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Chronic Behavioral Manipulation via Orally Delivered Chemogenetic Actuator in Macaques

The Journal of neuroscience, 2022-03, Vol.42 (12), p.2552-2561

2022

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A Series of Dibenzofuran‐Based n‐Type Exciplex Host Partners Realizing High‐Efficiency and Stable Deep‐Red Phosphorescent OLEDs

Chemistry : a European journal, 2019-05, Vol.25 (30), p.7308-7314

2019

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Single caudate neurons encode temporally discounted value for formulating motivation for action

eLife, 2021-07, Vol.10

2021

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Highly efficient, deep-red organic light-emitting devices using energy transfer from exciplexes

Journal of materials chemistry. C, Materials for optical and electronic devices, 2017, Vol.5 (3), p.527-530

2017

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D1- and D2-like receptors differentially mediate the effects of dopaminergic transmission on cost–benefit evaluation and motivation in monkeys

PLoS biology, 2021-07, Vol.19 (7), p.e3001055-e3001055

2021

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Macaques Exhibit Implicit Gaze Bias Anticipating Others’ False-Belief-Driven Actions via Medial Prefrontal Cortex

Cell reports (Cambridge), 2020-03, Vol.30 (13), p.4433-4444.e5

2020

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[11C]deschloroclozapine is an improved PET radioligand for quantifying a human muscarinic DREADD expressed in monkey brain

Journal of cerebral blood flow and metabolism, 2021-10, Vol.41 (10), p.2571-2582

2021

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DOCK–PET: database of CNS kinetic parameters in the healthy human brain for existing PET tracers

Annals of nuclear medicine, 2024-08, Vol.38 (8), p.666-672

2024

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PET imaging of colony-stimulating factor 1 receptor: A head-to-head comparison of a novel radioligand, 11C-GW2580, and 11C-CPPC, in mouse models of acute and chronic neuroinflammation and a rhesus monkey

Journal of cerebral blood flow and metabolism, 2021-09, Vol.41 (9), p.2410-2422

2021

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A genetically targeted reporter for PET imaging of deep neuronal circuits in mammalian brains

The EMBO journal, 2021-11, Vol.40 (22), p.e107757-n/a

2021

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Synthesis and preclinical evaluation of [11C]MTP38 as a novel PET ligand for phosphodiesterase 7 in the brain

European journal of nuclear medicine and molecular imaging, 2021-09, Vol.48 (10), p.3101-3112

2021

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Multiscale chemogenetic dissection of fronto-temporal top-down regulation for object memory in primates

Nature communications, 2024-07, Vol.15 (1), p.5369-17, Article 5369

2024

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Chemogenetic sensory fMRI reveals behaviorally relevant bidirectional changes in primate somatosensory network

Neuron (Cambridge, Mass.), 2021-10, Vol.109 (20), p.3312-3322.e5

2021

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Reduced serotonergic transmission alters sensitivity to cost and reward via 5-HT1A and 5-HT1B receptors in monkeys

PLoS biology, 2024-01, Vol.22 (1), p.e3002445-e3002445

2024

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High Power Efficiency Blue‐to‐Green Organic Light‐Emitting Diodes Using Isonicotinonitrile‐Based Fluorescent Emitters

Chemistry, an Asian journal, 2017-03, Vol.12 (6), p.648-654

2017

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Signaling Incentive and Drive in the Primate Ventral Pallidum for Motivational Control of Goal-Directed Action

The Journal of neuroscience, 2019-03, Vol.39 (10), p.1793-1804

2019

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Design, Synthesis, and Evaluation of (4R)‑1-{3-[2‑(18F)Fluoro-4-methylpyridin-3-yl]phenyl}-4-[4-(1,3-thiazol-2-ylcarbonyl)piperazin-1-yl]pyrrolidin-2-one ([18F]T‑401) as a Novel Positron-Emission Tomography Imaging Agent for Monoacylglycerol Lipase

Journal of medicinal chemistry, 2019-03, Vol.62 (5), p.2362-2375

2019

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A mosaic adeno-associated virus vector as a versatile tool that exhibits high levels of transgene expression and neuron specificity in primate brain

Nature communications, 2023-08, Vol.14 (1), p.4762-4762, Article 4762

2023

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Targeted Delivery of Chemogenetic Adeno-Associated Viral Vectors to Cortical Sulcus Regions in Macaque Monkeys by Handheld Injections

Bio-protocol, 2023-12, Vol.13 (23), p.e4897-e4897

2023

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Chemogenetic attenuation of cortical seizures in nonhuman primates

Nature communications, 2023-02, Vol.14 (1), p.971-971, Article 971

2023

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PET imaging-guided chemogenetic silencing reveals a critical role of primate rostromedial caudate in reward evaluation

Nature communications, 2016-12, Vol.7 (1), p.13605-13605, Article 13605

2016

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Chemogenetic Disconnection between the Orbitofrontal Cortex and the Rostromedial Caudate Nucleus Disrupts Motivational Control of Goal-Directed Action

The Journal of neuroscience, 2022-08, Vol.42 (32), p.6267-6275

2022

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11C-Labeling of acyclic retinoid peretinoin by rapid C-[11C]methylation to disclose novel brain permeability and central nervous system activities hidden in antitumor agent

Bioorganic & medicinal chemistry letters, 2023-04, Vol.85, p.129212-129212, Article 129212

2023

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Chronic Behavioral Manipulation via Orally Delivered Chemogenetic Actuator in Macaques

A Series of Dibenzofuran‐Based n‐Type Exciplex Host Partners Realizing High‐Efficiency and Stable Deep‐Red Phosphorescent OLEDs

Single caudate neurons encode temporally discounted value for formulating motivation for action

Highly efficient, deep-red organic light-emitting devices using energy transfer from exciplexes

D1- and D2-like receptors differentially mediate the effects of dopaminergic transmission on cost–benefit evaluation and motivation in monkeys

Macaques Exhibit Implicit Gaze Bias Anticipating Others’ False-Belief-Driven Actions via Medial Prefrontal Cortex

[11C]deschloroclozapine is an improved PET radioligand for quantifying a human muscarinic DREADD expressed in monkey brain

Visualization of AMPA receptors in living human brain with positron emission tomography

DOCK–PET: database of CNS kinetic parameters in the healthy human brain for existing PET tracers

PET imaging of colony-stimulating factor 1 receptor: A head-to-head comparison of a novel radioligand, 11C-GW2580, and 11C-CPPC, in mouse models of acute and chronic neuroinflammation and a rhesus monkey

A genetically targeted reporter for PET imaging of deep neuronal circuits in mammalian brains

Synthesis and preclinical evaluation of [11C]MTP38 as a novel PET ligand for phosphodiesterase 7 in the brain

Multiscale chemogenetic dissection of fronto-temporal top-down regulation for object memory in primates

Chemogenetic sensory fMRI reveals behaviorally relevant bidirectional changes in primate somatosensory network

Reduced serotonergic transmission alters sensitivity to cost and reward via 5-HT1A and 5-HT1B receptors in monkeys

High Power Efficiency Blue‐to‐Green Organic Light‐Emitting Diodes Using Isonicotinonitrile‐Based Fluorescent Emitters

Signaling Incentive and Drive in the Primate Ventral Pallidum for Motivational Control of Goal-Directed Action

Design, Synthesis, and Evaluation of (4R)‑1-{3-[2‑(18F)Fluoro-4-methylpyridin-3-yl]phenyl}-4-[4-(1,3-thiazol-2-ylcarbonyl)piperazin-1-yl]pyrrolidin-2-one ([18F]T‑401) as a Novel Positron-Emission Tomography Imaging Agent for Monoacylglycerol Lipase

A mosaic adeno-associated virus vector as a versatile tool that exhibits high levels of transgene expression and neuron specificity in primate brain

Targeted Delivery of Chemogenetic Adeno-Associated Viral Vectors to Cortical Sulcus Regions in Macaque Monkeys by Handheld Injections

Chemogenetic attenuation of cortical seizures in nonhuman primates

PET imaging-guided chemogenetic silencing reveals a critical role of primate rostromedial caudate in reward evaluation

Chemogenetic Disconnection between the Orbitofrontal Cortex and the Rostromedial Caudate Nucleus Disrupts Motivational Control of Goal-Directed Action

11C-Labeling of acyclic retinoid peretinoin by rapid C-[11C]methylation to disclose novel brain permeability and central nervous system activities hidden in antitumor agent

Multimodal analyses of a non-human primate model harboring mutant amyloid precursor protein transgenes driven by the human EF1α promoter

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