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Mechanisms of Inhibition of Aldehyde Dehydrogenase by Nitroxyl, the Active Metabolite of the Alcohol Deterrent Agent Cyanamide

Biochemical pharmacology, 1998-06, Vol.55 (12), p.2007-2015

1998

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Prevention of naphthalene-induced pulmonary toxicity by glutathione prodrugs: Roles for glutathione depletion in adduct formation and cell injury

Journal of biochemical and molecular toxicology, 2005-01, Vol.19 (1), p.42-51

2005

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Evidence for nitroxyl in the catalase-mediated bioactivation of the alcohol deterrent agent cyanamide

Journal of medicinal chemistry, 1990-12, Vol.33 (12), p.3120-3122

1990

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Reaction between S-Nitrosothiols and Thiols: Generation of Nitroxyl (HNO) and Subsequent Chemistry

Biochemistry (Easton), 1998-04, Vol.37 (16), p.5362-5371

1998

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N-Terminal Dipeptides of d(−)-Penicillamine as Sequestration Agents for Acetaldehyde

Journal of medicinal chemistry, 2000-03, Vol.43 (5), p.1029-1033

2000

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Diethylcarbamoylating/Nitroxylating Agents as Dual Action Inhibitors of Aldehyde Dehydrogenase: A Disulfiram−Cyanamide Merger

Journal of medicinal chemistry, 1999-10, Vol.42 (20), p.4016-4020

1999

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Prodrugs of Nitroxyl and Nitrosobenzene as Cascade Latentiated Inhibitors of Aldehyde Dehydrogenase

Journal of medicinal chemistry, 1998-07, Vol.41 (15), p.2903-2909

1998

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Inhibition of human class 3 aldehyde dehydrogenase, and sensitization of tumor cells that express significant amounts of this enzyme to oxazaphosphorines, by chlorpropamide analogues

Biochemical pharmacology, 1998-02, Vol.55 (4), p.465-474

1998

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Mechanism for the inhibition of aldehyde dehydrogenase by nitric oxide

Alcohol (Fayetteville, N.Y.), 1997-03, Vol.14 (2), p.181-189

1997

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Prodrugs of nitroxyl as inhibitors of aldehyde dehydrogenase

Journal of medicinal chemistry, 1992-10, Vol.35 (20), p.3648-3652

1992

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N,O-Diacylated-N-hydroxyarylsulfonamides: Nitroxyl precursors with potent smooth muscle relaxant properties

Biochemical and biophysical research communications, 1992-09, Vol.187 (3), p.1367-1373

1992

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Prevention of acetaminophen- and naphthalene-induced cataract and glutathione loss by CySSME

Investigative ophthalmology & visual science, 1996-04, Vol.37 (5), p.923-929

1996

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Prevention of Naphthalene-Induced Cataract and Hepatic Glutathione Loss by the L-Cysteine Prodrugs, MTCA and PTCA

Experimental eye research, 1996-04, Vol.62 (4), p.433-442

1996

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Maintenance of hepatic glutathione homeostasis and prevention of acetaminophen-induced cataract in mice by L-cysteine prodrugs

Biochemical pharmacology, 1996-05, Vol.51 (9), p.1111-1116

1996

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Involvement of nitroxyl (HNO) in the cyanamide-induced vasorelaxation of rabbit aorta

Biochemical pharmacology, 1994-03, Vol.47 (5), p.922-924

1994

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Novel Prodrugs of Cyanamide That Inhibit Aldehyde Dehydrogenase in Vivo

Journal of medicinal chemistry, 1997-06, Vol.40 (12), p.1870-1875

1997

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Nitrosyl cyanide, a putative metabolic oxidation product of the alcohol-deterrent agent cyanamide

Biochemical pharmacology, 1996-07, Vol.52 (1), p.141-147

1996

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Chemical approaches toward generation of nitroxyl

Methods in enzymology, 1999, Vol.301, p.211-220

1999

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Reaction of Nitroxyl, an Aldehyde Dehydrogenase Inhibitor, with N-Acetyl-L-Cysteine

Alcohol, 2000, Vol.20 (1), p.55-59

2000

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Augmentation of Human and Rat Lenticular Glutathione in Vitro by Prodrugs of γ-l-Glutamyl-l-cysteine

Journal of medicinal chemistry, 1996-04, Vol.39 (8), p.1676-1681

1996

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Reaction of Nitric Oxide with the Free Sulfhydryl Group of Human Serum Albumin Yields a Sulfenic Acid and Nitrous Oxide

Biochemistry (Easton), 1995-09, Vol.34 (36), p.11494-11499

1995

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An N-hydroxylated derivative of cyanamide that inhibits yeast aldehyde dehydrogenase

Alcohol (Fayetteville, N.Y.), 1992-09, Vol.9 (5), p.349-353

1992

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Nitroxyl analogs as inhibitors of aldehyde dehydrogenase: C-nitroso compounds

Biochemical pharmacology, 1993-05, Vol.45 (10), p.2129-2134

1993

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2-Substituted thiazolidine-4(R)-carboxylic acids as prodrugs of L-cysteine. Protection of mice against acetaminophen hepatotoxicity

Journal of medicinal chemistry, 1984-05, Vol.27 (5), p.591-596

1984

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Glutathione monoethyl ester protects against glutathione deficiencies due to aging and acetaminophen in mice

Mechanisms of ageing and development, 2000-12, Vol.120 (1), p.127-139

2000

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Mechanisms of Inhibition of Aldehyde Dehydrogenase by Nitroxyl, the Active Metabolite of the Alcohol Deterrent Agent Cyanamide

Prevention of naphthalene-induced pulmonary toxicity by glutathione prodrugs: Roles for glutathione depletion in adduct formation and cell injury

Evidence for nitroxyl in the catalase-mediated bioactivation of the alcohol deterrent agent cyanamide

Reaction between S-Nitrosothiols and Thiols: Generation of Nitroxyl (HNO) and Subsequent Chemistry

N-Terminal Dipeptides of d(−)-Penicillamine as Sequestration Agents for Acetaldehyde

Diethylcarbamoylating/Nitroxylating Agents as Dual Action Inhibitors of Aldehyde Dehydrogenase: A Disulfiram−Cyanamide Merger

Prodrugs of Nitroxyl and Nitrosobenzene as Cascade Latentiated Inhibitors of Aldehyde Dehydrogenase

Inhibition of human class 3 aldehyde dehydrogenase, and sensitization of tumor cells that express significant amounts of this enzyme to oxazaphosphorines, by chlorpropamide analogues

Mechanism for the inhibition of aldehyde dehydrogenase by nitric oxide

Prodrugs of nitroxyl as inhibitors of aldehyde dehydrogenase

N,O-Diacylated-N-hydroxyarylsulfonamides: Nitroxyl precursors with potent smooth muscle relaxant properties

Prevention of acetaminophen- and naphthalene-induced cataract and glutathione loss by CySSME

Prevention of Naphthalene-Induced Cataract and Hepatic Glutathione Loss by the L-Cysteine Prodrugs, MTCA and PTCA

Maintenance of hepatic glutathione homeostasis and prevention of acetaminophen-induced cataract in mice by L-cysteine prodrugs

Involvement of nitroxyl (HNO) in the cyanamide-induced vasorelaxation of rabbit aorta

Novel Prodrugs of Cyanamide That Inhibit Aldehyde Dehydrogenase in Vivo

Nitrosyl cyanide, a putative metabolic oxidation product of the alcohol-deterrent agent cyanamide

Chemical approaches toward generation of nitroxyl

Reaction of Nitroxyl, an Aldehyde Dehydrogenase Inhibitor, with N-Acetyl-L-Cysteine

Augmentation of Human and Rat Lenticular Glutathione in Vitro by Prodrugs of γ-l-Glutamyl-l-cysteine

Reaction of Nitric Oxide with the Free Sulfhydryl Group of Human Serum Albumin Yields a Sulfenic Acid and Nitrous Oxide

An N-hydroxylated derivative of cyanamide that inhibits yeast aldehyde dehydrogenase

Nitroxyl analogs as inhibitors of aldehyde dehydrogenase: C-nitroso compounds

2-Substituted thiazolidine-4(R)-carboxylic acids as prodrugs of L-cysteine. Protection of mice against acetaminophen hepatotoxicity

Glutathione monoethyl ester protects against glutathione deficiencies due to aging and acetaminophen in mice

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