People with Dementia Returning Home

Practical Cooperation and Collaboration between Community-based Care Hospital Nurses and Home-Visiting Nurses to Support Elderly People with Dementia Returning Home

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