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Potent Therapeutic Activity Against Peritoneal Dissemination and Malignant Ascites by the Novel Anti-Folate Receptor Alpha Antibody KHK2805

Translational oncology, 2017-10, Vol.10 (5), p.707-718

2017

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UCS1025A and B, New Antitumor Antibiotics from the Fungus Acremonium Species

Organic letters, 2002-12, Vol.4 (25), p.4387-4390

2002

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The Discovery and Characterization of K-756, a Novel Wnt/β-Catenin Pathway Inhibitor Targeting Tankyrase

Molecular cancer therapeutics, 2016-07, Vol.15 (7), p.1525-1534

2016

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In vitro and in vivo activity of cefiderocol against Achromobacter spp. and Burkholderia cepacia complex, including carbapenem-non-susceptible isolates

Antimicrobial agents and chemotherapy, 2023-12, Vol.67 (12), p.e0034623-e0034623

2023

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Abstract 2200: Dual pocket binding novel tankyrase inhibitor, K-476, enhances the efficacy of immune checkpoint inhibitor by attracting CD8+ T cells into tumor

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.2200-2200

2020

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1721. In Vitro Activity of Cefiderocol against IMP-Producing Enterobacterales Isolated in Japan

Open forum infectious diseases, 2022-12, Vol.9 (Supplement_2)

2022

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Abstract 2358: KHK2805, a novel ADCC- and CDC-enhanced anti-FOLR1 antibody with AccretaMab® technology, shows a potent anti-tumor activity in combination with pemetrexed

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.2358-2358

2016

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MPC1001, a New Antitumor Antibiotic Produced by Cladorrhinum sp

The Journal of Antibiotics, 2004/08/25, Vol.57(8), pp.532-534

2004

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Abstract 3086: Discovery of a first-in-class TEAD inhibitor which directly inhibits YAP/TAZ-TEAD protein-protein interaction and shows a potent anti-tumor effect in malignant pleural mesothelioma

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.3086-3086

2019

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1066. In Vitro and in Vivo Antimicrobial Activity of Cefiderocol and Comparators against Achromobacter spp

Open forum infectious diseases, 2021-12, Vol.8 (Supplement_1), p.S625-S626

2021

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Abstract B037: The establishment and evaluation of anti-ASC amino acid transporter 2 (ASCT2) antibody as a novel therapeutic antibody for gastric cancer

Molecular cancer therapeutics, 2018-01, Vol.17 (1_Supplement), p.B037-B037

2018

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A Novel Eg5 Inhibitor (LY2523355) Causes Mitotic Arrest and Apoptosis in Cancer Cells and Shows Potent Antitumor Activity in Xenograft Tumor Models

Molecular cancer therapeutics, 2015-11, Vol.14 (11), p.2463-2472

2015

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The discovery and characterization of K‐563, a novel inhibitor of the Keap1/Nrf2 pathway produced by Streptomyces sp

Cancer medicine (Malden, MA), 2019-03, Vol.8 (3), p.1157-1168

2019

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An anti-ASCT2 monoclonal antibody suppresses gastric cancer growth by inducing oxidative stress and antibody dependent cellular toxicity in preclinical models

American journal of cancer research, 2018-01, Vol.8 (8), p.1499-1513

2018

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Abstract A155: Small molecule metabolic inhibitors, compound A and the derivatives specifically inhibit the cell growth of Ewing's sarcoma cells harbor EWS-FLI1 in vitro and in vivo

Molecular cancer therapeutics, 2015-12, Vol.14 (12_Supplement_2), p.A155-A155

2015

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UCS1025A, a Novel Antibiotic Produced by Acremonium sp

The Journal of Antibiotics, 2000/03/25, Vol.53(3), pp.294-296

2000

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The dual pocket binding novel tankyrase inhibitor K-476 enhances the efficacy of immune checkpoint inhibitor by attracting CD8 + T cells to tumors

American journal of cancer research, 2021, Vol.11 (1), p.264-276

2021

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Synthetic studies on mitotic kinesin Eg5 inhibitors: Synthesis and structure–activity relationships of novel 2,4,5-substituted-1,3,4-thiadiazoline derivatives

Bioorganic & medicinal chemistry letters, 2014-08, Vol.24 (16), p.3961-3963

2014

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Abstract C123: A novel anti-FOLR1 antibody developed with AccretaMab® technology, KHK2805, exhibits markedly high ADCC/CDC activity and a tolerable safety profile in preclinical models

Molecular cancer therapeutics, 2015-12, Vol.14 (12_Supplement_2), p.C123-C123

2015

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Abstract C124: A novel anti-FOLR1 antibody developed with AccretaMab® technology, KHK2805, exhibits potent anti-cancer activity against ovarian cancer samples with the FOLR1 expression

Molecular cancer therapeutics, 2015-12, Vol.14 (12_Supplement_2), p.C124-C124

2015

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Abstract C245: Discovery and characterization of a new Wnt/β-catenin pathway inhibitor targeting tankyrase

Molecular cancer therapeutics, 2013-11, Vol.12 (11_Supplement), p.C245-C245

2013

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Chrolactomycin, a Novel Antitumor Antibiotic Produced by Streptomyces sp

The Journal of Antibiotics, 2001/10/25, Vol.54(10), pp.836-839

2001

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Purification and partial characterization of a basic xylanase produced by thermoalkaliphilic Bacillus sp. strain TAR-1

Bioscience, biotechnology, and biochemistry, 2000-04, Vol.64 (4), p.887-890

2000

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Abstract 2715: Discovery and characterization of a highly potent Wnt/ β -catenin pathway inhibitor targeting tankyrase

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.2715-2715

2014

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Ranking the selectivity of PubChem screening hits by activity-based protein profiling: MMP13 as a case study

Bioorganic & medicinal chemistry, 2009-02, Vol.17 (3), p.1101-1108

2009

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Potent Therapeutic Activity Against Peritoneal Dissemination and Malignant Ascites by the Novel Anti-Folate Receptor Alpha Antibody KHK2805

UCS1025A and B, New Antitumor Antibiotics from the Fungus Acremonium Species

The Discovery and Characterization of K-756, a Novel Wnt/β-Catenin Pathway Inhibitor Targeting Tankyrase

In vitro and in vivo activity of cefiderocol against Achromobacter spp. and Burkholderia cepacia complex, including carbapenem-non-susceptible isolates

Abstract 2200: Dual pocket binding novel tankyrase inhibitor, K-476, enhances the efficacy of immune checkpoint inhibitor by attracting CD8+ T cells into tumor

1721. In Vitro Activity of Cefiderocol against IMP-Producing Enterobacterales Isolated in Japan

Abstract 2358: KHK2805, a novel ADCC- and CDC-enhanced anti-FOLR1 antibody with AccretaMab® technology, shows a potent anti-tumor activity in combination with pemetrexed

MPC1001, a New Antitumor Antibiotic Produced by Cladorrhinum sp

Abstract 3086: Discovery of a first-in-class TEAD inhibitor which directly inhibits YAP/TAZ-TEAD protein-protein interaction and shows a potent anti-tumor effect in malignant pleural mesothelioma

1066. In Vitro and in Vivo Antimicrobial Activity of Cefiderocol and Comparators against Achromobacter spp

Abstract B037: The establishment and evaluation of anti-ASC amino acid transporter 2 (ASCT2) antibody as a novel therapeutic antibody for gastric cancer

A Novel Eg5 Inhibitor (LY2523355) Causes Mitotic Arrest and Apoptosis in Cancer Cells and Shows Potent Antitumor Activity in Xenograft Tumor Models

The discovery and characterization of K‐563, a novel inhibitor of the Keap1/Nrf2 pathway produced by Streptomyces sp

An anti-ASCT2 monoclonal antibody suppresses gastric cancer growth by inducing oxidative stress and antibody dependent cellular toxicity in preclinical models

Abstract A155: Small molecule metabolic inhibitors, compound A and the derivatives specifically inhibit the cell growth of Ewing's sarcoma cells harbor EWS-FLI1 in vitro and in vivo

UCS1025A, a Novel Antibiotic Produced by Acremonium sp

The dual pocket binding novel tankyrase inhibitor K-476 enhances the efficacy of immune checkpoint inhibitor by attracting CD8 + T cells to tumors

Synthetic studies on mitotic kinesin Eg5 inhibitors: Synthesis and structure–activity relationships of novel 2,4,5-substituted-1,3,4-thiadiazoline derivatives

Abstract C123: A novel anti-FOLR1 antibody developed with AccretaMab® technology, KHK2805, exhibits markedly high ADCC/CDC activity and a tolerable safety profile in preclinical models

Abstract C124: A novel anti-FOLR1 antibody developed with AccretaMab® technology, KHK2805, exhibits potent anti-cancer activity against ovarian cancer samples with the FOLR1 expression

Abstract C245: Discovery and characterization of a new Wnt/β-catenin pathway inhibitor targeting tankyrase

Chrolactomycin, a Novel Antitumor Antibiotic Produced by Streptomyces sp

Purification and partial characterization of a basic xylanase produced by thermoalkaliphilic Bacillus sp. strain TAR-1

Abstract 2715: Discovery and characterization of a highly potent Wnt/ β -catenin pathway inhibitor targeting tankyrase

Ranking the selectivity of PubChem screening hits by activity-based protein profiling: MMP13 as a case study

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