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Localizing matrix metalloproteinase activities in the pericellular environment

The FEBS journal, 2011-01, Vol.278 (1), p.2-15

2011

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Interleukin‐1 Acts via the JNK‐2 Signaling Pathway to Induce Aggrecan Degradation by Human Chondrocytes

Arthritis & rheumatology (Hoboken, N.J.), 2015-07, Vol.67 (7), p.1826-1836

2015

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TIMP-3 facilitates binding of target metalloproteinases to the endocytic receptor LRP-1 and promotes scavenging of MMP-1

Scientific reports, 2020-07, Vol.10 (1), p.12067-12067, Article 12067

2020

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Tissue inhibitor of metalloproteinases (TIMP)‐1 creates a premetastatic niche in the liver through SDF‐1/CXCR4‐dependent neutrophil recruitment in mice

Hepatology (Baltimore, Md.), 2015-01, Vol.61 (1), p.238-248

2015

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LRP1 Controls TNF Release via the TIMP-3/ADAM17 Axis in Endotoxin-Activated Macrophages

The Journal of immunology (1950), 2019-03, Vol.202 (5), p.1501-1509

2019

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Structural insights into triple-helical collagen cleavage by matrix metalloproteinase 1

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (31), p.12461-12466

2012

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The tissue inhibitors of metalloproteinases (TIMPs): An ancient family with structural and functional diversity

Biochimica et biophysica acta, 2010, Vol.1803 (1), p.55-71

2010

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Tissue inhibitors of metalloproteinases: evolution, structure and function

Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular Enzymology, 2000-03, Vol.1477 (1), p.267-283

2000

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Proteases involved in cartilage matrix degradation in osteoarthritis

Biochimica et biophysica acta, 2012-01, Vol.1824 (1), p.133-145

2012

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Antibody-based exosite inhibitors of ADAMTS-5 (aggrecanase-2)

Biochemical journal, 2015-11, Vol.471 (3), p.391-401

2015

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In Vivo Imaging of MMP‐13 Activity Using a Specific Polymer‐FRET Peptide Conjugate Detects Early Osteoarthritis and Inhibitor Efficacy

Advanced functional materials, 2018-09, Vol.28 (37), p.n/a

2018

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The MET/Vascular Endothelial Growth Factor Receptor (VEGFR)-targeted Tyrosine Kinase Inhibitor Also Attenuates FMS-dependent Osteoclast Differentiation and Bone Destruction Induced by Prostate Cancer

The Journal of biological chemistry, 2016-09, Vol.291 (40), p.20891-20899

2016

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Differential Regulation of Extracellular Tissue Inhibitor of Metalloproteinases-3 Levels by Cell Membrane-bound and Shed Low Density Lipoprotein Receptor-related Protein 1

The Journal of biological chemistry, 2013-01, Vol.288 (1), p.332-342

2013

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TIMP-3 Is a Potent Inhibitor of Aggrecanase 1 (ADAM-TS4) and Aggrecanase 2 (ADAM-TS5)

The Journal of biological chemistry, 2001-04, Vol.276 (16), p.12501-12504

2001

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The Second Dimer Interface of MT1-MMP, the Transmembrane Domain, Is Essential for ProMMP-2 Activation on the Cell Surface

The Journal of biological chemistry, 2008-05, Vol.283 (19), p.13053-13062

2008

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MMPs are less efficient than ADAMTS5 in cleaving aggrecan core protein

Matrix biology, 2011-03, Vol.30 (2), p.145-153

2011

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Dissecting the interaction between tissue inhibitor of metalloproteinases-3 (TIMP-3) and low density lipoprotein receptor-related protein-1 (LRP-1): Development of a “TRAP” to increase levels of TIMP-3 in the tissue

Matrix biology, 2017-05, Vol.59, p.69-79

2017

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Overexpression of TIMP-3 in Chondrocytes Produces Transient Reduction in Growth Plate Length but Permanently Reduces Adult Bone Quality and Quantity

PloS one, 2016-12, Vol.11 (12), p.e0167971-e0167971

2016

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Indoxyl sulfate, a uremic toxin in chronic kidney disease, suppresses both bone formation and bone resorption

FEBS open bio, 2017-08, Vol.7 (8), p.1178-1185

2017

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Carcinomas Contain a Matrix Metalloproteinase-Resistant Isoform of Type I Collagen Exerting Selective Support to Invasion

Cancer research (Chicago, Ill.), 2010-06, Vol.70 (11), p.4366-4374

2010

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Functional Differences of the Catalytic and Non-catalytic Domains in Human ADAMTS-4 and ADAMTS-5 in Aggrecanolytic Activity

The Journal of biological chemistry, 2008-03, Vol.283 (11), p.6706-6716

2008

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Dimerization of MT1-MMP during cellular invasion detected by fluorescence resonance energy transfer

Biochemical journal, 2011-12, Vol.440 (3), p.319-327

2011

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Abrogation of prostaglandin E-EP4 signaling in osteoblasts prevents the bone destruction induced by human prostate cancer metastases

Biochemical and biophysical research communications, 2016-09, Vol.478 (1), p.154-161

2016

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ADAM17-dependent proteolysis of L-selectin promotes early clonal expansion of cytotoxic T cells

Scientific reports, 2019-04, Vol.9 (1), p.5487-5487, Article 5487

2019

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Tissue inhibitor of metalloproteinases-3 induces apoptosis in melanoma cells by stabilization of death receptors

Oncogene, 2003-04, Vol.22 (14), p.2121-2134

2003

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Localizing matrix metalloproteinase activities in the pericellular environment

Interleukin‐1 Acts via the JNK‐2 Signaling Pathway to Induce Aggrecan Degradation by Human Chondrocytes

TIMP-3 facilitates binding of target metalloproteinases to the endocytic receptor LRP-1 and promotes scavenging of MMP-1

Tissue inhibitor of metalloproteinases (TIMP)‐1 creates a premetastatic niche in the liver through SDF‐1/CXCR4‐dependent neutrophil recruitment in mice

LRP1 Controls TNF Release via the TIMP-3/ADAM17 Axis in Endotoxin-Activated Macrophages

Structural insights into triple-helical collagen cleavage by matrix metalloproteinase 1

The tissue inhibitors of metalloproteinases (TIMPs): An ancient family with structural and functional diversity

Tissue inhibitors of metalloproteinases: evolution, structure and function

Proteases involved in cartilage matrix degradation in osteoarthritis

Antibody-based exosite inhibitors of ADAMTS-5 (aggrecanase-2)

In Vivo Imaging of MMP‐13 Activity Using a Specific Polymer‐FRET Peptide Conjugate Detects Early Osteoarthritis and Inhibitor Efficacy

The MET/Vascular Endothelial Growth Factor Receptor (VEGFR)-targeted Tyrosine Kinase Inhibitor Also Attenuates FMS-dependent Osteoclast Differentiation and Bone Destruction Induced by Prostate Cancer

Differential Regulation of Extracellular Tissue Inhibitor of Metalloproteinases-3 Levels by Cell Membrane-bound and Shed Low Density Lipoprotein Receptor-related Protein 1

TIMP-3 Is a Potent Inhibitor of Aggrecanase 1 (ADAM-TS4) and Aggrecanase 2 (ADAM-TS5)

The Second Dimer Interface of MT1-MMP, the Transmembrane Domain, Is Essential for ProMMP-2 Activation on the Cell Surface

MMPs are less efficient than ADAMTS5 in cleaving aggrecan core protein

Dissecting the interaction between tissue inhibitor of metalloproteinases-3 (TIMP-3) and low density lipoprotein receptor-related protein-1 (LRP-1): Development of a “TRAP” to increase levels of TIMP-3 in the tissue

Overexpression of TIMP-3 in Chondrocytes Produces Transient Reduction in Growth Plate Length but Permanently Reduces Adult Bone Quality and Quantity

Indoxyl sulfate, a uremic toxin in chronic kidney disease, suppresses both bone formation and bone resorption

Carcinomas Contain a Matrix Metalloproteinase-Resistant Isoform of Type I Collagen Exerting Selective Support to Invasion

Functional Differences of the Catalytic and Non-catalytic Domains in Human ADAMTS-4 and ADAMTS-5 in Aggrecanolytic Activity

Dimerization of MT1-MMP during cellular invasion detected by fluorescence resonance energy transfer

Abrogation of prostaglandin E-EP4 signaling in osteoblasts prevents the bone destruction induced by human prostate cancer metastases

ADAM17-dependent proteolysis of L-selectin promotes early clonal expansion of cytotoxic T cells

Tissue inhibitor of metalloproteinases-3 induces apoptosis in melanoma cells by stabilization of death receptors

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