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ABCG2 Polymorphism Markedly Affects the Pharmacokinetics of Atorvastatin and Rosuvastatin

Clinical pharmacology and therapeutics, 2009-08, Vol.86 (2), p.197-203

2009

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Carboxylesterase 1 c.428G>A single nucleotide variation increases the antiplatelet effects of clopidogrel by reducing its hydrolysis in humans

Clinical pharmacology and therapeutics, 2015-06, Vol.97 (6), p.650-658

2015

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Glucuronidation Converts Clopidogrel to a Strong Time-Dependent Inhibitor of CYP2C8: A Phase II Metabolite as a Perpetrator of Drug-Drug Interactions

Clinical pharmacology and therapeutics, 2014-10, Vol.96 (4), p.498-507

2014

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Carboxylesterase 1 Polymorphism Impairs Oseltamivir Bioactivation in Humans

Clinical pharmacology and therapeutics, 2012-07, Vol.92 (1), p.68-71

2012

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Grapefruit Juice Inhibits the Metabolic Activation of Clopidogrel

Clinical pharmacology and therapeutics, 2014-03, Vol.95 (3), p.307-313

2014

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Different Effects of SLCO1B1 Polymorphism on the Pharmacokinetics of Atorvastatin and Rosuvastatin

Clinical pharmacology and therapeutics, 2007-12, Vol.82 (6), p.726-733

2007

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Grapefruit Juice Greatly Reduces the Plasma Concentrations of the OATP2B1 and CYP3A4 Substrate Aliskiren

Clinical pharmacology and therapeutics, 2010-09, Vol.88 (3), p.339-342

2010

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Effect of intravenous lipid emulsion on bupivacaine plasma concentration in humans

Anaesthesia, 2012-06, Vol.67 (6), p.600-605

2012

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The Effect of Gemfibrozil on Repaglinide Pharmacokinetics Persists for at Least 12 h After the Dose: Evidence for Mechanism‐based Inhibition of CYP2C8 In Vivo

Clinical pharmacology and therapeutics, 2008-09, Vol.84 (3), p.403-411

2008

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Potent mechanism‐based inhibition of CYP3A4 by imatinib explains its liability to interact with CYP3A4 substrates

British journal of pharmacology, 2012-04, Vol.165 (8), p.2787-2798

2012

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Plasma Concentrations of Oral Oxycodone Are Greatly Increased in the Elderly

Clinical pharmacology and therapeutics, 2008-10, Vol.84 (4), p.462-467

2008

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Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics and pharmacodynamics of repaglinide: potentially hazardous interaction between gemfibrozil and repaglinide

Diabetologia, 2003-03, Vol.46 (3), p.347-351

2003

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Mechanism-Based Inactivation of CYP2C8 by Gemfibrozil Occurs Rapidly in Humans

Clinical pharmacology and therapeutics, 2011-04, Vol.89 (4), p.579-586

2011

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UDP‐Glucuronosyltransferase (UGT) Polymorphisms Affect Atorvastatin Lactonization In Vitro and In Vivo

Clinical pharmacology and therapeutics, 2010-01, Vol.87 (1), p.65-73

2010

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Gemfibrozil Is a Strong Inactivator of CYP2C8 in Very Small Multiple Doses

Clinical pharmacology and therapeutics, 2012-05, Vol.91 (5), p.846-855

2012

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Effects of Gemfibrozil and Atorvastatin on the Pharmacokinetics of Repaglinide in Relation to SLCO1B1 Polymorphism

Clinical pharmacology and therapeutics, 2008-10, Vol.84 (4), p.488-496

2008

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Gemfibrozil Impairs Imatinib Absorption and Inhibits the CYP2C8-Mediated Formation of Its Main Metabolite

Clinical pharmacology and therapeutics, 2013-09, Vol.94 (3), p.383-393

2013

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Gemfibrozil Markedly Increases the Plasma Concentrations of Montelukast: A Previously Unrecognized Role for CYP2C8 in the Metabolism of Montelukast

Clinical pharmacology and therapeutics, 2010-08, Vol.88 (2), p.223-230

2010

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Oxycodone clearance is markedly reduced with advancing age: a population pharmacokinetic study

British journal of anaesthesia : BJA, 2012-03, Vol.108 (3), p.491-498

2012

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Effects of Daily Ingestion of Cranberry Juice on the Pharmacokinetics of Warfarin, Tizanidine, and Midazolam-Probes of CYP2C9, CYP1A2, and CYP3A4

Clinical pharmacology and therapeutics, 2007-06, Vol.81 (6), p.833-839

2007

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Gemfibrozil considerably increases the plasma concentrations of rosiglitazone

Diabetologia, 2003-10, Vol.46 (10), p.1319-1323

2003

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ABCB1 Haplotypes Differentially Affect the Pharmacokinetics of the Acid and Lactone Forms of Simvastatin and Atorvastatin

Clinical pharmacology and therapeutics, 2008-10, Vol.84 (4), p.457-461

2008

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Dexmedetomidine inhibits gastric emptying and oro-caecal transit in healthy volunteers

British journal of anaesthesia : BJA, 2011-04, Vol.106 (4), p.522-527

2011

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Effects of orange juice on the pharmacokinetics of atenolol

European journal of clinical pharmacology, 2005-07, Vol.61 (5-6), p.337-340

2005

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Amiodarone Interacts with Simvastatin but not with Pravastatin Disposition Kinetics

Clinical pharmacology and therapeutics, 2007-05, Vol.81 (5), p.679-684

2007

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ABCG2 Polymorphism Markedly Affects the Pharmacokinetics of Atorvastatin and Rosuvastatin

Carboxylesterase 1 c.428G>A single nucleotide variation increases the antiplatelet effects of clopidogrel by reducing its hydrolysis in humans

Glucuronidation Converts Clopidogrel to a Strong Time-Dependent Inhibitor of CYP2C8: A Phase II Metabolite as a Perpetrator of Drug-Drug Interactions

Carboxylesterase 1 Polymorphism Impairs Oseltamivir Bioactivation in Humans

Grapefruit Juice Inhibits the Metabolic Activation of Clopidogrel

Different Effects of SLCO1B1 Polymorphism on the Pharmacokinetics of Atorvastatin and Rosuvastatin

Grapefruit Juice Greatly Reduces the Plasma Concentrations of the OATP2B1 and CYP3A4 Substrate Aliskiren

Effect of intravenous lipid emulsion on bupivacaine plasma concentration in humans

The Effect of Gemfibrozil on Repaglinide Pharmacokinetics Persists for at Least 12 h After the Dose: Evidence for Mechanism‐based Inhibition of CYP2C8 In Vivo

Potent mechanism‐based inhibition of CYP3A4 by imatinib explains its liability to interact with CYP3A4 substrates

Plasma Concentrations of Oral Oxycodone Are Greatly Increased in the Elderly

Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics and pharmacodynamics of repaglinide: potentially hazardous interaction between gemfibrozil and repaglinide

Mechanism-Based Inactivation of CYP2C8 by Gemfibrozil Occurs Rapidly in Humans

UDP‐Glucuronosyltransferase (UGT) Polymorphisms Affect Atorvastatin Lactonization In Vitro and In Vivo

Gemfibrozil Is a Strong Inactivator of CYP2C8 in Very Small Multiple Doses

Effects of Gemfibrozil and Atorvastatin on the Pharmacokinetics of Repaglinide in Relation to SLCO1B1 Polymorphism

Gemfibrozil Impairs Imatinib Absorption and Inhibits the CYP2C8-Mediated Formation of Its Main Metabolite

Gemfibrozil Markedly Increases the Plasma Concentrations of Montelukast: A Previously Unrecognized Role for CYP2C8 in the Metabolism of Montelukast

Oxycodone clearance is markedly reduced with advancing age: a population pharmacokinetic study

Effects of Daily Ingestion of Cranberry Juice on the Pharmacokinetics of Warfarin, Tizanidine, and Midazolam-Probes of CYP2C9, CYP1A2, and CYP3A4

Gemfibrozil considerably increases the plasma concentrations of rosiglitazone

ABCB1 Haplotypes Differentially Affect the Pharmacokinetics of the Acid and Lactone Forms of Simvastatin and Atorvastatin

Dexmedetomidine inhibits gastric emptying and oro-caecal transit in healthy volunteers

Effects of orange juice on the pharmacokinetics of atenolol

Amiodarone Interacts with Simvastatin but not with Pravastatin Disposition Kinetics

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