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Nasal delivery of an IgM offers broad protection from SARS-CoV-2 variants

Nature (London), 2021-07, Vol.595 (7869), p.718-723

2021

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1078 Agonistic CD40 IgM antibodies enhance immune responses beyond that of IgGs

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1187-A1187

2023

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711 IGM-7354 is an anti-PD-L1 IgM antibody and IL-15 cytokine fusion that enhances NK and CD8+ T cell proliferation and tumor cytotoxicity plus potently reverses T cell exhaustion

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A740-A740

2021

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1362 Agonistic 4–1BB IgM antibodies enhance CD8+ T cell proliferation and proinflammatory cytokine secretion in vitro and in vivo

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1518-A1518

2023

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Lack of the Vitamin D Receptor is Associated with Reduced Epidermal Differentiation and Hair Follicle Growth

Journal of investigative dermatology, 2002-01, Vol.118 (1), p.11-16

2002

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569 Targeting IL-15 delivery to PD-L1 expressing tumors with an Anti-PD-L1-IL-15 cytokine fusion IgM to enhance T Cell and NK Cell Mediated tumor cytotoxicity

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A342-A343

2020

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Stimulation of PPARα Promotes Epidermal Keratinocyte Differentiation In Vivo

Journal of investigative dermatology, 2000-09, Vol.115 (3), p.353-360

2000

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Role of protein kinase C α in calcium induced keratinocyte differentiation: Defective regulation in squamous cell carcinoma

Journal of cellular physiology, 2003-05, Vol.195 (2), p.249-259

2003

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Oxysterols Induce Differentiation in Human Keratinocytes and Increase Ap-1-Dependent Involucrin Transcription

Journal of investigative dermatology, 2000-03, Vol.114 (3), p.545-553

2000

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Farnesol Stimulates Differentiation in Epidermal Keratinocytes via PPARα

The Journal of biological chemistry, 2000-04, Vol.275 (15), p.11484-11491

2000

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Cholesterol sulfate stimulates involucrin transcription in keratinocytes by increasing Fra-1, Fra-2, and Jun D

Journal of lipid research, 2001-03, Vol.42 (3), p.390-398

2001

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Igm-2644, a Novel CD38xCD3 Bispecific IgM T Cell Engager Demonstrates Potent Efficacy on Myeloma Cells with an Improved Preclinical Safety Profile

Blood, 2022-11, Vol.140 (Supplement 1), p.6010-6011

2022

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Requirement of an AP-1 Site in the Calcium Response Region of the Involucrin Promoter

The Journal of biological chemistry, 2000-08, Vol.275 (31), p.24080-24088

2000

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Abstract 1702: Multimeric anti-DR5 IgM antibody displays potent cytotoxicity in vitro and promotes tumor regression in vivo

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.1702-1702

2017

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Abstract 5664: A bispecific IgM antibody format for enhanced T cell dependent killing with minimal cytokine release

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.5664-5664

2020

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Lymphoma cell-killing activity and cytokine release by CD20-directed bispecific IgM antibody-based T-cell engager (IGM-2323)

Journal of clinical oncology, 2020-05, Vol.38 (15_suppl), p.e15007-e15007

2020

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High Avidity IgM-Based CD20xCD3 Bispecific Antibody (IGM-2323) for Enhanced T-Cell Dependent Killing with Minimal Cytokine Release

Blood, 2019-11, Vol.134 (Supplement_1), p.1574-1574

2019

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Abstract 4179: High valency of IGM-2323, a CD20xCD3 IgM bispecific T cell engager, displaces rituximab binding and induces potent B lymphoma cell killing

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.4179-4179

2022

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Abstract 3438: Enhanced NK and CD8+ T cell proliferation, tumor cytotoxicity and reversal of T cell exhaustion with IGM-7354, an anti-PD-L1 IgM antibody and IL-15 cytokine fusion

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.3438-3438

2022

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Abstract 5660: IGM-7354, an immunocytokine with IL-15 fused to an anti-PD-L1 IgM, induces NK and CD8+ T cell mediated cytotoxicity of PD-L1-positive tumor cells

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.5660-5660

2023

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Abstract 2959: Novel CD38xCD3 bispecific IgM T cell engager, IGM-2644, potently kills multiple myeloma cells though complement and T cell dependent mechanisms

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.2959-2959

2023

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The Vitamin D Response Element of the Involucrin Gene Mediates its Regulation by 1,25-Dihydroxyvitamin D3

Journal of investigative dermatology, 2002-11, Vol.119 (5), p.1109-1113

2002

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Neural regulation of the formation of skeletal muscle phosphorylase kinase holoenzyme in adult and developing rat muscle

Biochemical journal, 1997-08, Vol.325 ( Pt 3) (3), p.793-800

1997

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Identification of cell surface and secreted proteins essential for tumor cell survival using a genetic suppressor element screen

Oncogene, 2004-10, Vol.23 (49), p.8158-8170

2004

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Squamous cell carcinomas fail to respond to the prodifferentiating actions of 1,25(OH)2D: why?

Recent results in cancer research, 2003, Vol.164, p.111

2003

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Nasal delivery of an IgM offers broad protection from SARS-CoV-2 variants

1078 Agonistic CD40 IgM antibodies enhance immune responses beyond that of IgGs

711 IGM-7354 is an anti-PD-L1 IgM antibody and IL-15 cytokine fusion that enhances NK and CD8+ T cell proliferation and tumor cytotoxicity plus potently reverses T cell exhaustion

1362 Agonistic 4–1BB IgM antibodies enhance CD8+ T cell proliferation and proinflammatory cytokine secretion in vitro and in vivo

Lack of the Vitamin D Receptor is Associated with Reduced Epidermal Differentiation and Hair Follicle Growth

569 Targeting IL-15 delivery to PD-L1 expressing tumors with an Anti-PD-L1-IL-15 cytokine fusion IgM to enhance T Cell and NK Cell Mediated tumor cytotoxicity

Stimulation of PPARα Promotes Epidermal Keratinocyte Differentiation In Vivo

Role of protein kinase C α in calcium induced keratinocyte differentiation: Defective regulation in squamous cell carcinoma

Oxysterols Induce Differentiation in Human Keratinocytes and Increase Ap-1-Dependent Involucrin Transcription

Farnesol Stimulates Differentiation in Epidermal Keratinocytes via PPARα

Cholesterol sulfate stimulates involucrin transcription in keratinocytes by increasing Fra-1, Fra-2, and Jun D

Igm-2644, a Novel CD38xCD3 Bispecific IgM T Cell Engager Demonstrates Potent Efficacy on Myeloma Cells with an Improved Preclinical Safety Profile

Requirement of an AP-1 Site in the Calcium Response Region of the Involucrin Promoter

Abstract 1702: Multimeric anti-DR5 IgM antibody displays potent cytotoxicity in vitro and promotes tumor regression in vivo

Abstract 5664: A bispecific IgM antibody format for enhanced T cell dependent killing with minimal cytokine release

Lymphoma cell-killing activity and cytokine release by CD20-directed bispecific IgM antibody-based T-cell engager (IGM-2323)

High Avidity IgM-Based CD20xCD3 Bispecific Antibody (IGM-2323) for Enhanced T-Cell Dependent Killing with Minimal Cytokine Release

Abstract 4179: High valency of IGM-2323, a CD20xCD3 IgM bispecific T cell engager, displaces rituximab binding and induces potent B lymphoma cell killing

Abstract 3438: Enhanced NK and CD8+ T cell proliferation, tumor cytotoxicity and reversal of T cell exhaustion with IGM-7354, an anti-PD-L1 IgM antibody and IL-15 cytokine fusion

Abstract 5660: IGM-7354, an immunocytokine with IL-15 fused to an anti-PD-L1 IgM, induces NK and CD8+ T cell mediated cytotoxicity of PD-L1-positive tumor cells

Abstract 2959: Novel CD38xCD3 bispecific IgM T cell engager, IGM-2644, potently kills multiple myeloma cells though complement and T cell dependent mechanisms

The Vitamin D Response Element of the Involucrin Gene Mediates its Regulation by 1,25-Dihydroxyvitamin D3

Neural regulation of the formation of skeletal muscle phosphorylase kinase holoenzyme in adult and developing rat muscle

Identification of cell surface and secreted proteins essential for tumor cell survival using a genetic suppressor element screen

Squamous cell carcinomas fail to respond to the prodifferentiating actions of 1,25(OH)2D: why?

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