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Overall survival analysis of EXAM, a phase III trial of cabozantinib in patients with radiographically progressive medullary thyroid carcinoma

Annals of oncology, 2017-11, Vol.28 (11), p.2813-2819

2017

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Methylation-Specific PCR: A Novel PCR Assay for Methylation Status of CpG Islands

Proceedings of the National Academy of Sciences - PNAS, 1996-09, Vol.93 (18), p.9821-9826

1996

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A phase I trial of vertical inhibition of IGF signalling using cixutumumab, an anti-IGF-1R antibody, and selumetinib, an MEK 1/2 inhibitor, in advanced solid tumours

British journal of cancer, 2015-01, Vol.112 (1), p.24-31

2015

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STAT3 attenuates EGFR-mediated ERK activation and cell survival during oxidant stress in mouse proximal tubular cells

Kidney international, 2006-08, Vol.70 (4), p.669-674

2006

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Epidermal growth factor receptor-independent constitutive activation of STAT3 in head and neck squamous cell carcinoma is mediated by the autocrine/paracrine stimulation of the interleukin 6/gp130 cytokine system

Cancer research (Chicago, Ill.), 2003-06, Vol.63 (11), p.2948-2956

2003

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Notch signaling induces cell cycle arrest in small cell lung cancer cells

Cancer research (Chicago, Ill.), 2001-04, Vol.61 (7), p.3200-3205

2001

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Constitutive achaete-scute homologue-1 promotes airway dysplasia and lung neuroendocrine tumors in transgenic mice

Cancer research (Chicago, Ill.), 2000-08, Vol.60 (15), p.4005-4009

2000

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p53 activates expression of HIC-1 , a new candidate tumour suppressor gene on 17p13.3

Nature medicine, 1995-06, Vol.1 (6), p.570-577

1995

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The Ras/Raf/MEK/Extracellular Signal-Regulated Kinase Pathway Induces Autocrine-Paracrine Growth Inhibition via the Leukemia Inhibitory Factor/JAK/STAT Pathway

Molecular and Cellular Biology, 2003-01, Vol.23 (2), p.543-554

2003

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Notch Signaling Induces Rapid Degradation of Achaete-Scute Homolog 1

Molecular and Cellular Biology, 2002-05, Vol.22 (9), p.3129-3139

2002

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Increased Cytosine DNA-Methyltransferase Activity During Colon Cancer Progression

JNCI : Journal of the National Cancer Institute, 1993-08, Vol.85 (15), p.1235-1240

1993

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Expression of an Exogenous Eukaryotic DNA Methyltransferase Gene Induces Transformation of NIH 3T3 Cells

Proceedings of the National Academy of Sciences - PNAS, 1993-10, Vol.90 (19), p.8891-8895

1993

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High Expression of the DNA Methyltransferase Gene Characterizes Human Neoplastic Cells and Progression Stages of Colon Cancer

Proceedings of the National Academy of Sciences - PNAS, 1991-04, Vol.88 (8), p.3470-3474

1991

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An achaete-scute homologue essential for neuroendocrine differentiation in the lung

Nature (London), 1997-04, Vol.386 (6627), p.852-855

1997

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Distinct Hypermethylation Patterns Occur at Altered Chromosome Loci in Human Lung and Colon Cancer

Proceedings of the National Academy of Sciences - PNAS, 1992-03, Vol.89 (5), p.1929-1933

1992

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Conservation of the Drosophila Lateral Inhibition Pathway in Human Lung Cancer: A Hairy-Related Protein (HES-1) Directly Represses Achaete-Scute Homolog-1 Expression

Proceedings of the National Academy of Sciences - PNAS, 1997-05, Vol.94 (10), p.5355-5360

1997

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Identification of a Human Achaete-Scute Homolog Highly Expressed in Neuroendocrine Tumors

Proceedings of the National Academy of Sciences - PNAS, 1993-06, Vol.90 (12), p.5648-5652

1993

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RREB-1, a novel zinc finger protein, is involved in the differentiation response to Ras in human medullary thyroid carcinomas

Molecular and Cellular Biology, 1996-10, Vol.16 (10), p.5335-5345

1996

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Reactive Oxygen Species Are Critical for the Growth and Differentiation of Medullary Thyroid Carcinoma Cells

Clinical cancer research, 2000-09, Vol.6 (9), p.3783-3787

2000

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The Short Arm of Chromosome 11 is a ``Hot Spot'' for Hypermethylation in Human Neoplasia

Proceedings of the National Academy of Sciences - PNAS, 1988-08, Vol.85 (15), p.5693-5697

1988

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Isolation and characterization of the cDNA encoding human DNA methyltransferase

Nucleic acids research, 1992-05, Vol.20 (9), p.2287-2291

1992

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Roles of trk Family Neurotrophin Receptors in Medullary Thyroid Carcinoma Development and Progression

Proceedings of the National Academy of Sciences - PNAS, 1999-04, Vol.96 (8), p.4540-4545

1999

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Combretastatin A-4 and doxorubicin combination treatment is effective in a preclinical model of human medullary thyroid carcinoma

Oncology reports, 2001-01, Vol.8 (1), p.157

2001

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Regional DNA hypermethylation at D17S5 precedes 17p structural changes in the progression of renal tumors

Cancer research (Chicago, Ill.), 1993-06, Vol.53 (12), p.2719-2722

1993

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BARX2 induces cadherin 6 expression and is a functional suppressor of ovarian cancer progression

Cancer research (Chicago, Ill.), 2001-10, Vol.61 (19), p.6977-6981

2001

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Overall survival analysis of EXAM, a phase III trial of cabozantinib in patients with radiographically progressive medullary thyroid carcinoma

Methylation-Specific PCR: A Novel PCR Assay for Methylation Status of CpG Islands

A phase I trial of vertical inhibition of IGF signalling using cixutumumab, an anti-IGF-1R antibody, and selumetinib, an MEK 1/2 inhibitor, in advanced solid tumours

STAT3 attenuates EGFR-mediated ERK activation and cell survival during oxidant stress in mouse proximal tubular cells

Epidermal growth factor receptor-independent constitutive activation of STAT3 in head and neck squamous cell carcinoma is mediated by the autocrine/paracrine stimulation of the interleukin 6/gp130 cytokine system

Notch signaling induces cell cycle arrest in small cell lung cancer cells

Constitutive achaete-scute homologue-1 promotes airway dysplasia and lung neuroendocrine tumors in transgenic mice

p53 activates expression of HIC-1 , a new candidate tumour suppressor gene on 17p13.3

The Ras/Raf/MEK/Extracellular Signal-Regulated Kinase Pathway Induces Autocrine-Paracrine Growth Inhibition via the Leukemia Inhibitory Factor/JAK/STAT Pathway

Notch Signaling Induces Rapid Degradation of Achaete-Scute Homolog 1

Increased Cytosine DNA-Methyltransferase Activity During Colon Cancer Progression

Expression of an Exogenous Eukaryotic DNA Methyltransferase Gene Induces Transformation of NIH 3T3 Cells

High Expression of the DNA Methyltransferase Gene Characterizes Human Neoplastic Cells and Progression Stages of Colon Cancer

An achaete-scute homologue essential for neuroendocrine differentiation in the lung

Distinct Hypermethylation Patterns Occur at Altered Chromosome Loci in Human Lung and Colon Cancer

Conservation of the Drosophila Lateral Inhibition Pathway in Human Lung Cancer: A Hairy-Related Protein (HES-1) Directly Represses Achaete-Scute Homolog-1 Expression

Identification of a Human Achaete-Scute Homolog Highly Expressed in Neuroendocrine Tumors

RREB-1, a novel zinc finger protein, is involved in the differentiation response to Ras in human medullary thyroid carcinomas

Reactive Oxygen Species Are Critical for the Growth and Differentiation of Medullary Thyroid Carcinoma Cells

The Short Arm of Chromosome 11 is a ``Hot Spot'' for Hypermethylation in Human Neoplasia

Isolation and characterization of the cDNA encoding human DNA methyltransferase

Roles of trk Family Neurotrophin Receptors in Medullary Thyroid Carcinoma Development and Progression

Combretastatin A-4 and doxorubicin combination treatment is effective in a preclinical model of human medullary thyroid carcinoma

Regional DNA hypermethylation at D17S5 precedes 17p structural changes in the progression of renal tumors

BARX2 induces cadherin 6 expression and is a functional suppressor of ovarian cancer progression

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