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In-vitro mercaptopyruvate sulfurtransferase species comparison in humans and common laboratory animals

Toxicology letters, 2017-05, Vol.274, p.64-68

2017

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An Orally Bioavailable (Mice) Prodrug of Glutathione

Antioxidants, 2021-06, Vol.10 (6), p.939

2021

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Development of sulfanegen for mass cyanide casualties

Annals of the New York Academy of Sciences, 2016-06, Vol.1374 (1), p.202-209

2016

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Cyanide Antidotes for Mass Casualties: Water-Soluble Salts of the Dithiane (Sulfanegen) from 3‑Mercaptopyruvate for Intramuscular Administration

Journal of medicinal chemistry, 2013-02, Vol.56 (3), p.1346-1349

2013

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Cyanide Toxicity in Juvenile Pigs and Its Reversal by a New Prodrug, Sulfanegen Sodium

Anesthesia and analgesia, 2012-05, Vol.114 (5), p.956-961

2012

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Sulfanegen sodium treatment in a rabbit model of sub-lethal cyanide toxicity

Toxicology and applied pharmacology, 2010-11, Vol.248 (3), p.269-276

2010

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Novel, Orally Effective Cyanide Antidotes

Journal of medicinal chemistry, 2007-12, Vol.50 (26), p.6462-6464

2007

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Donors of HNO

Current topics in medicinal chemistry, 2005-01, Vol.5 (7), p.649

2005

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Reaction between S-Nitrosothiols and Thiols: Generation of Nitroxyl (HNO) and Subsequent Chemistry

Biochemistry (Easton), 1998-04, Vol.37 (16), p.5362-5371

1998

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The combination of cobinamide and sulfanegen is highly effective in mouse models of cyanide poisoning

Clinical toxicology (Philadelphia, Pa.), 2011-06, Vol.49 (5), p.366-373

2011

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Diverse antioxidants protect against acetaminophen hepatotoxicity

Journal of biochemical and molecular toxicology, 2005-01, Vol.18 (6), p.361-368

2005

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A novel paradigm for assessing efficacies of potential antidotes against neurotoxins in mice

Toxicology letters, 2007-12, Vol.175 (1), p.111-117

2007

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Prodrugs of nitroxyl as inhibitors of aldehyde dehydrogenase

Journal of medicinal chemistry, 1992-10, Vol.35 (20), p.3648-3652

1992

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Prodrugs of L-cysteine as protective agents against acetaminophen-induced hepatotoxicity. 2-(Polyhydroxyalkyl)- and 2-(polyacetoxyalkyl)thiazolidine-4(R)-carboxylic acids

Journal of medicinal chemistry, 1987-10, Vol.30 (10), p.1891-1896

1987

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Reaction of Nitric Oxide with the Free Sulfhydryl Group of Human Serum Albumin Yields a Sulfenic Acid and Nitrous Oxide

Biochemistry (Easton), 1995-09, Vol.34 (36), p.11494-11499

1995

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Glutathione monoethyl ester protects against glutathione deficiencies due to aging and acetaminophen in mice

Mechanisms of ageing and development, 2000-12, Vol.120 (1), p.127-139

2000

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2-Substituted thiazolidine-4(R)-carboxylic acids as prodrugs of L-cysteine. Protection of mice against acetaminophen hepatotoxicity

Journal of medicinal chemistry, 1984-05, Vol.27 (5), p.591-596

1984

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Hepatoprotection by L-cysteine-glutathione mixed disulfide, a sulfhydryl-modified prodrug of glutathione

Journal of biochemical and molecular toxicology, 2003, Vol.17 (2), p.95-97

2003

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Carbethoxylating Agents as Inhibitors of Aldehyde Dehydrogenase

Journal of medicinal chemistry, 1995-05, Vol.38 (11), p.1872-1876

1995

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Acetaminophen-induced suppression of hepatic AdoMet synthetase activity is attenuated by prodrugs of l-cysteine

Toxicology letters, 2002-06, Vol.132 (1), p.1-8

2002

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p-Aminophenol-induced hepatotoxicity in hamsters: Role of glutathione

Journal of biochemical and molecular toxicology, 2004, Vol.18 (3), p.154-161

2004

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N-Terminal Dipeptides of d(−)-Penicillamine as Sequestration Agents for Acetaldehyde

Journal of medicinal chemistry, 2000-03, Vol.43 (5), p.1029-1033

2000

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Effects of 2( RS)- n-propylthiazolidine-4( R)-carboxylic acid on extrahepatic sulfhydryl levels in mice treated with acetaminophen

Biochemical pharmacology, 2001-04, Vol.61 (7), p.925-931

2001

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Diethylcarbamoylating/Nitroxylating Agents as Dual Action Inhibitors of Aldehyde Dehydrogenase: A Disulfiram−Cyanamide Merger

Journal of medicinal chemistry, 1999-10, Vol.42 (20), p.4016-4020

1999

Volltextzugriff (PDF)

Prodrugs of Nitroxyl and Nitrosobenzene as Cascade Latentiated Inhibitors of Aldehyde Dehydrogenase

Journal of medicinal chemistry, 1998-07, Vol.41 (15), p.2903-2909

1998

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In-vitro mercaptopyruvate sulfurtransferase species comparison in humans and common laboratory animals

An Orally Bioavailable (Mice) Prodrug of Glutathione

Development of sulfanegen for mass cyanide casualties

Cyanide Antidotes for Mass Casualties: Water-Soluble Salts of the Dithiane (Sulfanegen) from 3‑Mercaptopyruvate for Intramuscular Administration

Cyanide Toxicity in Juvenile Pigs and Its Reversal by a New Prodrug, Sulfanegen Sodium

Sulfanegen sodium treatment in a rabbit model of sub-lethal cyanide toxicity

Novel, Orally Effective Cyanide Antidotes

Donors of HNO

Reaction between S-Nitrosothiols and Thiols: Generation of Nitroxyl (HNO) and Subsequent Chemistry

The combination of cobinamide and sulfanegen is highly effective in mouse models of cyanide poisoning

Diverse antioxidants protect against acetaminophen hepatotoxicity

A novel paradigm for assessing efficacies of potential antidotes against neurotoxins in mice

Prodrugs of nitroxyl as inhibitors of aldehyde dehydrogenase

Prodrugs of L-cysteine as protective agents against acetaminophen-induced hepatotoxicity. 2-(Polyhydroxyalkyl)- and 2-(polyacetoxyalkyl)thiazolidine-4(R)-carboxylic acids

Reaction of Nitric Oxide with the Free Sulfhydryl Group of Human Serum Albumin Yields a Sulfenic Acid and Nitrous Oxide

Glutathione monoethyl ester protects against glutathione deficiencies due to aging and acetaminophen in mice

2-Substituted thiazolidine-4(R)-carboxylic acids as prodrugs of L-cysteine. Protection of mice against acetaminophen hepatotoxicity

Hepatoprotection by L-cysteine-glutathione mixed disulfide, a sulfhydryl-modified prodrug of glutathione

Carbethoxylating Agents as Inhibitors of Aldehyde Dehydrogenase

Acetaminophen-induced suppression of hepatic AdoMet synthetase activity is attenuated by prodrugs of l-cysteine

p-Aminophenol-induced hepatotoxicity in hamsters: Role of glutathione

N-Terminal Dipeptides of d(−)-Penicillamine as Sequestration Agents for Acetaldehyde

Effects of 2( RS)- n-propylthiazolidine-4( R)-carboxylic acid on extrahepatic sulfhydryl levels in mice treated with acetaminophen

Diethylcarbamoylating/Nitroxylating Agents as Dual Action Inhibitors of Aldehyde Dehydrogenase: A Disulfiram−Cyanamide Merger

Prodrugs of Nitroxyl and Nitrosobenzene as Cascade Latentiated Inhibitors of Aldehyde Dehydrogenase

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