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The ADAM gene family: surface proteins with adhesion and protease activity

Trends in Genetics, 2000-02, Vol.16 (2), p.83-87

2000

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Fertilization Defects in Sperm from Mice Lacking Fertilin β

Science (American Association for the Advancement of Science), 1998-09, Vol.281 (5384), p.1857-1859

1998

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Why did the sperm cross the cumulus? To get to the oocyte. Functions of the sperm surface proteins PH-20 and fertilin in arriving at, and fusing with, the egg

Biology of reproduction, 1997-02, Vol.56 (2), p.320-327

1997

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ADAM, a novel family of membrane proteins containing A Disintegrin And Metalloprotease domain: multipotential functions in cell-cell and cell-matrix interactions

The Journal of cell biology, 1995-10, Vol.131 (2), p.275-278

1995

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A Hyaluronidase Activity of the Sperm Plasma Membrane Protein PH-20 Enables Sperm to Penetrate the Cumulus Cell Layer Surrounding the Egg

The Journal of cell biology, 1994-06, Vol.125 (5), p.1157-1163

1994

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Molecular Mechanisms of Sperm-Egg Membrane Binding and Fusion in Mammals

Developmental Biology, 1993-07, Vol.158 (1), p.35-45

Myles, Diana G.

1993

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A potential fusion peptide and an integrin ligand domain in a protein active in sperm-egg fusion

Nature (London), 1992-03, Vol.356 (6366), p.248-252

1992

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Sperm surface protein PH-20 is bifunctional: one activity is a hyaluronidase and a second, distinct activity is required in secondary sperm-zona binding

Biology of reproduction, 1996-07, Vol.55 (1), p.80-86

1996

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Identification of a Binding Site in the Disintegrin Domain of Fertilin Required for Sperm-Egg Fusion

Proceedings of the National Academy of Sciences - PNAS, 1994-05, Vol.91 (10), p.4195-4198

1994

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The precursor region of a protein active in sperm-egg fusion contains a metalloprotease and a disintegrin domain: structural, functional, and evolutionary implications

Proceedings of the National Academy of Sciences - PNAS, 1993-11, Vol.90 (22), p.10783-10787

1993

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Mechanism of infertility in male guinea pigs immunized with sperm PH-20

Biology of reproduction, 1997-05, Vol.56 (5), p.1133-1141

1997

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Analysis of Loss of Adhesive Function in Sperm Lacking Cyritestin or Fertilin β

Developmental biology, 2001-05, Vol.233 (1), p.204-213

2001

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Molecular Cloning of the Human and Monkey Sperm Surface Protein PH-20

Proceedings of the National Academy of Sciences - PNAS, 1993-11, Vol.90 (21), p.10071-10075

1993

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Location of the PH-20 protein on acrosome-intact and acrosome-reacted spermatozoa of cynomolgus macaques

Biology of reproduction, 1995-01, Vol.52 (1), p.105-114

1995

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Structural relationship of sperm soluble hyaluronidase to the sperm membrane protein PH-20

Biology of reproduction, 1996-06, Vol.54 (6), p.1343-1349

1996

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A Role for the Disintegrin Domain of Cyritestin, a Sperm Surface Protein Belonging to the ADAM Family, in Mouse Sperm-Egg Plasma Membrane Adhesion and Fusion

The Journal of cell biology, 1997-04, Vol.137 (1), p.105-112

1997

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A Role for the Migrating Sperm Surface Antigen PH-20 in Guinea Pig Sperm Binding to the Egg Zona Pellucida

The Journal of cell biology, 1985-12, Vol.101 (6), p.2239-2244

1985

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cDNA Cloning Reveals the Molecular Structure of a Sperm Surface Protein, PH-20, Involved in Sperm-Egg Adhesion and the Wide Distribution of Its Gene among Mammals

The Journal of cell biology, 1990-12, Vol.111 (6), p.2939-2949

1990

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Residues SFQ (173-175) in the large extracellular loop of CD9 are required for gamete fusion

Development (Cambridge), 2002-04, Vol.129 (8), p.1995-2002

2002

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Proteolytic Processing of a Protein Involved in Sperm-Egg Fusion Correlates with Acquisition of Fertilization Competence

The Journal of cell biology, 1990-07, Vol.111 (1), p.69-78

1990

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Localized Surface Antigens of Guinea Pig Sperm Migrate to New Regions Prior to Fertilization

The Journal of cell biology, 1984-11, Vol.99 (5), p.1634-1641

1984

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Reversible contraceptive effect of PH-20 immunization in male guinea pigs

Biology of reproduction, 1997-05, Vol.56 (5), p.1142-1146

1997

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Defects in Secretory Pathway Trafficking During Sperm Development in Adam2 Knockout Mice

Biology of reproduction, 2005-11, Vol.73 (5), p.1032-1038

2005

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Evidence That Proteolysis of the Surface Is an Initial Step in the Mechanism of Formation of Sperm Cell Surface Domains

The Journal of cell biology, 1990-11, Vol.111 (5), p.1839-1847

1990

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Analysis of Mouse Fertilin in Wild-Type and Fertilin β−/− Sperm: Evidence for C-terminal Modification, α/β Dimerization, and Lack of Essential Role of Fertilin α in Sperm–Egg Fusion

Developmental biology, 2000-06, Vol.222 (2), p.289-295

2000

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The ADAM gene family: surface proteins with adhesion and protease activity

Fertilization Defects in Sperm from Mice Lacking Fertilin β

Why did the sperm cross the cumulus? To get to the oocyte. Functions of the sperm surface proteins PH-20 and fertilin in arriving at, and fusing with, the egg

ADAM, a novel family of membrane proteins containing A Disintegrin And Metalloprotease domain: multipotential functions in cell-cell and cell-matrix interactions

A Hyaluronidase Activity of the Sperm Plasma Membrane Protein PH-20 Enables Sperm to Penetrate the Cumulus Cell Layer Surrounding the Egg

Molecular Mechanisms of Sperm-Egg Membrane Binding and Fusion in Mammals

A potential fusion peptide and an integrin ligand domain in a protein active in sperm-egg fusion

Sperm surface protein PH-20 is bifunctional: one activity is a hyaluronidase and a second, distinct activity is required in secondary sperm-zona binding

Identification of a Binding Site in the Disintegrin Domain of Fertilin Required for Sperm-Egg Fusion

The precursor region of a protein active in sperm-egg fusion contains a metalloprotease and a disintegrin domain: structural, functional, and evolutionary implications

Mechanism of infertility in male guinea pigs immunized with sperm PH-20

Analysis of Loss of Adhesive Function in Sperm Lacking Cyritestin or Fertilin β

Molecular Cloning of the Human and Monkey Sperm Surface Protein PH-20

Location of the PH-20 protein on acrosome-intact and acrosome-reacted spermatozoa of cynomolgus macaques

Structural relationship of sperm soluble hyaluronidase to the sperm membrane protein PH-20

A Role for the Disintegrin Domain of Cyritestin, a Sperm Surface Protein Belonging to the ADAM Family, in Mouse Sperm-Egg Plasma Membrane Adhesion and Fusion

A Role for the Migrating Sperm Surface Antigen PH-20 in Guinea Pig Sperm Binding to the Egg Zona Pellucida

cDNA Cloning Reveals the Molecular Structure of a Sperm Surface Protein, PH-20, Involved in Sperm-Egg Adhesion and the Wide Distribution of Its Gene among Mammals

Residues SFQ (173-175) in the large extracellular loop of CD9 are required for gamete fusion

Proteolytic Processing of a Protein Involved in Sperm-Egg Fusion Correlates with Acquisition of Fertilization Competence

Localized Surface Antigens of Guinea Pig Sperm Migrate to New Regions Prior to Fertilization

Reversible contraceptive effect of PH-20 immunization in male guinea pigs

Defects in Secretory Pathway Trafficking During Sperm Development in Adam2 Knockout Mice

Evidence That Proteolysis of the Surface Is an Initial Step in the Mechanism of Formation of Sperm Cell Surface Domains

Analysis of Mouse Fertilin in Wild-Type and Fertilin β−/− Sperm: Evidence for C-terminal Modification, α/β Dimerization, and Lack of Essential Role of Fertilin α in Sperm–Egg Fusion

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