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Targeting melanocortin receptors: an approach to treat weight disorders and sexual dysfunction

Nature reviews. Drug discovery, 2008-04, Vol.7 (4), p.307-323

2008

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A look inside HIV resistance through retroviral protease interaction maps

PLoS computational biology, 2007-03, Vol.3 (3), p.e48-e48

2007

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Selective Antagonist for the Melanocortin 4 Receptor (HS014) Increases Food Intake in Free-Feeding Rats

Biochemical and biophysical research communications, 1998-04, Vol.245 (1), p.90-93

1998

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Proteochemometric Mapping of the Interaction of Organic Compounds with Melanocortin Receptor Subtypes

Molecular pharmacology, 2005-01, Vol.67 (1), p.50-59

2005

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Design and synthesis of a library of tertiary amides: Evaluation as mimetics of the melanocortins’ active core

Bioorganic & medicinal chemistry, 2007-09, Vol.15 (17), p.5787-5810

2007

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Oligomerization of indole derivatives with incorporation of thiols

Molecules (Basel, Switzerland), 2008-08, Vol.13 (8), p.1846-1863

2008

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Phage Display Selection on Whole Cells Yields a Peptide Specific for Melanocortin Receptor 1

The Journal of biological chemistry, 1997-10, Vol.272 (44), p.27943-27948

1997

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Long term orexigenic effect of a novel melanocortin 4 receptor selective antagonist

British journal of pharmacology, 1999-01, Vol.126 (1), p.27-34

1999

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2-(p-Hydroxybenzyl)indoles - Side Products Formed Upon Cleavage of Indole Derivatives from Carboxylated Wang Polymer - an NMR Study

Molecules (Basel, Switzerland), 2003-10, Vol.8 (10), p.728-734

2003

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Libiguins A and B: novel phragmalin limonoids isolated from Neobeguea mahafalensis causing profound enhancement of sexual activity

Planta medica, 2014-03, Vol.80 (4), p.306-314

2014

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Probing the substrate specificity of the dengue virus type 2 NS3 serine protease by using internally quenched fluorescent peptides

Biochemical journal, 2006-07, Vol.397 (1), p.203-211

2006

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Discovery of novel melanocortin 4 receptor selective MSH analogues

British journal of pharmacology, 2009-02, Vol.124 (1), p.75-82

2009

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Discovery of a Novel Superpotent and Selective Melanocortin-4 Receptor Antagonist (HS024): Evaluation in Vitro and in VivoThis work was supported by grants from the Swedish Medical Research Council (04X-05957), the Swedish Society for Medical Research, and the Estonian Science Foundation (Grant 3267); the Ants ja Maria Silvere ning Sigfried Panti Mälestusstipendium Foundation (to A.K.); and the Swedish Institute (to I.M.)

Endocrinology (Philadelphia), 1998-12, Vol.139 (12), p.5006-5014

1998

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The MC4 receptor mediates α-MSH induced release of nucleus accumbens dopamine

Neuroreport, 2001-07, Vol.12 (10), p.2155-2158

2001

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QSAR and Proteo-chemometric Analysis of the Interaction of a Series of Organic Compounds with Melanocortin Receptor Subtypes

Journal of medicinal chemistry, 2003-06, Vol.46 (13), p.2572-2579

2003

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Kinetic evidence for tandemly arranged ligand binding sites in melanocortin 4 receptor complexes

Neurochemistry international, 2006-10, Vol.49 (5), p.533-542

2006

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New Substituted Piperazines as Ligands for Melanocortin Receptors. Correlation to the X-ray Structure of “THIQ”

Journal of medicinal chemistry, 2004-08, Vol.47 (18), p.4613-4626

2004

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Anorexigenic cocaine- and amphetamine-regulated transcript peptide intensifies fear reactions in rats

Brain research, 2000-02, Vol.857 (1), p.283-285

2000

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The MC3 receptor binding affinity of melanocortins correlates with the nitric oxide production inhibition in mice brain inflammation model

Peptides (New York, N.Y. : 1980), 2006-06, Vol.27 (6), p.1443-1450

2006

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Differential influence of a selective melanocortin MC4 receptor antagonist (HS014) on melanocortin-induced behavioral effects in rats

European journal of pharmacology, 1998-12, Vol.362 (2-3), p.95-101

1998

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New highly specific agonistic peptides for human melanocortin MC1 receptor

Peptides (New York, N.Y. : 1980), 2000-02, Vol.21 (2), p.239-243

2000

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Reductive amination products containing naphthalene and indole moieties bind to melanocortin receptors

Bioorganic & medicinal chemistry letters, 2002-04, Vol.12 (7), p.1035-1038

2002

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N-alkylaminoacids and their derivatives interact with melanocortin receptors

Bioorganic & medicinal chemistry letters, 2002-04, Vol.12 (7), p.1039-1042

2002

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Novel selective melanocortin 4 receptor antagonist induces food intake after peripheral administration

Biochemical and biophysical research communications, 2003-02, Vol.301 (2), p.399-405

2003

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The MC sub(3) receptor binding affinity of melanocortins correlates with the nitric oxide production inhibition in mice brain inflammation model

Peptides (New York, N.Y. : 1980), 2006-06, Vol.27 (6), p.1443-1450

2006

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Targeting melanocortin receptors: an approach to treat weight disorders and sexual dysfunction

A look inside HIV resistance through retroviral protease interaction maps

Selective Antagonist for the Melanocortin 4 Receptor (HS014) Increases Food Intake in Free-Feeding Rats

Proteochemometric Mapping of the Interaction of Organic Compounds with Melanocortin Receptor Subtypes

Design and synthesis of a library of tertiary amides: Evaluation as mimetics of the melanocortins’ active core

Oligomerization of indole derivatives with incorporation of thiols

Phage Display Selection on Whole Cells Yields a Peptide Specific for Melanocortin Receptor 1

Long term orexigenic effect of a novel melanocortin 4 receptor selective antagonist

2-(p-Hydroxybenzyl)indoles - Side Products Formed Upon Cleavage of Indole Derivatives from Carboxylated Wang Polymer - an NMR Study

Libiguins A and B: novel phragmalin limonoids isolated from Neobeguea mahafalensis causing profound enhancement of sexual activity

Probing the substrate specificity of the dengue virus type 2 NS3 serine protease by using internally quenched fluorescent peptides

Discovery of novel melanocortin 4 receptor selective MSH analogues

The MC4 receptor mediates α-MSH induced release of nucleus accumbens dopamine

QSAR and Proteo-chemometric Analysis of the Interaction of a Series of Organic Compounds with Melanocortin Receptor Subtypes

Kinetic evidence for tandemly arranged ligand binding sites in melanocortin 4 receptor complexes

New Substituted Piperazines as Ligands for Melanocortin Receptors. Correlation to the X-ray Structure of “THIQ”

Anorexigenic cocaine- and amphetamine-regulated transcript peptide intensifies fear reactions in rats

The MC3 receptor binding affinity of melanocortins correlates with the nitric oxide production inhibition in mice brain inflammation model

Differential influence of a selective melanocortin MC4 receptor antagonist (HS014) on melanocortin-induced behavioral effects in rats

New highly specific agonistic peptides for human melanocortin MC1 receptor

Reductive amination products containing naphthalene and indole moieties bind to melanocortin receptors

N-alkylaminoacids and their derivatives interact with melanocortin receptors

Novel selective melanocortin 4 receptor antagonist induces food intake after peripheral administration

The MC sub(3) receptor binding affinity of melanocortins correlates with the nitric oxide production inhibition in mice brain inflammation model

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