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Use of adeno-associated virus as a general transduction vector for mammalian cells

Current topics in microbiology and immunology, 1992, Vol.158, p.97

Muzyczka, N

1992

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Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield

Gene therapy, 1999-06, Vol.6 (6), p.973-985

1999

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Observed incidence of tumorigenesis in long-term rodent studies of rAAV vectors

Gene therapy, 2001-09, Vol.8 (17), p.1343-1346

2001

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Mutational Analysis of the Adeno-Associated Virus Type 2 (AAV2) Capsid Gene and Construction of AAV2 Vectors with Altered Tropism

Journal of Virology, 2000-09, Vol.74 (18), p.8635-8647

2000

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A "humanized" green fluorescent protein cDNA adapted for high-level expression in mammalian cells

Journal of Virology, 1996-07, Vol.70 (7), p.4646-4654

1996

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Targeting recombinant adeno-associated virus vectors to enhance gene transfer to pancreatic islets and liver

Gene therapy, 2003-09, Vol.10 (18), p.1551-1558

2003

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Mechanism of Rep-Mediated Adeno-Associated Virus Origin Nicking

Journal of Virology, 2000-09, Vol.74 (17), p.7762-7771

2000

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The adeno-associated virus (AAV) Rep protein acts as both a repressor and an activator to regulate AAV transcription during a productive infection

Journal of Virology, 1997-02, Vol.71 (2), p.1079-1088

1997

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Efficient transduction of green fluorescent protein in spinal cord neurons using adeno-associated virus vectors containing cell type-specific promoters

Gene therapy, 1997, Vol.4 (1), p.16-24

1997

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Central leptin gene therapy suppresses body weight gain, adiposity and serum insulin without affecting food consumption in normal rats: a long-term study

Regulatory peptides, 2001-06, Vol.99 (2), p.69-77

2001

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High-titer recombinant adeno-associated virus production utilizing a recombinant herpes simplex virus type I vector expressing AAV-2 rep and cap

Gene therapy, 1999-06, Vol.6 (6), p.986-993

1999

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Recombinant AAV Viral Vectors Pseudotyped with Viral Capsids from Serotypes 1, 2, and 5 Display Differential Efficiency and Cell Tropism after Delivery to Different Regions of the Central Nervous System

Molecular therapy, 2004-08, Vol.10 (2), p.302-317

2004

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Sequence requirements for binding of Rep68 to the adeno-associated virus terminal repeats

Journal of Virology, 1996-03, Vol.70 (3), p.1542-1553

1996

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Nigrostriatal α-Synucleinopathy Induced by Viral Vector-Mediated Overexpression of Human α-Synuclein: A New Primate Model of Parkinson's Disease

Proceedings of the National Academy of Sciences - PNAS, 2003-03, Vol.100 (5), p.2884-2889

2003

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Site-Specific Integration by Adeno-Associated Virus

Proceedings of the National Academy of Sciences - PNAS, 1990-03, Vol.87 (6), p.2211-2215

1990

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Development of in vivo gene therapy for hearing disorders: introduction of adeno-associated virus into the cochlea of the guinea pig

Gene therapy, 1996-07, Vol.3 (7), p.588

1996

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The cellular transcription factor SP1 and an unknown cellular protein are required to mediate Rep protein activation of the adeno-associated virus p19 promoter

Journal of Virology, 1997-03, Vol.71 (3), p.1747-1756

1997

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Identification of Amino Acid Residues in the Capsid Proteins of Adeno-Associated Virus Type 2 That Contribute to Heparan Sulfate Proteoglycan Binding

Journal of Virology, 2003-06, Vol.77 (12), p.6995-7006

2003

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Recombinant adeno-associated virus type 2 replication and packaging is entirely supported by a herpes simplex virus type 1 amplicon expressing Rep and Cap

Journal of Virology, 1997-11, Vol.71 (11), p.8780-8789

1997

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Adeno-associated virus (AAV) vectors: will they work?

The Journal of clinical investigation, 1994-10, Vol.94 (4), p.1351-1351

Muzyczka, N

1994

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Differential Modulation of Energy Balance by Leptin, Ciliary Neurotrophic Factor, and Leukemia Inhibitory Factor Gene Delivery: Microarray Deoxyribonucleic Acid-Chip Analysis of Gene Expression

Endocrinology (Philadelphia), 2004-04, Vol.145 (4), p.2035-2045

2004

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Long-term in vivo cochlear transgene expression mediated by recombinant adeno-associated virus

Gene therapy, 1998-02, Vol.5 (2), p.277-281

1998

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Parkinson-Like Neurodegeneration Induced by Targeted Overexpression of alpha -Synuclein in the Nigrostriatal System

The Journal of neuroscience, 2002-04, Vol.22 (7), p.2780-2791

2002

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Circulating Anti-Wild-Type Adeno-Associated Virus Type 2 (AAV2) Antibodies Inhibit Recombinant AAV2 (rAAV2)-Mediated, but Not rAAV5-Mediated, Gene Transfer in the Brain

Journal of Virology, 2004-06, Vol.78 (12), p.6344-6359

2004

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Tyrosine-phosphorylation of AAV2 vectors and its consequences on viral intracellular trafficking and transgene expression

Virology (New York, N.Y.), 2008-11, Vol.381 (2), p.194-202

2008

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Use of adeno-associated virus as a general transduction vector for mammalian cells

Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield

Observed incidence of tumorigenesis in long-term rodent studies of rAAV vectors

Mutational Analysis of the Adeno-Associated Virus Type 2 (AAV2) Capsid Gene and Construction of AAV2 Vectors with Altered Tropism

A "humanized" green fluorescent protein cDNA adapted for high-level expression in mammalian cells

Targeting recombinant adeno-associated virus vectors to enhance gene transfer to pancreatic islets and liver

Mechanism of Rep-Mediated Adeno-Associated Virus Origin Nicking

The adeno-associated virus (AAV) Rep protein acts as both a repressor and an activator to regulate AAV transcription during a productive infection

Efficient transduction of green fluorescent protein in spinal cord neurons using adeno-associated virus vectors containing cell type-specific promoters

Central leptin gene therapy suppresses body weight gain, adiposity and serum insulin without affecting food consumption in normal rats: a long-term study

High-titer recombinant adeno-associated virus production utilizing a recombinant herpes simplex virus type I vector expressing AAV-2 rep and cap

Recombinant AAV Viral Vectors Pseudotyped with Viral Capsids from Serotypes 1, 2, and 5 Display Differential Efficiency and Cell Tropism after Delivery to Different Regions of the Central Nervous System

Sequence requirements for binding of Rep68 to the adeno-associated virus terminal repeats

Nigrostriatal α-Synucleinopathy Induced by Viral Vector-Mediated Overexpression of Human α-Synuclein: A New Primate Model of Parkinson's Disease

Site-Specific Integration by Adeno-Associated Virus

Development of in vivo gene therapy for hearing disorders: introduction of adeno-associated virus into the cochlea of the guinea pig

The cellular transcription factor SP1 and an unknown cellular protein are required to mediate Rep protein activation of the adeno-associated virus p19 promoter

Identification of Amino Acid Residues in the Capsid Proteins of Adeno-Associated Virus Type 2 That Contribute to Heparan Sulfate Proteoglycan Binding

Recombinant adeno-associated virus type 2 replication and packaging is entirely supported by a herpes simplex virus type 1 amplicon expressing Rep and Cap

Adeno-associated virus (AAV) vectors: will they work?

Differential Modulation of Energy Balance by Leptin, Ciliary Neurotrophic Factor, and Leukemia Inhibitory Factor Gene Delivery: Microarray Deoxyribonucleic Acid-Chip Analysis of Gene Expression

Long-term in vivo cochlear transgene expression mediated by recombinant adeno-associated virus

Parkinson-Like Neurodegeneration Induced by Targeted Overexpression of alpha -Synuclein in the Nigrostriatal System

Circulating Anti-Wild-Type Adeno-Associated Virus Type 2 (AAV2) Antibodies Inhibit Recombinant AAV2 (rAAV2)-Mediated, but Not rAAV5-Mediated, Gene Transfer in the Brain

Tyrosine-phosphorylation of AAV2 vectors and its consequences on viral intracellular trafficking and transgene expression

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