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The AFT024 stromal cell line supports long-term ex vivo maintenance of engrafting multipotent human hematopoietic progenitors

Leukemia, 2002-03, Vol.16 (3), p.352-361

2002

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Transduction of Pluripotent Human Hematopoietic Stem Cells Demonstrated by Clonal Analysis after Engraftment in Immune-Deficient Mice

Proceedings of the National Academy of Sciences - PNAS, 1996-03, Vol.93 (6), p.2414-2419

1996

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Analysis of Optimal Conditions for Retroviral-Mediated Transduction of Primitive Human Hematopoietic Cells

Blood, 1995-07, Vol.86 (1), p.101-110

1995

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CD34 : To select or not to select? That is the question

Leukemia, 2000-05, Vol.14 (5), p.773-776

2000

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Reduction in levels of the cyclin-dependent kinase inhibitor p27(kip-1) coupled with transforming growth factor beta neutralization induces cell-cycle entry and increases retroviral transduction of primitive human hematopoietic cells

Proceedings of the National Academy of Sciences - PNAS, 1998-10, Vol.95 (22), p.13006-13011

1998

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Sustained human hematopoiesis in immunodeficient mice by cotransplantation of marrow stroma expressing human interleukin-3 : analysis of gene transduction of long-lived progenitors

Blood, 1994-05, Vol.83 (10), p.3041-3051

1994

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The number and generative capacity of human B lymphocyte progenitors, measured in vitro and in vivo, is higher in umbilical cord blood than in adult or pediatric bone marrow

Bone marrow transplantation (Basingstoke), 1999-12, Vol.24 (11), p.1167-1176

1999

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FLT3 ligand preserves the ability of human CD34+ progenitors to sustain long-term hematopoiesis in immune-deficient mice after ex vivo retroviral-mediated transduction

Blood, 1997-01, Vol.89 (2), p.446-456

1997

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Engraftment and retroviral marking of CD34+ and CD34+CD38- human hematopoietic progenitors assessed in immune-deficient mice

Blood, 1998-02, Vol.91 (4), p.1243-1255

1998

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Molecular control of cell cycle progression in primary human hematopoietic stem cells : methods to increase levels of retroviral-mediated transduction

Leukemia, 1999-10, Vol.13 (10), p.1473-1480

1999

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IL-7 Enhances the Responsiveness of Human T Cells That Develop in the Bone Marrow of Athymic Mice

The Journal of immunology (1950), 2001-01, Vol.166 (1), p.170-181

2001

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Adhesion to Fibronectin Maintains Regenerative Capacity During Ex Vivo Culture and Transduction of Human Hematopoietic Stem and Progenitor Cells

Blood, 1998-12, Vol.92 (12), p.4612-4621

1998

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T lymphocytes with a normal ADA gene accumulate after transplantation of transduced autologous umbilical cord blood CD34 + cells in ADA-deficient SCID neonates

Nature medicine, 1998-07, Vol.4 (7), p.775-780

1998

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Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency

Nature medicine, 1995-10, Vol.1 (10), p.1017-1023

1995

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Retroviral vector-mediated gene transfer into primitive human hematopoietic progenitor cells: effects of mast cell growth factor (MGF) combined with other cytokines

Experimental hematology, 1992-10, Vol.20 (9), p.1065

1992

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Cbl functions downstream of Src kinases in Fc gamma RI signaling in primary human macrophages

Journal of leukocyte biology, 1999-04, Vol.65 (4), p.523-534

1999

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Comparison of the effects of growth factors on retroviral vector-mediated gene transfer and the proliferative status of human hematopoietic progenitor cells

Human gene therapy, 1990, Vol.1 (3), p.257-268

1990

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The presence of an autologous marrow stromal cell layer increases glucocerebrosidase gene transduction of long-term culture initiating cells (LTCICs) from the bone marrow of a patient with Gaucher disease

Gene therapy, 1995-10, Vol.2 (8), p.512

1995

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Retroviral-mediated transfer of the human glucocerebrosidase gene into cultured gaucher bone marrow

The Journal of clinical investigation, 1992-08, Vol.90 (2), p.342-348

1992

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Clonal diversity of primitive human hematopoietic progenitors following retroviral marking and long-term engraftment in immune-deficient mice

Experimental hematology, 1997-12, Vol.25 (13), p.1357

1997

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Mesenchymal stromal cell variables influencing clinical potency: the impact of viability, fitness, route of administration and host predisposition

Cytotherapy (Oxford, England), 2021-05, Vol.23 (5), p.368-372

2021

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Cell-based therapies for coronavirus disease 2019: proper clinical investigations are essential

Cytotherapy (Oxford, England), 2020-11, Vol.22 (11), p.602-605

2020

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Immunodeficient mice as models of human hematopoietic stem cell engraftment

Current Opinion in Immunology, 1999-10, Vol.11 (5), p.532-537

1999

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Expression of Human Glucocerebrosidase in Murine Long-Term Bone Marrow Cultures After Retroviral Vector-Mediated Transfer

Blood, 1990-02, Vol.75 (3), p.787-797

1990

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Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells

Blood, 2006-03, Vol.107 (5), p.2162-2169

2006

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The AFT024 stromal cell line supports long-term ex vivo maintenance of engrafting multipotent human hematopoietic progenitors

Transduction of Pluripotent Human Hematopoietic Stem Cells Demonstrated by Clonal Analysis after Engraftment in Immune-Deficient Mice

Analysis of Optimal Conditions for Retroviral-Mediated Transduction of Primitive Human Hematopoietic Cells

CD34 : To select or not to select? That is the question

Reduction in levels of the cyclin-dependent kinase inhibitor p27(kip-1) coupled with transforming growth factor beta neutralization induces cell-cycle entry and increases retroviral transduction of primitive human hematopoietic cells

Sustained human hematopoiesis in immunodeficient mice by cotransplantation of marrow stroma expressing human interleukin-3 : analysis of gene transduction of long-lived progenitors

The number and generative capacity of human B lymphocyte progenitors, measured in vitro and in vivo, is higher in umbilical cord blood than in adult or pediatric bone marrow

FLT3 ligand preserves the ability of human CD34+ progenitors to sustain long-term hematopoiesis in immune-deficient mice after ex vivo retroviral-mediated transduction

Engraftment and retroviral marking of CD34+ and CD34+CD38- human hematopoietic progenitors assessed in immune-deficient mice

Molecular control of cell cycle progression in primary human hematopoietic stem cells : methods to increase levels of retroviral-mediated transduction

IL-7 Enhances the Responsiveness of Human T Cells That Develop in the Bone Marrow of Athymic Mice

Adhesion to Fibronectin Maintains Regenerative Capacity During Ex Vivo Culture and Transduction of Human Hematopoietic Stem and Progenitor Cells

T lymphocytes with a normal ADA gene accumulate after transplantation of transduced autologous umbilical cord blood CD34 + cells in ADA-deficient SCID neonates

Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency

Retroviral vector-mediated gene transfer into primitive human hematopoietic progenitor cells: effects of mast cell growth factor (MGF) combined with other cytokines

Cbl functions downstream of Src kinases in Fc gamma RI signaling in primary human macrophages

Comparison of the effects of growth factors on retroviral vector-mediated gene transfer and the proliferative status of human hematopoietic progenitor cells

The presence of an autologous marrow stromal cell layer increases glucocerebrosidase gene transduction of long-term culture initiating cells (LTCICs) from the bone marrow of a patient with Gaucher disease

Retroviral-mediated transfer of the human glucocerebrosidase gene into cultured gaucher bone marrow

Clonal diversity of primitive human hematopoietic progenitors following retroviral marking and long-term engraftment in immune-deficient mice

Mesenchymal stromal cell variables influencing clinical potency: the impact of viability, fitness, route of administration and host predisposition

Cell-based therapies for coronavirus disease 2019: proper clinical investigations are essential

Immunodeficient mice as models of human hematopoietic stem cell engraftment

Expression of Human Glucocerebrosidase in Murine Long-Term Bone Marrow Cultures After Retroviral Vector-Mediated Transfer

Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells

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