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Targeting HIV Reservoir in Infected CD4 T Cells by Dual-Affinity Re-targeting Molecules (DARTs) that Bind HIV Envelope and Recruit Cytotoxic T Cells

PLoS pathogens, 2015-11, Vol.11 (11), p.e1005233-e1005233

2015

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Role of Fcγ receptors in HER2-targeted breast cancer therapy

Journal for immunotherapy of cancer, 2022-01, Vol.10 (1), p.e003171

2022

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MGD011, A CD19 x CD3 Dual-Affinity Retargeting Bi-specific Molecule Incorporating Extended Circulating Half-life for the Treatment of B-Cell Malignancies

Clinical cancer research, 2017-03, Vol.23 (6), p.1506-1518

2017

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Bispecific antibody-derived molecules to target persistent HIV infection

Journal of Virus Eradication, 2022-09, Vol.8 (3), p.100083-100083, Article 100083

2022

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Elimination of SHIV Infected Cells by Combinations of Bispecific HIVxCD3 DART ® Molecules

Frontiers in immunology, 2021-08, Vol.12, p.710273-710273

2021

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Redirection of Cord Blood T Cells and Natural Killer Cells for Elimination of Autologous HIV-1-Infected Target Cells Using Bispecific DART® Molecules

Frontiers in immunology, 2020-04, Vol.11, p.713-713

2020

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Humanized Monoclonal Antibody against West Nile Virus Envelope Protein Administered after Neuronal Infection Protects against Lethal Encephalitis in Hamsters

The Journal of infectious diseases, 2006-11, Vol.194 (9), p.1300-1308

2006

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Safety and Pharmacokinetics of Single Intravenous Dose of MGAWN1, a Novel Monoclonal Antibody to West Nile Virus

Antimicrobial Agents and Chemotherapy, 2010-06, Vol.54 (6), p.2431-2436

2010

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Vorinostat Renders the Replication-Competent Latent Reservoir of Human Immunodeficiency Virus (HIV) Vulnerable to Clearance by CD8 T Cells

EBioMedicine, 2017-09, Vol.23 (C), p.52-58

2017

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Envelope-specific antibodies and antibody-derived molecules for treating and curing HIV infection

Nature reviews. Drug discovery, 2016-12, Vol.15 (12), p.823-834

2016

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Correlation Between TIGIT Expression on CD8+ T Cells and Higher Cytotoxic Capacity

The Journal of infectious diseases, 2021-11, Vol.224 (9), p.1599-1604

2021

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Anti-tumor activity and toxicokinetics analysis of MGAH22, an anti-HER2 monoclonal antibody with enhanced Fcγ receptor binding properties

Breast cancer research : BCR, 2011-01, Vol.13 (6), p.R123-R123, Article R123

2011

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SMAC Mimetic Plus Triple-Combination Bispecific HIVxCD3 Retargeting Molecules in SHIV.C.CH505-Infected, Antiretroviral Therapy-Suppressed Rhesus Macaques

Journal of virology, 2020-10, Vol.94 (21)

2020

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Dual-Affinity Re-Targeting proteins direct T cell-mediated cytolysis of latently HIV-infected cells

The Journal of clinical investigation, 2015-11, Vol.125 (11), p.4077-4090

2015

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Defining Limits of Treatment with Humanized Neutralizing Monoclonal Antibody for West Nile Virus Neurological Infection in a Hamster Model

Antimicrobial Agents and Chemotherapy, 2007-07, Vol.51 (7), p.2396-2402

2007

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Margetuximab in HER2-positive metastatic breast cancer

Future oncology (London, England), 2023-05, Vol.19 (16), p.1099-1112

2023

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CD19xCD3 DART protein mediates human B-cell depletion in vivo in humanized BLT mice

Molecular therapy. Oncolytics, 2016, Vol.3 (C), p.15024-15024, Article 15024

2016

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Cationic Lipids Enhance Cytokine and Cell Influx Levels in the Lung Following Administration of Plasmid: Cationic Lipid Complexes

The Journal of immunology (1950), 1998-05, Vol.160 (9), p.4580-4586

1998

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The antiprogestin-dependent GeneSwitch ® system for regulated gene therapy

Steroids, 2003-11, Vol.68 (10), p.1085-1094

Nordstrom, Jeffrey L.

2003

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West Nile virus-induced acute flaccid paralysis is prevented by monoclonal antibody treatment when administered after infection of spinal cord neurons

Journal of neurovirology, 2008-04, Vol.14 (2), p.152-163

2008

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Antiprogestin-controllable transgene regulation in vivo

Current Opinion in Biotechnology, 2002-10, Vol.13 (5), p.453-458

Nordstrom, Jeffrey L

2002

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Ligand-Dependent Regulation of Vascular Endothelial Growth Factor and Erythropoietin Expression by a Plasmid-Based Autoinducible GeneSwitch System

Molecular therapy, 2000-09, Vol.2 (3), p.276-287

2000

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Enhanced animal growth via ligand-regulated GHRH myogenic-injectable vectors

The FASEB journal, 2002-03, Vol.16 (3), p.426-428

2002

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Targeting HIV Reservoir in Infected CD4 T Cells by Dual-Affinity Re-targeting Molecules (DARTs) that Bind HIV Envelope and Recruit Cytotoxic T Cells

Role of Fcγ receptors in HER2-targeted breast cancer therapy

MGD011, A CD19 x CD3 Dual-Affinity Retargeting Bi-specific Molecule Incorporating Extended Circulating Half-life for the Treatment of B-Cell Malignancies

Bispecific antibody-derived molecules to target persistent HIV infection

Elimination of SHIV Infected Cells by Combinations of Bispecific HIVxCD3 DART ® Molecules

Redirection of Cord Blood T Cells and Natural Killer Cells for Elimination of Autologous HIV-1-Infected Target Cells Using Bispecific DART® Molecules

Humanized Monoclonal Antibody against West Nile Virus Envelope Protein Administered after Neuronal Infection Protects against Lethal Encephalitis in Hamsters

Safety and Pharmacokinetics of Single Intravenous Dose of MGAWN1, a Novel Monoclonal Antibody to West Nile Virus

Vorinostat Renders the Replication-Competent Latent Reservoir of Human Immunodeficiency Virus (HIV) Vulnerable to Clearance by CD8 T Cells

Margetuximab plus pembrolizumab in patients with previously treated, HER2-positive gastro-oesophageal adenocarcinoma (CP-MGAH22–05): a single-arm, phase 1b–2 trial

Efficacy of Margetuximab vs Trastuzumab in Patients With Pretreated ERBB2-Positive Advanced Breast Cancer: A Phase 3 Randomized Clinical Trial

Envelope-specific antibodies and antibody-derived molecules for treating and curing HIV infection

Correlation Between TIGIT Expression on CD8+ T Cells and Higher Cytotoxic Capacity

Anti-tumor activity and toxicokinetics analysis of MGAH22, an anti-HER2 monoclonal antibody with enhanced Fcγ receptor binding properties

SMAC Mimetic Plus Triple-Combination Bispecific HIVxCD3 Retargeting Molecules in SHIV.C.CH505-Infected, Antiretroviral Therapy-Suppressed Rhesus Macaques

Dual-Affinity Re-Targeting proteins direct T cell-mediated cytolysis of latently HIV-infected cells

Defining Limits of Treatment with Humanized Neutralizing Monoclonal Antibody for West Nile Virus Neurological Infection in a Hamster Model

Margetuximab in HER2-positive metastatic breast cancer

CD19xCD3 DART protein mediates human B-cell depletion in vivo in humanized BLT mice

Cationic Lipids Enhance Cytokine and Cell Influx Levels in the Lung Following Administration of Plasmid: Cationic Lipid Complexes

The antiprogestin-dependent GeneSwitch ® system for regulated gene therapy

West Nile virus-induced acute flaccid paralysis is prevented by monoclonal antibody treatment when administered after infection of spinal cord neurons

Antiprogestin-controllable transgene regulation in vivo

Ligand-Dependent Regulation of Vascular Endothelial Growth Factor and Erythropoietin Expression by a Plasmid-Based Autoinducible GeneSwitch System

Enhanced animal growth via ligand-regulated GHRH myogenic-injectable vectors

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