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Synthesis of a novel duocarmycin derivative DU-257 and its application to immunoconjugate using poly(ethylene glycol)-dipeptidyl linker capable of tumor specific activation

Bioorganic & medicinal chemistry, 2000-08, Vol.8 (8), p.2175-2184

2000

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Studies on the active metabolite (DU-86) of KW-2189, a novel derivative of duocarmycin

Bioorganic & medicinal chemistry letters, 1996-09, Vol.6 (17), p.2147-2150

1996

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Synthesis and Antitumor Activity of Duocarmycin Derivatives : A-Ring Pyrrole Compounds Bearing 5-Membered Heteroarylacryloyl Groups

Chemical and Pharmaceutical Bulletin, 1999/10/15, Vol.47(10), pp.1393-1403

1999

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Synthesis and Antitumor Activity of Duocarmycin Derivatives : Modification of Segment A of Duocarmycin B2

Chemical and Pharmaceutical Bulletin, 1996/09/15, Vol.44(9), pp.1723-1730

1996

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Synthesis and Antitumor Activity of Duocarmycin Derivatives

Chemical and Pharmaceutical Bulletin, 1995/09/15, Vol.43(9), pp.1530-1535

1995

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Wagner-Meerwein Rearrangement of Duocarmycins

Chemical and Pharmaceutical Bulletin, 1996/05/15, Vol.44(5), pp.933-939

1996

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Practical preparation of K-252a from a fermentation solution

Bioscience, biotechnology, and biochemistry, 1998, Vol.62 (8), p.1627-1629

1998

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A Novel Property of Duocarmycin and Its Analogs for Covalent Reaction with DNA

Journal of the American Chemical Society, 1994-05, Vol.116 (10), p.4171-4177

1994

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New Water-Soluble Duocarmycin Derivatives: Synthesis and Antitumor Activity of A-Ring Pyrrole Compounds Bearing β-Heteroarylacryloyl Groups

Journal of medicinal chemistry, 1999-02, Vol.42 (4), p.669-676

1999

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Synthesis and antitumor activity of duocarmycin derivatives: A-ring pyrrole analogues of duocarmycin B2

Bioorganic & medicinal chemistry, 1996-08, Vol.4 (8), p.1379-1391

1996

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Regiospecific sulfonation of secondary hydroxyl groups of .alpha.-cyclodextrin. Its application to preparation of 2A2B, 2A2C-, and 2A2D-disulfonates

Journal of the American Chemical Society, 1985-05, Vol.107 (11), p.3233-3235

1985

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Synthesis and HPLC analysis of enzymatically cleavable linker consisting of poly(ethylene glycol) and dipeptide for the development of immunoconjugate

Journal of controlled release, 2000-10, Vol.69 (1), p.27-41

2000

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Synthesis and antitumor activity of duocarmycin derivatives : A-ring pyrrole compounds bearing β-(5', 6', 7'-trimethoxy-2'-indolyl)acryloyl group

Bioorganic & medicinal chemistry, 2000-07, Vol.8 (7), p.1637-1643

2000

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Characteristics of antitumor activity of KW-2189, a novel water-soluble derivative of duocarmycin, against murine and human tumors

Cancer research (Chicago, Ill.), 1994-05, Vol.54 (9), p.2404

1994

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Antitumor antibiotics: Duocarmycins

Chemistry of heterocyclic compounds (New York, N.Y. 1965), 1998-12, Vol.34 (12), p.1386-1405

1998

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Synthesis and Antitumor Activity of Duocarmycin Derivatives: A-Ring Pyrrole Compounds Bearing Cinnamoyl Groups

Journal of medicinal chemistry, 1997-03, Vol.40 (6), p.972-979

1997

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Synthesis of specifically modified maltooligosaccharides by enzymic degradation of cyclodextrin derivatives. Substrate-based investigation of the active site of Taka-amylase

Journal of organic chemistry, 1987-02, Vol.52 (4), p.636-640

1987

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Synthesis and antitumor activity of novel duocarmycin derivatives

Bioorganic & medicinal chemistry letters, 1996-06, Vol.6 (11), p.1215-1220

1996

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Synthesis and antitumor activity of water-soluble duocarmycin B1 prodrugs

Bioorganic & medicinal chemistry letters, 1999-10, Vol.9 (20), p.2995-2998

1999

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Synthesis and antitumor activity of duocarmycin derivatives

Bioorganic & medicinal chemistry, 2000-07, Vol.8 (7), p.1637-1643

2000

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Synthesis and antitumor activity of duocarmycin derivatives : Modification at C-8 position of A-ring pyrrole compounds bearing the simplified DNA-binding groups

Bioorganic & medicinal chemistry, 2000-02, Vol.8 (2), p.381-391

2000

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Studies on duocarmycin SA and its derivatives

Bioorganic & medicinal chemistry, 1997-03, Vol.5 (3), p.623-630

1997

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The reversible DNA-alkylating activity of duocarmycin and its analogues

Nucleic acids research, 1994-01, Vol.22 (1), p.88-93

1994

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Synthesis and Antitumor Activity of Duocarmycin Derivatives

Chemical & pharmaceutical bulletin, 1999-10, Vol.47 (10), p.1393

1999

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Practical Synthesis of the High-Quality Antitumor Agent KW-2189 from Duocarmycin B2 Using a Facile One-Pot Synthesis of an Intermediate

Organic process research & development, 1998-11, Vol.2 (6), p.344-350

1998

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Synthesis of a novel duocarmycin derivative DU-257 and its application to immunoconjugate using poly(ethylene glycol)-dipeptidyl linker capable of tumor specific activation

Studies on the active metabolite (DU-86) of KW-2189, a novel derivative of duocarmycin

Synthesis and Antitumor Activity of Duocarmycin Derivatives : A-Ring Pyrrole Compounds Bearing 5-Membered Heteroarylacryloyl Groups

Synthesis and Antitumor Activity of Duocarmycin Derivatives : Modification of Segment A of Duocarmycin B2

Synthesis and Antitumor Activity of Duocarmycin Derivatives

Wagner-Meerwein Rearrangement of Duocarmycins

Practical preparation of K-252a from a fermentation solution

A Novel Property of Duocarmycin and Its Analogs for Covalent Reaction with DNA

New Water-Soluble Duocarmycin Derivatives: Synthesis and Antitumor Activity of A-Ring Pyrrole Compounds Bearing β-Heteroarylacryloyl Groups

Synthesis and antitumor activity of duocarmycin derivatives: A-ring pyrrole analogues of duocarmycin B2

Regiospecific sulfonation of secondary hydroxyl groups of .alpha.-cyclodextrin. Its application to preparation of 2A2B, 2A2C-, and 2A2D-disulfonates

Synthesis and HPLC analysis of enzymatically cleavable linker consisting of poly(ethylene glycol) and dipeptide for the development of immunoconjugate

Synthesis and antitumor activity of duocarmycin derivatives : A-ring pyrrole compounds bearing β-(5', 6', 7'-trimethoxy-2'-indolyl)acryloyl group

Characteristics of antitumor activity of KW-2189, a novel water-soluble derivative of duocarmycin, against murine and human tumors

Antitumor antibiotics: Duocarmycins

Synthesis and Antitumor Activity of Duocarmycin Derivatives: A-Ring Pyrrole Compounds Bearing Cinnamoyl Groups

Synthesis of specifically modified maltooligosaccharides by enzymic degradation of cyclodextrin derivatives. Substrate-based investigation of the active site of Taka-amylase

Synthesis and antitumor activity of novel duocarmycin derivatives

Synthesis and antitumor activity of water-soluble duocarmycin B1 prodrugs

Synthesis and antitumor activity of duocarmycin derivatives

Synthesis and antitumor activity of duocarmycin derivatives : Modification at C-8 position of A-ring pyrrole compounds bearing the simplified DNA-binding groups

Studies on duocarmycin SA and its derivatives

The reversible DNA-alkylating activity of duocarmycin and its analogues

Synthesis and Antitumor Activity of Duocarmycin Derivatives

Practical Synthesis of the High-Quality Antitumor Agent KW-2189 from Duocarmycin B2 Using a Facile One-Pot Synthesis of an Intermediate

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