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Non-electrophilic TRPA1 agonists, menthol, carvacrol and clotrimazole, open epithelial tight junctions via TRPA1 activation

Journal of biochemistry (Tokyo), 2020-10, Vol.168 (4), p.407

2020

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Transient receptor potential V4 channel stimulation induces reversible epithelial cell permeability in MDCK cell monolayers

FEBS letters, 2019-08, Vol.593 (16), p.2250-2260

2019

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The reversible increase in tight junction permeability induced by capsaicin is mediated via cofilin-actin cytoskeletal dynamics and decreased level of occludin

PloS one, 2013-11, Vol.8 (11), p.e79954

2013

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MA026, an anti-hepatitis C virus compound, opens tight junctions of the epithelial cell membrane

Journal of antibiotics, 2017-05, Vol.70 (5), p.691-694

2017

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Structural Revision of Natural Cyclic Depsipeptide MA026 Established by Total Synthesis and Biosynthetic Gene Cluster Analysis

Angewandte Chemie (International ed.), 2021-04, Vol.60 (16), p.8792-8797

International ed. in English, 2021

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Construction of Multidrug-Sensitive Yeast with High Sporulation Efficiency

Bioscience, biotechnology, and biochemistry, 2011, Vol.75 (8), p.1588-1593

2011

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Total Synthesis and Biological Evaluation of Irciniastatin A (a.k.a. Psymberin) and Irciniastatin B

Journal of organic chemistry, 2015-12, Vol.80 (24), p.12333-12350

2015

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Cofilin mediates tight-junction opening by redistributing actin and tight-junction proteins

Biochemical and biophysical research communications, 2008-12, Vol.377 (3), p.921-925

2008

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Vicenistatin induces early endosome-derived vacuole formation in mammalian cells

Bioscience, biotechnology, and biochemistry, 2016-05, Vol.80 (5), p.902-910

2016

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Dual Inhibition of γ-Tubulin and Plk1 Induces Mitotic Cell Death

Frontiers in pharmacology, 2021-01, Vol.11, p.620185-620185

2021

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Protective effects of Nitraria retusa extract and its constituent isorhamnetin against amyloid β-induced cytotoxicity and amyloid β aggregation

Bioscience, biotechnology, and biochemistry, 2015-09, Vol.79 (9), p.1548-1551

2015

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Construction of a genetic analysis-available multidrug sensitive yeast strain by disruption of the drug efflux system and conditional repression of the membrane barrier system

The Journal of General and Applied Microbiology, 2014, Vol.60(4), pp.160-162

2014

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Increased CD112 expression in methylcholanthrene-induced tumors in CD155-deficient mice

PloS one, 2014-11, Vol.9 (11), p.e112415-e112415

2014

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Trastuzumab and Pertuzumab Produce Changes in Morphology and Estrogen Receptor Signaling in Ovarian Cancer Xenografts Revealing New Treatment Strategies

Clinical cancer research, 2011-07, Vol.17 (13), p.4451-4461

2011

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Terpendole E and its Derivative Inhibit STLC- and GSK-1-Resistant Eg5

Chembiochem : a European journal of chemical biology, 2014-05, Vol.15 (7), p.934-938

2014

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Modulation of HER3 Is a Marker of Dynamic Cell Signaling in Ovarian Cancer: Implications for Pertuzumab Sensitivity

Molecular cancer research, 2009-09, Vol.7 (9), p.1563-1571

2009

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Capsaicin indirectly regulates TRPA1 via the arachidonic acid cascade, resulting in TJ opening

Bioscience, biotechnology, and biochemistry, 2023-12, Vol.88 (1), p.44-52

2023

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Synthesis-Based Approach toward Direct Sandwich Immunoassay for Ciguatoxin CTX3C

Journal of the American Chemical Society, 2003-06, Vol.125 (25), p.7608-7612

2003

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Pertuzumab for the treatment of ovarian cancer

Expert opinion on biological therapy, 2010-07, Vol.10 (7), p.1113-1120

2010

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Capsaicin induces cofilin dephosphorylation in human intestinal cells: The triggering role of cofilin in tight-junction signaling

Biochemical and biophysical research communications, 2007-04, Vol.355 (2), p.520-525

2007

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Structure‐Activity Relationships of Terpendole E and Its Natural Derivatives

ChemistrySelect (Weinheim), 2017-02, Vol.2 (4), p.1533-1536

2017

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RSK4 confers paclitaxel resistance to ovarian cancer cells, which is resensitized by its inhibitor BI-D1870

Biochemical and biophysical research communications, 2023-10, Vol.679, p.23-30

2023

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Convergent synthesis of the trans-fused 6-n-6-6 (n = 7–10) tetracyclic ether system based on a ring-closing metathesis reaction

Chemical communications (Cambridge, England), 1998 (9), p.1041-1042

1998

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Structure–activity relationships of epolactaene derivatives: structural requirements for inhibition of Hsp60 chaperone activity

Bioorganic & medicinal chemistry letters, 2004-09, Vol.14 (17), p.4425-4429

2004

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A novel translation inhibitor, mersicarpine, inhibits S-phase progression and induces apoptosis in HL60 cells

Bioscience, biotechnology, and biochemistry, 2021-01, Vol.85 (1), p.92-96

2021

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Non-electrophilic TRPA1 agonists, menthol, carvacrol and clotrimazole, open epithelial tight junctions via TRPA1 activation

Transient receptor potential V4 channel stimulation induces reversible epithelial cell permeability in MDCK cell monolayers

The reversible increase in tight junction permeability induced by capsaicin is mediated via cofilin-actin cytoskeletal dynamics and decreased level of occludin

MA026, an anti-hepatitis C virus compound, opens tight junctions of the epithelial cell membrane

Structural Revision of Natural Cyclic Depsipeptide MA026 Established by Total Synthesis and Biosynthetic Gene Cluster Analysis

Construction of Multidrug-Sensitive Yeast with High Sporulation Efficiency

Total Synthesis and Biological Evaluation of Irciniastatin A (a.k.a. Psymberin) and Irciniastatin B

Cofilin mediates tight-junction opening by redistributing actin and tight-junction proteins

Vicenistatin induces early endosome-derived vacuole formation in mammalian cells

Dual Inhibition of γ-Tubulin and Plk1 Induces Mitotic Cell Death

Protective effects of Nitraria retusa extract and its constituent isorhamnetin against amyloid β-induced cytotoxicity and amyloid β aggregation

Construction of a genetic analysis-available multidrug sensitive yeast strain by disruption of the drug efflux system and conditional repression of the membrane barrier system

Increased CD112 expression in methylcholanthrene-induced tumors in CD155-deficient mice

Trastuzumab and Pertuzumab Produce Changes in Morphology and Estrogen Receptor Signaling in Ovarian Cancer Xenografts Revealing New Treatment Strategies

Terpendole E and its Derivative Inhibit STLC- and GSK-1-Resistant Eg5

Modulation of HER3 Is a Marker of Dynamic Cell Signaling in Ovarian Cancer: Implications for Pertuzumab Sensitivity

Capsaicin indirectly regulates TRPA1 via the arachidonic acid cascade, resulting in TJ opening

Synthesis-Based Approach toward Direct Sandwich Immunoassay for Ciguatoxin CTX3C

Pertuzumab for the treatment of ovarian cancer

Capsaicin induces cofilin dephosphorylation in human intestinal cells: The triggering role of cofilin in tight-junction signaling

Structure‐Activity Relationships of Terpendole E and Its Natural Derivatives

RSK4 confers paclitaxel resistance to ovarian cancer cells, which is resensitized by its inhibitor BI-D1870

Convergent synthesis of the trans-fused 6-n-6-6 (n = 7–10) tetracyclic ether system based on a ring-closing metathesis reaction

Structure–activity relationships of epolactaene derivatives: structural requirements for inhibition of Hsp60 chaperone activity

A novel translation inhibitor, mersicarpine, inhibits S-phase progression and induces apoptosis in HL60 cells

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