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The Prokineticins: Neuromodulators and Mediators of Inflammation and Myeloid Cell-Dependent Angiogenesis

Physiological reviews, 2018-04, Vol.98 (2), p.1055-1082

2018

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Targeting the Prokineticin System to Control Chronic Pain and Inflammation

Current medicinal chemistry, 2018-01, Vol.25 (32), p.3883-3894

2018

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The Involvement of Post-Translational Modifications in Alzheimer's Disease

Current Alzheimer research, 2018-02, Vol.15 (4), p.313-335

2018

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In vitro and in vivo Pharmacological Activities of 14- O -Phenylpropyloxymorphone, a Potent Mixed Mu/Delta/Kappa-Opioid Receptor Agonist With Reduced Constipation in Mice

Frontiers in pharmacology, 2018-08, Vol.9, p.1002-1002

2018

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Antagonism of the Prokineticin System Prevents and Reverses Allodynia and Inflammation in a Mouse Model of Diabetes

PloS one, 2016-01, Vol.11 (1), p.e0146259-e0146259

2016

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Bv8-prokineticins and their receptors: modulators of pain

Current pharmaceutical biotechnology, 2011-10, Vol.12 (10), p.1720-1727

2011

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A new convenient synthetic method and preliminary pharmacological characterization of triazinediones as prokineticin receptor antagonists

European journal of medicinal chemistry, 2014-06, Vol.81, p.334-340

2014

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chemokine Bv8/prokineticin 2 is up-regulated in inflammatory granulocytes and modulates inflammatory pain

Proceedings of the National Academy of Sciences - PNAS, 2009-08, Vol.106 (34), p.14646-14651

2009

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Sensitization of Transient Receptor Potential Vanilloid 1 by the Prokineticin Receptor Agonist Bv8

The Journal of neuroscience, 2006-05, Vol.26 (19), p.5109-5116

2006

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Bv8, the amphibian homologue of the mammalian prokineticins, induces a proinflammatory phenotype of mouse macrophages

British journal of pharmacology, 2006-01, Vol.147 (2), p.225-234

2006

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Bv8/PK2 and prokineticin receptors: a druggable pronociceptive system

Current opinion in pharmacology, 2012-02, Vol.12 (1), p.62-66

2012

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The prokineticin receptor agonist Bv8 decreases IL-10 and IL-4 production in mice splenocytes by activating prokineticin receptor-1

BMC immunology, 2008-10, Vol.9 (1), p.60-60, Article 60

2008

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Critical role for prokineticin 2 in CNS autoimmunity

Neurology : neuroimmunology & neuroinflammation, 2015-06, Vol.2 (3)

2015

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Nociceptive sensitization by the secretory protein Bv8

British journal of pharmacology, 2002-12, Vol.137 (8), p.1147-1154

2002

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Bv8, a small protein from frog skin and its homologue from snake venom induce hyperalgesia in rats

European journal of pharmacology, 1999-06, Vol.374 (2), p.189-196

1999

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Modulators of Pain: Bv8 and Prokineticins

Current neuropharmacology, 2006-07, Vol.4 (3), p.207-215

2006

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PK2β ligand, a splice variant of prokineticin 2, is able to modulate and drive signaling through PKR1 receptor

Neuropeptides (Edinburgh), 2018-10, Vol.71, p.32-42

2018

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The prokineticin receptor antagonist PC1 rescues memory impairment induced by β amyloid administration through the modulation of prokineticin system

Neuropharmacology, 2019-11, Vol.158, p.107739, Article 107739

2019

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Bv8/Prokineticin proteins and their receptors

Life sciences (1973), 2007-09, Vol.81 (14), p.1103-1116

2007

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Prokineticins are neuroprotective in models of cerebral ischemia and ischemic tolerance in vitro

Neuropharmacology, 2016-09, Vol.108, p.39-48

2016

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Abstract 1437: Relationship of G-CSF related bone pain (BP) with Bv8PK2 expression in breast cancer (BC) patients (pts) treated with FEC100 adjuvant chemotherapy (CT)

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.1437-1437

2016

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Abstract 1437: Relationship of G-CSF related bone pain (BP) with Bv8/PK2 expression in breast cancer (BC) patients (pts) treated with FEC100 adjuvant chemotherapy (CT)

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.1437-1437

2016

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Bv8/prokineticin 2 is involved in Aβ-induced neurotoxicity

Scientific reports, 2015-10, Vol.5 (1), p.15301, Article 15301

2015

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Prokineticin system modulation as a new target to counteract the amyloid beta toxicity induced by glutamatergic alterations in an in vitro model of Alzheimer's disease

Neuropharmacology, 2017-04, Vol.116, p.82-97

2017

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Prokineticin 2 Upregulation in the Peripheral Nervous System Has a Major Role in Triggering and Maintaining Neuropathic Pain in the Chronic Constriction Injury Model

BioMed research international, 2015-01, Vol.2015 (2015), p.1-15

2015

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The Prokineticins: Neuromodulators and Mediators of Inflammation and Myeloid Cell-Dependent Angiogenesis

Targeting the Prokineticin System to Control Chronic Pain and Inflammation

The Involvement of Post-Translational Modifications in Alzheimer's Disease

In vitro and in vivo Pharmacological Activities of 14- O -Phenylpropyloxymorphone, a Potent Mixed Mu/Delta/Kappa-Opioid Receptor Agonist With Reduced Constipation in Mice

Antagonism of the Prokineticin System Prevents and Reverses Allodynia and Inflammation in a Mouse Model of Diabetes

Bv8-prokineticins and their receptors: modulators of pain

A new convenient synthetic method and preliminary pharmacological characterization of triazinediones as prokineticin receptor antagonists

chemokine Bv8/prokineticin 2 is up-regulated in inflammatory granulocytes and modulates inflammatory pain

Sensitization of Transient Receptor Potential Vanilloid 1 by the Prokineticin Receptor Agonist Bv8

Bv8, the amphibian homologue of the mammalian prokineticins, induces a proinflammatory phenotype of mouse macrophages

Bv8/PK2 and prokineticin receptors: a druggable pronociceptive system

The prokineticin receptor agonist Bv8 decreases IL-10 and IL-4 production in mice splenocytes by activating prokineticin receptor-1

Critical role for prokineticin 2 in CNS autoimmunity

Nociceptive sensitization by the secretory protein Bv8

Bv8, a small protein from frog skin and its homologue from snake venom induce hyperalgesia in rats

Modulators of Pain: Bv8 and Prokineticins

PK2β ligand, a splice variant of prokineticin 2, is able to modulate and drive signaling through PKR1 receptor

The prokineticin receptor antagonist PC1 rescues memory impairment induced by β amyloid administration through the modulation of prokineticin system

Bv8/Prokineticin proteins and their receptors

Prokineticins are neuroprotective in models of cerebral ischemia and ischemic tolerance in vitro

Abstract 1437: Relationship of G-CSF related bone pain (BP) with Bv8PK2 expression in breast cancer (BC) patients (pts) treated with FEC100 adjuvant chemotherapy (CT)

Abstract 1437: Relationship of G-CSF related bone pain (BP) with Bv8/PK2 expression in breast cancer (BC) patients (pts) treated with FEC100 adjuvant chemotherapy (CT)

Bv8/prokineticin 2 is involved in Aβ-induced neurotoxicity

Prokineticin system modulation as a new target to counteract the amyloid beta toxicity induced by glutamatergic alterations in an in vitro model of Alzheimer's disease

Prokineticin 2 Upregulation in the Peripheral Nervous System Has a Major Role in Triggering and Maintaining Neuropathic Pain in the Chronic Constriction Injury Model

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