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A Dual-Acting Nitric Oxide Donor and Phosphodiesterase 5 Inhibitor Activates Autophagy in Primary Skin Fibroblasts

International journal of molecular sciences, 2022-06, Vol.23 (12), p.6860

2022

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Impact of office layout on communication in a science-driven business

R & D management, 2008-09, Vol.38 (4), p.372-391

2008

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Topical Wound Treatment with a Nitric Oxide-Releasing PDE5 Inhibitor Formulation Enhances Blood Perfusion and Promotes Healing in Mice

Pharmaceutics, 2022-10, Vol.14 (11), p.2358

2022

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Formulation and dermal delivery of a new active pharmaceutical ingredient in an in vitro wound model for the treatment of chronic ulcers

European journal of pharmaceutics and biopharmaceutics, 2024-09, Vol.202, p.114373, Article 114373

2024

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Novartis School Lab: bringing young people closer to the world of research and discovering the excitement of science

Chimia, 2012-01, Vol.66 (11), p.832

2012

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A Dual-Acting Nitric Oxide Donor and Phosphodiesterase 5 Inhibitor Promotes Wound Healing in Normal Mice and Mice with Diabetes

Journal of investigative dermatology, 2021-02, Vol.141 (2), p.415-426

2021

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Bifunctional Sildenafil Diazeniumdiolates Acting as Phosphodiesterase 5 Inhibitors and Nitric Oxide Donors− Towards Wound Healing

Chembiochem : a European journal of chemical biology, 2024-04, Vol.25 (8), p.e202300801-n/a

2024

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Promotion of science among youngsters: today's crucial mission for tomorrow's society

Chimia, 2012-01, Vol.66 (11), p.817

2012

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Potent and selective xanthine-based inhibitors of phosphodiesterase 5

Bioorganic & medicinal chemistry letters, 2007-04, Vol.17 (8), p.2376-2379

2007

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Dual‐Mode Vasodilator M119 Delivery to Hair Follicle via Dissolving Microneedle for Advanced Alopecia Treatment

Advanced therapeutics, 2022-08, Vol.5 (8), p.n/a

2022

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N-(Triisopropylsilyl)pyrrole. A progenitor "par excellence" of 3-substituted pyrroles

Journal of organic chemistry, 1990-12, Vol.55 (26), p.6317-6328

1990

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Dual‐Mode Vasodilator M119 Delivery to Hair Follicle via Dissolving Microneedle for Advanced Alopecia Treatment (Adv. Therap. 8/2022)

Advanced therapeutics, 2022-08, Vol.5 (8), p.n/a

2022

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Alkylation of amino acids without loss of the optical activity: preparation of .alpha.-substituted proline derivatives. A case of self-reproduction of chirality

Journal of the American Chemical Society, 1983-08, Vol.105 (16), p.5390-5398

1983

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Enantioselective conjugate addition of rationally designed chiral cuprate reagents to 2-cycloalkenones

Journal of the American Chemical Society, 1986-10, Vol.108 (22), p.7114-7116

1986

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Herstellung enantiomerenreiner cis- oder trans-konfigurierter 2-(tert-Butyl)-3-methylimidazolidin-4-one aus den Aminosäuren (S)-Alanin, (S)-Phenylalanin, (R)-Phenylglycin, (S)-Methionin und (S)-Valin

Helvetica chimica acta, 1985-02, Vol.68 (1), p.135-143

1985

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3-Lithiopyrroles by Halogen-Metal Interchange of 3-Bromo-1-(triissopropylsilyl)pyrroles. Synthesis of Verucarin E and Other 3-Substituted Pyrroles. Preliminary Communication

Helvetica chimica acta, 1984-06, Vol.67 (4), p.1168-1172

1984

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Direct Diastereoselective Alkylation of Tartaric Acid Through an Enolate

Angewandte Chemie (International ed.), 1981-12, Vol.20 (12), p.1030-1031

1981

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New 1-amino-1,2-diphenylethanols as ligands for the enantioselective addition of alkyllithiums to benzaldehyde

Tetrahedron: asymmetry, 1999-01, Vol.10 (1), p.169-176

1999

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Stereoselektive Alkylierung an C(α) von Serin, Glycerinsäure, Threonin und Weinsäure über heterocyclische Enolate mit exocyclischer Doppelbindung

Helvetica chimica acta, 1987-07, Vol.70 (4), p.1194-1216

1987

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Herstellung enantiomerenreiner cis‐ oder trans‐konfigurierter 2‐(tert‐Butyl)‐3‐methylimidazolidin‐4‐one aus den Aminosäuren (S)‐Alanin, (S)‐Phenylalanin, (R)‐Phenylglycin, (S)‐Methionin und (S)‐Valin

Helvetica chimica acta, 1985-02, Vol.68 (1), p.135-143

1985

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8-Aryl xanthines potent inhibitors of phosphodiesterase 5

Bioorganic & medicinal chemistry letters, 2002-09, Vol.12 (18), p.2587-2590

2002

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Quinazolines: Combined type 3 and 4 phosphodiesterase inhibitors

Bioorganic & medicinal chemistry letters, 1998-10, Vol.8 (20), p.2891-2896

1998

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α-Alkylation of α-heterosubstituted carboxylic acids without racemization : EPC-syntheses of tertiary alcohols and thiols

Tetrahedron, 1984, Vol.40 (8), p.1313-1324

1984

Volltextzugriff (PDF)

Synthesis and Determination of the Absolute Configuration of (+)-Delesserine, a Metabolite of the Red Marine Alga Delesseria sanguinea (Lamouroux)

Angewandte Chemie (International ed.), 1984-07, Vol.23 (7), p.530-531

1984

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Stereoselektive Alkylierung an C(α) von Serin, Glycerinsäure, Threonin und Weinsäure über heterocyclische Enolate mit exocyclischer Doppelbindung

Helvetica chimica acta, 1987-07, Vol.70 (4), p.1194-1216

1987

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A Dual-Acting Nitric Oxide Donor and Phosphodiesterase 5 Inhibitor Activates Autophagy in Primary Skin Fibroblasts

Impact of office layout on communication in a science-driven business

Topical Wound Treatment with a Nitric Oxide-Releasing PDE5 Inhibitor Formulation Enhances Blood Perfusion and Promotes Healing in Mice

Formulation and dermal delivery of a new active pharmaceutical ingredient in an in vitro wound model for the treatment of chronic ulcers

Novartis School Lab: bringing young people closer to the world of research and discovering the excitement of science

A Dual-Acting Nitric Oxide Donor and Phosphodiesterase 5 Inhibitor Promotes Wound Healing in Normal Mice and Mice with Diabetes

Bifunctional Sildenafil Diazeniumdiolates Acting as Phosphodiesterase 5 Inhibitors and Nitric Oxide Donors− Towards Wound Healing

Promotion of science among youngsters: today's crucial mission for tomorrow's society

Potent and selective xanthine-based inhibitors of phosphodiesterase 5

Dual‐Mode Vasodilator M119 Delivery to Hair Follicle via Dissolving Microneedle for Advanced Alopecia Treatment

N-(Triisopropylsilyl)pyrrole. A progenitor "par excellence" of 3-substituted pyrroles

Dual‐Mode Vasodilator M119 Delivery to Hair Follicle via Dissolving Microneedle for Advanced Alopecia Treatment (Adv. Therap. 8/2022)

Alkylation of amino acids without loss of the optical activity: preparation of .alpha.-substituted proline derivatives. A case of self-reproduction of chirality

Enantioselective conjugate addition of rationally designed chiral cuprate reagents to 2-cycloalkenones

Herstellung enantiomerenreiner cis- oder trans-konfigurierter 2-(tert-Butyl)-3-methylimidazolidin-4-one aus den Aminosäuren (S)-Alanin, (S)-Phenylalanin, (R)-Phenylglycin, (S)-Methionin und (S)-Valin

3-Lithiopyrroles by Halogen-Metal Interchange of 3-Bromo-1-(triissopropylsilyl)pyrroles. Synthesis of Verucarin E and Other 3-Substituted Pyrroles. Preliminary Communication

Direct Diastereoselective Alkylation of Tartaric Acid Through an Enolate

New 1-amino-1,2-diphenylethanols as ligands for the enantioselective addition of alkyllithiums to benzaldehyde

Stereoselektive Alkylierung an C(α) von Serin, Glycerinsäure, Threonin und Weinsäure über heterocyclische Enolate mit exocyclischer Doppelbindung

Herstellung enantiomerenreiner cis‐ oder trans‐konfigurierter 2‐(tert‐Butyl)‐3‐methylimidazolidin‐4‐one aus den Aminosäuren (S)‐Alanin, (S)‐Phenylalanin, (R)‐Phenylglycin, (S)‐Methionin und (S)‐Valin

8-Aryl xanthines potent inhibitors of phosphodiesterase 5

Quinazolines: Combined type 3 and 4 phosphodiesterase inhibitors

α-Alkylation of α-heterosubstituted carboxylic acids without racemization : EPC-syntheses of tertiary alcohols and thiols

Synthesis and Determination of the Absolute Configuration of (+)-Delesserine, a Metabolite of the Red Marine Alga Delesseria sanguinea (Lamouroux)

Stereoselektive Alkylierung an C(α) von Serin, Glycerinsäure, Threonin und Weinsäure über heterocyclische Enolate mit exocyclischer Doppelbindung

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