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Roles of Microglia in Neurodegenerative Diseases

YONAGO ACTA MEDICA, 2024, Vol.67 (1), p.1-8, Article 2024.02.001

Nakaso, Kazuhiro

2024

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Parkin controls dopamine utilization in human midbrain dopaminergic neurons derived from induced pluripotent stem cells

Nature communications, 2012-02, Vol.3 (1), p.668-668, Article 668

2012

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Caffeine activates the PI3K/Akt pathway and prevents apoptotic cell death in a Parkinson's disease model of SH-SY5Y cells

Neuroscience letters, 2008-02, Vol.432 (2), p.146-150

2008

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Molecular mechanisms underlying the promotion of wound repair by coenzyme Q10: PI3K/Akt signal activation via alterations to cell membrane domains

Journal of Clinical Biochemistry and Nutrition, 2022, Vol.70(3), pp.222-230

2022

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Parkin Protects Dopaminergic Neurons against Microtubule-depolymerizing Toxins by Attenuating Microtubule-associated Protein Kinase Activation

The Journal of biological chemistry, 2009-02, Vol.284 (6), p.4009-4017

2009

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System xc− in microglia is a novel therapeutic target for post-septic neurological and psychiatric illness

Scientific reports, 2019-05, Vol.9 (1), p.1-13, Article 7562

2019

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Increased plasma substance P and CGRP levels, and high ACE activity in migraineurs during headache-free periods

Pain (Amsterdam), 2007-04, Vol.128 (3), p.209-214

2007

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Oncogenic role of TYRO3 receptor tyrosine kinase in the progression of pancreatic cancer

Cancer letters, 2020-02, Vol.470, p.149-160

2020

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Depletion of p62 reduces nuclear inclusions and paradoxically ameliorates disease phenotypes in Huntington's model mice

Human molecular genetics, 2015-02, Vol.24 (4), p.1092-1105

2015

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PI3K is a key molecule in the Nrf2-mediated regulation of antioxidative proteins by hemin in human neuroblastoma cells

FEBS letters, 2003-07, Vol.546 (2), p.181-184

2003

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TYRO3 promotes chemoresistance via increased LC3 expression in pancreatic cancer

Translational oncology, 2023-02, Vol.28, p.101608-101608, Article 101608

2023

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Deficiency of p62/Sequestosome 1 causes hyperphagia due to leptin resistance in the brain

The Journal of neuroscience, 2013-09, Vol.33 (37), p.14767-14777

2013

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Nicotine enhances the malignant potential of human pancreatic cancer cells via activation of atypical protein kinase C

Biochimica et biophysica acta, 2016-11, Vol.1860 (11), p.2404-2415

2016

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Dopamine-mediated oxidation of methionine 127 in α-synuclein causes cytotoxicity and oligomerization of α-synuclein

PloS one, 2013-02, Vol.8 (2), p.e55068

2013

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Novel cytoprotective mechanism of anti-parkinsonian drug deprenyl: PI3K and Nrf2-derived induction of antioxidative proteins

Biochemical and biophysical research communications, 2006-01, Vol.339 (3), p.915-922

2006

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Preconditioning by Low Dose LPS Prevents Subsequent LPS-Induced Severe Liver Injury via Nrf2 Activation in Mice

YONAGO ACTA MEDICA, 2016-09, Vol.59 (3), p.223-231

2016

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Cytoprotective effect of chlorogenic acid against α-synuclein-related toxicity in catecholaminergic PC12 cells

Journal of Clinical Biochemistry and Nutrition, 2012, Vol.51(2), pp.122-127

2012

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Rice Bran Dietary Supplementation Improves Neurological Symptoms and Loss of Purkinje Cells in Vitamin E-Deficient Mice

YONAGO ACTA MEDICA, 2016-09, Vol.59 (3), p.188-195

2016

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Transcriptional activation of p62/A170/ZIP during the formation of the aggregates: possible mechanisms and the role in Lewy body formation in Parkinson's disease

Brain research, 2004-06, Vol.1012 (1), p.42-51

2004

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Pramipexole has astrocyte-mediated neuroprotective effects against lactacystin toxicity

Neuroscience letters, 2008-08, Vol.440 (2), p.97-102

2008

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Endogenous catecholamine enhances the dysfunction of unfolded protein response and α-synuclein oligomerization in PC12 cells overexpressing human α-synuclein

Neuroscience research, 2010, Vol.66 (1), p.124-130

2010

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Expression of ubiquitin-binding protein p62 in ubiquitin-immunoreactive intraneuronal inclusions in amyotrophic lateral sclerosis with dementia: analysis of five autopsy cases with broad clinicopathological spectrum

Acta neuropathologica, 2004-04, Vol.107 (4), p.359-364

2004

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L-dopa and dopamine enhance the formation of aggregates under proteasome inhibition in PC12 cells

FEBS letters, 2005-02, Vol.579 (5), p.1197-1202

2005

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Leber's Hereditary Optic Neuropathy with Olivocerebellar Degeneration due to G11778A and T3394C Mutations in the Mitochondrial DNA

Journal of Clinical Neurology, 2012, 8(3), , pp.230-234

2012

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Fluctuating Foville's Syndrome Caused by a Pontine Angioma in a Patient with a Polycystic Kidney

Internal Medicine, 2009, Vol.48(15), pp.1335-1336

2009

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Roles of Microglia in Neurodegenerative Diseases

Parkin controls dopamine utilization in human midbrain dopaminergic neurons derived from induced pluripotent stem cells

Caffeine activates the PI3K/Akt pathway and prevents apoptotic cell death in a Parkinson's disease model of SH-SY5Y cells

Molecular mechanisms underlying the promotion of wound repair by coenzyme Q10: PI3K/Akt signal activation via alterations to cell membrane domains

Parkin Protects Dopaminergic Neurons against Microtubule-depolymerizing Toxins by Attenuating Microtubule-associated Protein Kinase Activation

System xc− in microglia is a novel therapeutic target for post-septic neurological and psychiatric illness

Increased plasma substance P and CGRP levels, and high ACE activity in migraineurs during headache-free periods

Oncogenic role of TYRO3 receptor tyrosine kinase in the progression of pancreatic cancer

Depletion of p62 reduces nuclear inclusions and paradoxically ameliorates disease phenotypes in Huntington's model mice

PI3K is a key molecule in the Nrf2-mediated regulation of antioxidative proteins by hemin in human neuroblastoma cells

TYRO3 promotes chemoresistance via increased LC3 expression in pancreatic cancer

Deficiency of p62/Sequestosome 1 causes hyperphagia due to leptin resistance in the brain

Nicotine enhances the malignant potential of human pancreatic cancer cells via activation of atypical protein kinase C

Dopamine-mediated oxidation of methionine 127 in α-synuclein causes cytotoxicity and oligomerization of α-synuclein

Novel cytoprotective mechanism of anti-parkinsonian drug deprenyl: PI3K and Nrf2-derived induction of antioxidative proteins

Preconditioning by Low Dose LPS Prevents Subsequent LPS-Induced Severe Liver Injury via Nrf2 Activation in Mice

Cytoprotective effect of chlorogenic acid against α-synuclein-related toxicity in catecholaminergic PC12 cells

Rice Bran Dietary Supplementation Improves Neurological Symptoms and Loss of Purkinje Cells in Vitamin E-Deficient Mice

Transcriptional activation of p62/A170/ZIP during the formation of the aggregates: possible mechanisms and the role in Lewy body formation in Parkinson's disease

Pramipexole has astrocyte-mediated neuroprotective effects against lactacystin toxicity

Endogenous catecholamine enhances the dysfunction of unfolded protein response and α-synuclein oligomerization in PC12 cells overexpressing human α-synuclein

Expression of ubiquitin-binding protein p62 in ubiquitin-immunoreactive intraneuronal inclusions in amyotrophic lateral sclerosis with dementia: analysis of five autopsy cases with broad clinicopathological spectrum

L-dopa and dopamine enhance the formation of aggregates under proteasome inhibition in PC12 cells

Leber's Hereditary Optic Neuropathy with Olivocerebellar Degeneration due to G11778A and T3394C Mutations in the Mitochondrial DNA

Fluctuating Foville's Syndrome Caused by a Pontine Angioma in a Patient with a Polycystic Kidney

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